Zobrazeno 1 - 10
of 2 476
pro vyhledávání: '"mGluR5"'
Autor:
Jinlong Wang, Bo Cao
Publikováno v:
Case Reports in Neurology, Vol 16, Iss 1, Pp 249-255 (2024)
Introduction: Spinal teratomas are rare, accounting for nearly 0.2–0.5% of all spinal tumors and 2% of all teratomas. Teratomas at the conus medullaris location do not inherently lead to epilepsy. However, potential epileptic seizures are caused wh
Externí odkaz:
https://doaj.org/article/018d75254cfb48a2a3c29e3022d87800
Publikováno v:
Chemical Physics Impact, Vol 9, Iss , Pp 100691- (2024)
Abstracts: Metabotropic glutamate receptors (mGluRs) are G-protein-coupled receptors activated by glutamate. A series of 90 novel compounds have been assessed as mGluR5 receptor antagonists. These compounds, selected post-ADMET filtering according to
Externí odkaz:
https://doaj.org/article/4628c3dfe06541aeb3166e4d921db883
Autor:
Rosa Fernández, Karla Ramírez, Roberto Lorente-Bermúdez, Esther Gómez-Gil, Mireia Mora, Antonio Guillamon, Eduardo Pásaro
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionGender incongruence (GI) is characterized by a marked incongruence between an individual’s experienced/expressed gender and the assigned sex at birth. It includes strong displeasure about his or her sexual anatomy and secondary sex char
Externí odkaz:
https://doaj.org/article/846245694a8844f39a9d1fd164972431
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-10 (2024)
Abstract One of the main hallmarks of Parkinson’s disease (PD) is abnormal alpha-synuclein (α-syn) aggregation which forms the main component of intracellular Lewy body inclusions. This short report used preformed α-syn fibrils, as well as an A53
Externí odkaz:
https://doaj.org/article/e5a200be4ccc46d083476d4ce66f614b
Publikováno v:
Heliyon, Vol 10, Iss 8, Pp e29483- (2024)
Methylene blue (MB) was found to exert neuroprotective effect on different brain diseases, such as ischemic stroke. This study assessed the MB effects on ischemia induced brain edema and its role in the inhibition of aquaporin 4 (AQP4) and metabotrop
Externí odkaz:
https://doaj.org/article/c949acc14a7a4f8481ff2d3a0ee5be68
Publikováno v:
Pharmacological Research, Vol 200, Iss , Pp 107081- (2024)
Ketamine, a non-competitive N-methyl-D-aspartate receptor (NMDAR) antagonist, has received much attention for its rapid antidepressant effects. A single administration of ketamine elicits rapid and sustained antidepressant effects in both humans and
Externí odkaz:
https://doaj.org/article/7ca44c8dcbf54a4aa032e2d27d6f68a2
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ObjectiveMetabotropic glutamate receptor 5 (mGluR5) encephalitis is such a rare type of autoimmune encephalitis that its diagnosis remains a challenge.Case reportA 19-year-old female patient initially presented with anxiety and orthostatic leg tremor
Externí odkaz:
https://doaj.org/article/e0770a966ad84ad8acd1c543c906d57e
Autor:
Izabella B. Q. de Lima, Pablo L. Cardozo, Julia S. Fahel, Juliana P. S. Lacerda, Aline S. Miranda, Antônio L. Teixeira, Fabiola M. Ribeiro
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
TNF-α is essential for induction and maintenance of inflammatory responses and its dysregulation is associated with susceptibility to various pathogens that infect the central nervous system. Activation of both microglia and astrocytes leads to TNF-
Externí odkaz:
https://doaj.org/article/1a8466f29a134b11975f43ec5774b486
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Akademický článek
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