Zobrazeno 1 - 10
of 15
pro vyhledávání: '"mTOR, the mammalian target of rapamycin"'
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The recognition of ω-3 polyunsaturated acids (PUFAs) as essential fatty acids to normal growth and health was realized more than 80 years ago. However, the awareness of the long-term nutritional intake of ω-3 PUFAs in lowering the risk of a variety
Externí odkaz:
https://doaj.org/article/ee25b96ae4674975b864465e8fe03891
Autor:
Lu Feng, Kai Zhang, Bo Liu, Tingting Jiang, Liang Ouyang, Guan Wang, Jiamei Li, Shiou Zhu, Junping Pei
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3015-3034 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Parkinson's disease (PD), known as one of the most universal neurodegenerative diseases, is a serious threat to the health of the elderly. The current treatment has been demonstrated to relieve symptoms, and the discovery of new small-molecule compou
Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 6, Pp 771-778 (2020)
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal : SPJ
The quality of life, in itself, in cancer patients or in osteoporotic individuals, without even considering the side effects of the medication in the first place, has a considerable negative impact on the clinical outcome. The Medication Related Oste
Publikováno v:
Translational Research
As the world navigates the coronavirus disease 2019 (COVID-19) pandemic, there is a growing need to assess its impact in patients with autoimmune rheumatic diseases, such as systemic lupus erythematosus (SLE). Patients with SLE are a unique populatio
Autor:
Roberta L. Beauchamp, Vijaya Ramesh, Justin T. Jordan, Serkan Erdin, Scott R. Plotkin, James F. Gusella, Luke Witt
Publikováno v:
The Journal of Biological Chemistry
Meningiomas (MNs), arising from the arachnoid/meningeal layer, are nonresponsive to chemotherapies, with ∼50% showing loss of the Neurofibromatosis 2 (NF2) tumor suppressor gene. Previously, we established NF2 loss activates mechanistic target of r
Autor:
Gregory R. Steinberg, Bassem Mekhaeil, Tobias Berg, Theodoros Tsakiridis, Lindsay A. Broadfield, Olga-Demetra Biziotis, Katarina Marcinko, Alexander E. Anagnostopoulos, Paola Muti, Amr Ali, Elham Ahmadi, Panayiotis G. Zacharidis, Aruz Mesci, Evangelia E. Tsakiridis, Kanwaldeep Singh
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 11, Pp 101209-(2021)
Translational Oncology, Vol 14, Iss 11, Pp 101209-(2021)
Highlights • Combined metformin + salicylate treatment has improved anti-tumor efficacy in prostate cancer. • At clinically achievable doses, it induces increased metabolic stress and sensitizes tumors to radiation. • Metformin + salicylate blo
Autor:
Jyrki J. Eloranta, Anne Terhalle, Gerhard Rogler, Pedro A. Ruiz, Arnold von Eckardstein, Jesus Cosin-Roger, Ragam Gerster, Urs Ziegler, Martin Hausmann, Gerd A. Kullak-Ublick
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 2, Pp 171-187.e1 (2015)
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 2, Pp 171-187.e1 (2015)
Background & Aims: Plasma levels of high-density lipoprotein (HDL) cholesterol are frequently found decreased in patients with inflammatory bowel disease (IBD). Therefore, and because HDL exerts anti-inflammatory activities, we investigated whether H
Autor:
Calum C. Bain, Foo Y. Liew, Ananda S. Mirchandani, Anne-Gaelle Besnard, Neil C. Thomson, Robert J. Salmond
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background: The IL-1 family cytokine IL-33 is involved in the induction of airway inflammation in allergic patients and after viral infection. Several cell types, including CD4 1 TH2 cells and the recently described type 2 innate lymphoid cells (ILCs
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Zhang K; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China., Zhu S; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China., Li J; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China., Jiang T; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China., Feng L; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China., Pei J; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China., Wang G; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China.; Innovation Center of Nursing Research, Nursing Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu 610041, China., Ouyang L; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China., Liu B; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2021 Oct; Vol. 11 (10), pp. 3015-3034. Date of Electronic Publication: 2021 Feb 26.