Zobrazeno 1 - 10
of 2 273
pro vyhledávání: '"mAbs"'
Autor:
Hassan Aboul-Ella, Asmaa Gohar, Aya Ahmed Ali, Lina M. Ismail, Adham Ezz El-Regal Mahmoud, Walid F. Elkhatib, Heba Aboul-Ella
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-44 (2024)
Abstract Monoclonal antibodies (mAbs) are used to prevent, detect, and treat a broad spectrum of non-communicable and communicable diseases. Over the past few years, the market for mAbs has grown exponentially with an expected compound annual growth
Externí odkaz:
https://doaj.org/article/d8db5e7cec4d4870a337c03fbb191bb3
Autor:
Mario Rivera-Izquierdo, Arturo Morales-Portillo, Inmaculada Guerrero-Fernández de Alba, Nicolás Francisco Fernández-Martínez, Joan Antoni Schoenenberger-Arnaiz, José Luis Barranco-Quintana, Carmen Valero-Ubierna
Publikováno v:
Expert Review of Vaccines, Vol 23, Iss 1, Pp 887-910 (2024)
Introduction Monoclonal antibodies (mAbs) and other biological agents are being increasingly approved in the last years with very different indications. Their highly heterogeneous immunosuppressive effects, mechanisms of action and pharmacokinetics r
Externí odkaz:
https://doaj.org/article/5cc042de4c474f45a384a3ba586260ed
Autor:
Qi Pan, Xiaomin Xing, Jianhai Yu, Qiang Chen, Haizhan Jiao, Wanqin Zhang, Yingfen Wen, Ming Gao, Wei Zhao, Lei Yu, Hongli Hu
Publikováno v:
hLife, Vol 2, Iss 10, Pp 527-541 (2024)
Antibodies targeting non-structural protein 1 (NS1) confer protection against Zika virus (ZIKV). Although monoclonal antibodies (MAbs) 3G2 and 4B8 are more potent than MAb 4F10 in suppressing ZIKV infection in neonatal mice models, the epitopes are u
Externí odkaz:
https://doaj.org/article/61d25f68b43e4ecbb7e58764238adbda
Autor:
Hélène Banoun
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 9, Pp 10369-10395 (2024)
Respiratory infections with respiratory syncytial virus (RSV) account for an important part of hospital admissions for acute respiratory infections. Nirsevimab has been developed to reduce the hospital burden of RSV infections. Compared with the prod
Externí odkaz:
https://doaj.org/article/95e6886d4c7a4808b761a00eb9cf3ea5
Autor:
Prakit Anukoolwittaya, Akarin Hiransuthikul, Thanakit Pongpitakmetha, Sekh Thanprasertsuk, Wanakorn Rattanawong
Publikováno v:
The Journal of Headache and Pain, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Most real-world data on CGRP mAbs have been published from high-income countries such as the USA, Western countries, Japan, Korea, and Singapore. However, data from low- and middle-income countries in Southeast Asia is lacking. Th
Externí odkaz:
https://doaj.org/article/8e64752ba0164aa29ab5d17aa93586a1
Autor:
Jing Song, Marc Taraban, Y. Bruce Yu, Lynn Lu, Pallavi Guha Biswas, Wei Xu, Hanmi Xi, Akhilesh Bhambhani, Guangli Hu, Yongchao Su
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTHigh-concentration protein formulation is of paramount importance in patient-centric drug product development, but it also presents challenges due to the potential for enhanced aggregation and increased viscosity. The analysis of critical qua
Externí odkaz:
https://doaj.org/article/8d8f3e96eb104bfea17977931edd4cd5
Autor:
Oksana Malanchuk, Antonina Khoruzhenko, Viktoriia Kosach, Anna Bdzhola, Dariy Bidiuk, Charlie Brett, Ivan Gout, Valeriy Filonenko
Publikováno v:
Biology Open, Vol 13, Iss 10 (2024)
Externí odkaz:
https://doaj.org/article/319aa1b9739d4bdf81c85193cb26a8b2
Publikováno v:
The Journal of Headache and Pain, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Migraine is a highly prevalent neurological disease with a substantial societal burden due to lost productivity. From a societal perspective, we assessed the cost-effectiveness of eptinezumab for the preventive treatment of migrai
Externí odkaz:
https://doaj.org/article/fca3cd0fb19d4594a041cd2b7b168b47
Autor:
Vishnu Priya Veeraraghavan, Shikhar Daniel, Arun Kumar Dasari, Kaladhar Reddy Aileni, Chaitra patil, Santosh R. Patil
Publikováno v:
Oral Oncology Reports, Vol 11, Iss , Pp 100592- (2024)
This comprehensive study explored the role of epidermal growth factor receptor (EGFR)-targeted therapies in oral cancer, focusing on emerging strategies, challenges, and future directions. The EGFR signalling pathway plays a critical role in the deve
Externí odkaz:
https://doaj.org/article/5b78da09e6684f49b33fd5d27e0603f0
Autor:
Hongyu Qiu, Xin-Yong Yuan, Kimberly Holloway, Heidi Wood, Teresa Cabral, Chris Grant, Peter McQueen, Garrett Westmacott, Daniel R. Beniac, Lisa Lin, Michael Carpenter, Darwyn Kobasa, Tom Gräfenhan, Ian Wayne Cheney
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35325- (2024)
Rapid antigen test (RAT) is widely used for SARS-CoV-2 infection diagnostics. However, test sensitivity has decreased recently due to the emergence of the Omicron variant and its sublineages. Here we developed a panel of SARS-CoV-2 nucleocapsid prote
Externí odkaz:
https://doaj.org/article/58d0d5e57f6643e6912fcacc854a3573