Preclinical development and pharmacokinetic assessment in macaques of a multipurpose long-acting injectable suspension containing medroxyprogesterone acetate for contraception and rilpivirine for HIV prevention

Autor: Clément M. Haeck, Peter Boyd, Nastasia Dimant, Aurélie Barrail-Tran, Hélène Gouget, Roger Le Grand, Delphine Desjardins, R. Karl Malcolm

Publikováno v: Haeck, C M, Boyd, P, Dimant, N, Barrail-Tran, A, Gouget, H, Le Grand, R, Desjardins, D & Malcolm, R K 2023, ' Preclinical development and pharmacokinetic assessment in macaques of a multipurpose long-acting injectable suspension containing medroxyprogesterone acetate for contraception and rilpivirine for HIV prevention ', Journal of Drug Delivery Science and Technology, vol. 85, 104590 . https://doi.org/10.1016/j.jddst.2023.104590

Depot injections comprising aqueous drug suspensions are widely marketed for long-acting administration of contraceptive progestins and antipsychotics. In recent years, there has been considerable interest in developing similar long-acting injectable

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d7fe4b20d90db8626538b53308ade3
https://doi.org/10.1016/j.jddst.2023.104590