Zobrazeno 1 - 10
of 1 382
pro vyhledávání: '"major histocompatibility complex (MHC)"'
Autor:
Yasunari Matsuzaka, Ryu Yashiro
Publikováno v:
BioMedInformatics, Vol 4, Iss 3, Pp 1835-1864 (2024)
Human Leukocyte Antigen (HLA) is like a device that monitors the internal environment of the body. T lymphocytes immediately recognize the HLA molecules that are expressed on the surface of the cells of the different individual, attacking it defeats
Externí odkaz:
https://doaj.org/article/0c7ad812977745b7b1735227639ecfee
Autor:
Raya Saleh, Erik Sundberg, Mia Olsson, Katarina Tengvall, Lars Alfredsson, Ingrid Kockum, Leonid Padyukov, Helena Erlandsson Harris
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Juvenile Idiopathic Arthritis (JIA) is a complex autoimmune disease and the most common chronic rheumatological disease affecting children under the age of 16. The etiology of JIA remains poorly understood, but evidence suggests a
Externí odkaz:
https://doaj.org/article/d8bc63d7b96a48848186f553c014605d
Publikováno v:
Veterinary Medicine and Science, Vol 10, Iss 6, Pp n/a-n/a (2024)
ABSTRACT Background Stress associated with changes in host immunity occurs in response to altered environmental conditions, endogenous imbalances, infectious agents and harmful stimuli. The importance of genetic diversity in chickens has increased du
Externí odkaz:
https://doaj.org/article/97c1b22e3e304353961b94787c6b92be
Autor:
Minjun Kim, Thisarani Kalhari Ediriweera, Eunjin Cho, Yoonji Chung, Prabuddha Manjula, Myunghwan Yu, John Kariuki Macharia, Seonju Nam, Jun Heon Lee
Publikováno v:
Animal Bioscience, Vol 37, Iss 6, Pp 993-1000 (2024)
Objective This study was conducted to investigate the differential expression of the major histocompatibility complex (MHC) gene region in Eimeria-infected broiler. Methods We profiled gene expression of Eimeria-infected and uninfected ceca of broile
Externí odkaz:
https://doaj.org/article/bbe56b49c811438791ef730b6655796f
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Variation within the non-coding genome may influence the regulation and expression of important genes involved in immune control such as the human leukocyte antigen (HLA) system. Class I and Class II HLA molecules are essential for peptide presentati
Externí odkaz:
https://doaj.org/article/1cc1ba99ff63445aa90080fb2240b00f
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The Human leukocyte antigen (HLA) molecules are central to immune response and have associations with the phenotypes of various diseases and induced drug toxicity. Further, the role of HLA molecules in presenting antigens significantly affec
Externí odkaz:
https://doaj.org/article/0041fad8ddf94651a1d3d8d9cf895583
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionParkinson’s disease (PD) is a neurodegenerative and polygenic disorder characterised by the progressive loss of neural dopamine and onset of movement disorders. We previously described eight SINE-VNTR-Alu (SVA) retrotransposon-insertion
Externí odkaz:
https://doaj.org/article/7257bcbcd1bb4b03a073b3c479c1e84b
Autor:
Yuta Nagano, Benjamin Chain
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
T cell receptors (TR) underpin the diversity and specificity of T cell activity. As such, TR repertoire data is valuable both as an adaptive immune biomarker, and as a way to identify candidate therapeutic TR. Analysis of TR repertoires relies heavil
Externí odkaz:
https://doaj.org/article/3783e02a9d7a4efb824dccb1f2504b1b
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Head and neck tumors (HNCs) are a common tumor in otorhinolaryngology head and neck surgery, accounting for 5% of all malignant tumors in the body and are the sixth most common malignant tumor worldwide. In the body, immune cells can recogni
Externí odkaz:
https://doaj.org/article/77c0ab0cf5cd4079a00c8083fdeee002
Publikováno v:
Poultry Science, Vol 102, Iss 9, Pp 102881- (2023)
ABSTRACT: The major histocompatibility complex (MHC) is a highly polymorphic cluster of genes which contribute to immune response. Located on chromosome 16, the chicken MHC has great influence over disease resistance and susceptibility. Through the u
Externí odkaz:
https://doaj.org/article/83d381ad775c4cdbacbbfd3285f5f63e