Zobrazeno 1 - 10
of 66
pro vyhledávání: '"mAbs, monoclonal antibodies"'
Autor:
Ajay Badhan, Kristin E. Low, Darryl R. Jones, Xiaohui Xing, Mohammad Raza Marami Milani, Rodrigo Ortega Polo, Leeann Klassen, Sivasankari Venketachalam, Michael G. Hahn, D. Wade Abbott, Tim A. McAllister
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 20, Iss, Pp 148-164 (2022)
Computational and Structural Biotechnology Journal, Vol 20, Iss, Pp 148-164 (2022)
Graphical abstract
There is a knowledge gap regarding the factors that impede the ruminal digestion of plant cell walls or if rumen microbiota possess the functional activities to overcome these constraints. Innovative experimental methods were
There is a knowledge gap regarding the factors that impede the ruminal digestion of plant cell walls or if rumen microbiota possess the functional activities to overcome these constraints. Innovative experimental methods were
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 1, Pp 55-70 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Cancer stem cells (CSCs) are a subpopulation of cancer cells with functions similar to those of normal stem cells. Although few in number, they are capable of self-renewal, unlimited proliferation, and multi-directional differentiation potential. In
Autor:
Branislav Kovacech, Lubica Fialova, Peter Filipcik, Rostislav Skrabana, Monika Zilkova, Natalia Paulenka-Ivanovova, Andrej Kovac, Denisa Palova, Gabriela Paulikova Rolkova, Katarina Tomkova, Natalia Turic Csokova, Karina Markova, Michaela Skrabanova, Kristina Sinska, Neha Basheer, Petra Majerova, Jozef Hanes, Vojtech Parrak, Michal Prcina, Ondrej Cehlar, Martin Cente, Juraj Piestansky, Michal Fresser, Michal Novak, Monika Slavikova, Kristina Borsova, Viktoria Cabanova, Bronislava Brejova, Tomas Vinař, Jozef Nosek, Boris Klempa, Ludek Eyer, Vaclav Hönig, Martin Palus, Daniel Ruzek, Tereza Vyhlidalova, Petra Strakova, Blanka Mrazkova, Dagmar Zudova, Gizela Koubkova, Vendula Novosadova, Jan Prochazka, Radislav Sedlacek, Norbert Zilka, Eva Kontsekova
Publikováno v:
EBioMedicine, Vol 76, Iss, Pp 103818-(2022)
EBioMedicine
eBioMedicine
EBioMedicine
eBioMedicine
Summary: Background: The emergence of new SARS-CoV-2 variants of concern B.1.1.7 (Alpha), B.1.351 (Beta), P.1 (Gamma) and B.1.617.2 (Delta) that harbor mutations in the viral S protein raised concern about activity of current vaccines and therapeutic
Autor:
Abdallah A. Hassanin, Sayed Haidar Abbas Raza, Javed Ahmed Ujjan, Ayshah Aysh ALrashidi, Basel M. Sitohy, Ameena A. AL-surhanee, Ahmed M. Saad, Tahani Mohamed Al -Hazani, Osama Osman Atallah, Khalid M. Al Syaad, Ahmed Ezzat Ahmed, Ayman A. Swelum, Mohamed T. El-Saadony, Mahmoud Z. Sitohy
Publikováno v:
Saudi Journal of Biological Sciences
The emergence of coronavirus disease 2019 (COVID-19) pandemic in Wuhan city, China at the end of 2019 made it urgent to identify the origin of the causal pathogen and its molecular evolution, to appropriately design an effective vaccine. This study a
Autor:
Cassiano Martin Batista, Leonardo Foti
Publikováno v:
International Immunopharmacology
Graphical abstract SARS-CoV-2 infected alveoli and the different types of the two antibody-based treatments discussed in this review. Can antibodies be used to protect against COVID-19 and neutralize autoantibodies?
Coronavirus disease 2019 (COV
Coronavirus disease 2019 (COV
Autor:
Jiang Wang, Hualiang Jiang, Hong Liu, Chenglin Wu, Zhao Jing, Wang Yiping, Junhua Tong, Xi Cong
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 9, Iss 6, Pp 1216-1230 (2019)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators may attenuate PCSK9-induced low-density lipoprotein receptor (LDLR) degradation in lysosome and promote the clearance of circulating low-density lipoprotein cholesterol (LDL-C). A novel
Autor:
Zewei Jiang, Joshua Kesterson, Rebecca Phaeton, Joshua I. Warrick, Rouzan G. Karabakhtsian, Joseph Albanese, Ekaterina Dadachova
Publikováno v:
Translational Oncology, Vol 12, Iss 10, Pp 1289-1295 (2019)
Translational Oncology
Translational Oncology
Nearly all cases of cervical cancer are initiated by persistent infection with high-risk strains of human papillomavirus (hr-HPV). When hr-HPV integrates into the host genome, the constitutive expression of oncogenic HPV proteins E6 and E7 function t
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 9, Iss 5, Pp 960-972 (2019)
Acta Pharmaceutica Sinica B, Vol 9, Iss 5, Pp 960-972 (2019)
Monoclonal antibodies (mAbs) are widely used in many fields due to their high specificity and ability to recognize a broad range of antigens. IL-17A can induce a rapid inflammatory response both alone and synergistically with other proinflammatory cy
Publikováno v:
Gastroenterology
Risk factors for hepatitis C virus (HCV) infection vary, and there were an estimated 1.75 million new cases worldwide in 2015. The World Health Organization aims for a 90% reduction in new HCV infections by 2030. An HCV vaccine would prevent transmis
Autor:
Elena Ortona, Valentina Giudice, Andrea Cignarella, Marina Ziche, Amelia Filippelli, Silvia De Francia, Vincenzo Brancaleone, Andrea Spini, Luigia Trabace, Anna Ruggieri, Maria Grazia Morgese
Publikováno v:
Pharmacological Research
Pharmacological Research, 2021, 173, pp.105848. ⟨10.1016/j.phrs.2021.105848⟩
Pharmacological Research, 2021, 173, pp.105848. ⟨10.1016/j.phrs.2021.105848⟩
Making gender bias visible allows to fill the gaps in knowledge and understand health records and risks of women and men. The coronavirus disease 2019 (COVID-19) pandemic has shown a clear gender difference in health outcomes. The more severe symptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3220f6ea3907610cc7e81df83b367a62
http://hdl.handle.net/2318/1798821
http://hdl.handle.net/2318/1798821