Zobrazeno 1 - 10
of 405
pro vyhledávání: '"mTOR—mammalian target of rapamycin"'
Autor:
Luca Lo Nigro
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/2ec61df6490f40a8a1295cbbb617c3c2
Autor:
Ji-Hee Yeo, Dae-Hyun Roh
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Neuropathic pain caused by trigeminal nerve injury is a typical refractory orofacial chronic pain accompanied by the development of hyperalgesia and allodynia. We previously demonstrated that the mammalian target of rapamycin (mTOR) inhibitor rapamyc
Externí odkaz:
https://doaj.org/article/afa18130a0a243e1b8be52554a7e6cc5
Autor:
Elise F. Nassif, Cissimol P. Joseph, Rossana Lazcano, Jocelyn T. Joseph, Prapassorn Thirasastr, Alexander J. Lazar, Neeta Somaiah
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
TSC-mutated sarcomas are rare molecular and histologic types of sarcoma. Due to the presence of their specific oncogenic driver mutation, these sarcomas are particularly sensitive to mTOR inhibitors. Recently, nab-sirolimus, an albumin-bound mTOR inh
Externí odkaz:
https://doaj.org/article/a1c63b7a8b594de2b203ca711e8f1b8a
Autor:
Rahimeh Emamnejad, Mary Dass, Michael Mahlis, Salome Bozkurt, Sining Ye, Maurice Pagnin, Paschalis Theotokis, Nikolaos Grigoriadis, Steven Petratos
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Multiple sclerosis (MS) is a heterogeneous autoimmune disease whereby the pathological sequelae evolve from oligodendrocytes (OLs) within the central nervous system and are targeted by the immune system, which causes widespread white matter pathology
Externí odkaz:
https://doaj.org/article/16603ae7026e485798941b8717bb479e
Akademický článek
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Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/58af2c433475464e9c04c38d41f6b3be
Publikováno v:
Frontiers in Aging, Vol 2 (2021)
Aging and obesity are common risk factors for numerous chronic pathologies, and the compounding effects of old age and increased adiposity pose a serious threat to public health. Starting from the assumption that aging and obesity may have shared und
Externí odkaz:
https://doaj.org/article/341aca0af58541e7843009afda8c5ddb
Autor:
Rajas P. Kale, Thanh Thanh L. Nguyen, J. Blair Price, Nathanael J. Yates, Ken Walder, Michael Berk, Roy V. Sillitoe, Abbas Z. Kouzani, Susannah J. Tye
Publikováno v:
Frontiers in Human Neuroscience, Vol 15 (2021)
The antidepressant actions of deep brain stimulation (DBS) are associated with progressive neuroadaptations within the mood network, modulated in part, by neurotrophic mechanisms. We investigated the antidepressant-like effects of chronic nucleus acc
Externí odkaz:
https://doaj.org/article/e38ba7c1b5d648cc87329b03f35a04fd
Autor:
Donald L. Mykles
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
A pair of Y-organs (YOs) are the molting glands of decapod crustaceans. They synthesize and secrete steroid molting hormones (ecdysteroids) and their activity is controlled by external and internal signals. The YO transitions through four physiologic
Externí odkaz:
https://doaj.org/article/b19c0e7c9efc45e384dd6966ff31c735