Habilitation à diriger des recherches

Autor: PASDELOUP, David

Publikováno v: Virologie. Université de Tours, 2019

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ecf8f0916e2964b83e21501e047299c8
https://hal.inrae.fr/tel-02939275/document

Oncogenic marek’s disease herpesvirus encodes an isoform of the conserved regulatory immediate early protein ICP27 generated by alternative promoter usage

Autor: Swantje Strassheim, Benoît Muylkens, Denis Rasschaert, Isabelle Gennart, S. Laurent, Marjolaine André

Publikováno v: Journal of General Virology
Journal of General Virology, Microbiology Society, 2016, 97, pp.2399-2410. ⟨10.1099/jgv.0.000547⟩

Herpesvirus gene expression is temporally regulated, with immediate early (IE), early (E) and late (L) genes. ICP27, which is involved in post-transcriptional regulation, is the only IE gene product conserved in all herpesviruses. We show here that t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0ed8ac5cd3dc0e97c904188120feca
https://doi.org/10.1099/jgv.0.000547

Atrophy of primary lymphoid organs induced by Marek’s Disease Virus during early infection is associated with increased apoptosis, inhibition of cell proliferation and a severe B- lymphopenia

Autor: Caroline Denesvre, Camille Berthault, Thibaut Larcher, Sonja Härtle, Jean-François Vautherot, Laëtitia Trapp-Fragnet

Publikováno v: 11. Symposium of the French Domestic Animal Immunology Network (IAD 2018)
11. Symposium of the French Domestic Animal Immunology Network (IAD 2018), Mar 2018, Tours, France. 56 p
Veterinary Research
Veterinary Research, BioMed Central, 2018, 49 (1), pp.1-18. ⟨10.1186/s13567-018-0526-x⟩
Veterinary Research 1 (49), 1-18. (2018)
Veterinary Research, Vol 49, Iss 1, Pp 1-18 (2018)

Marek’s disease is a multi-faceted highly contagious disease affecting chickens caused by the Marek’s disease alphaherpesvirus (MDV). MDV early infection induces a transient immunosuppression, which is associated with thymus and bursa of Fabriciu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06bf12c8f4fd12e2db83a87e5fd2984
https://hal.inrae.fr/hal-02733563

Induction of DNA Damages upon Marek's Disease Virus Infection: Implication in Viral Replication and Pathogenesis

Autor: Sylvie Rémy, Caroline Denesvre, Luca D. Bertzbach, Yves Le Vern, Tereza Vychodil, Laëtitia Trapp-Fragnet, Djihad Bencherit, Benedikt B. Kaufer

Publikováno v: Journal of Virology 24 (91), 1-36. (2017)
Journal of Virology
Journal of Virology, American Society for Microbiology, 2017, 91 (24), 16 p. ⟨10.1128/JVI.01658-17⟩

Marek's disease virus (MDV) is a highly contagious alphaherpesvirus that infects chickens and causes a deadly neoplastic disease. We previously demonstrated that MDV infection arrests cells in S phase and that the tegument protein VP22 plays a major

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4097869aa2945713691ccf69f8581062
https://pubmed.ncbi.nlm.nih.gov/28978699

Keratinocytes derived from chicken embryonic stem cells support Marek's disease virus infection: a highly differentiated cell model to study viral replication and morphogenesis

Autor: Caroline Denesvre, Jean-François Vautherot, Laetitia Trapp-Fragnet, Katia Courvoisier, Mathilde Couteaudier

Publikováno v: Virology Journal
Virology Journal, BioMed Central, 2016, 13 (1), pp.1-7. ⟨10.1186/s12985-015-0458-2⟩
Virology journal 1 (13), 1-7. (2016)

Background Marek’s disease is a virus disease with worldwide distribution that causes major losses to poultry production. Vaccines against Marek’s disease virus, an oncogenic alphaherpesvirus, reduce tumour formation but have no effect on virus s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::561346e73109a066cad10bfb044b09ae
https://hal.archives-ouvertes.fr/hal-01275145