Zobrazeno 1 - 10
of 493
pro vyhledávání: '"m7G"'
Autor:
Lu Tang, Hua Tian, Qi Min, Huili You, Mengshuang Yin, Liqiong Yang, Yueshui Zhao, Xu Wu, Mingxing Li, Fukuan Du, Yu Chen, Shuai Deng, Xiaobing Li, Meijuan Chen, Li Gu, Yuhong Sun, Zhangang Xiao, Wanping Li, Jing Shen
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-35 (2024)
Abstract As the role of RNA modification in gene expression regulation and human diseases, the “epitranscriptome” has been shown to be an important player in regulating many physiological and pathological processes. Meanwhile, the phenomenon of c
Externí odkaz:
https://doaj.org/article/bf3e86d37ca64ad1ae63b32316260502
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract Plenty of circRNAs have been reported to play an important role in colorectal cancer (CRC), while the reason of abnormal circRNA expression in cancer still keep elusive. Here, we found that m7G RNA modifications were enriched in some circRNA
Externí odkaz:
https://doaj.org/article/63421d25c240434598ccac31d9695305
Autor:
Rong Xu, Ashuai Du, Xinpei Deng, Wei Du, Kaiying Zhang, Jianbo Li, Yingxue Lu, Xiaoli Wei, Qinglong Yang, Hailin Tang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background tRNA-derived small RNAs (tsRNAs) are newly discovered non-coding RNA, which are generated from tRNAs and are reported to participate in several biological processes in diseases, especially cancer; however, the mechanism of tsRNA i
Externí odkaz:
https://doaj.org/article/75d41d7449714cf7a822002e9d2bb575
eIF4E orchestrates mRNA processing, RNA export and translation to modify specific protein production
Publikováno v:
Nucleus, Vol 15, Iss 1 (2024)
The eukaryotic translation initiation factor eIF4E acts as a multifunctional factor that simultaneously influences mRNA processing, export, and translation in many organisms. Its multifactorial effects are derived from its capacity to bind to the met
Externí odkaz:
https://doaj.org/article/cc117cf3379445b7b80b015946b17d39
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
BackgroundOvarian cancer is the most mortality malignancy in gynecology. N7-methylguanosine (m7G) is one of the most prevalent RNA modifications in the development and progression of cancer. The aim of this study is to investigate the effect of m7G-r
Externí odkaz:
https://doaj.org/article/d6af8fc5ad4243db93684afc2f2f22ee
Publikováno v:
World Journal of Surgical Oncology, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Nasopharyngeal carcinoma (NPC) is a type of malignant tumor with high morbidity. Aberrant levels of N7-methylguanosine (m7G) are closely associated with tumor progression. However, the characteristics of the tumor microenvironment
Externí odkaz:
https://doaj.org/article/6581af7a7d2d458aaceda2c7aa55c861
Autor:
Yi Liu, Yanji Zhan, Jiao Liu, Zhengze Shen, Yudong Hu, Ling Zhong, Yuan Yu, Bin Tang, Jing Guo
Publikováno v:
Translational Oncology, Vol 51, Iss , Pp 102202- (2025)
Background: Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cancer. 7-Methylguanosine (m7G), one of the most prevalent RNA modifications, has been reported to play an important role in ccRCC progression; however, the speci
Externí odkaz:
https://doaj.org/article/1858fd01a5e543fc8dd07de45bc6bda2
Publikováno v:
Genes and Diseases, Vol 12, Iss 1, Pp 101201- (2025)
microRNAs (miRNAs) are short single-stranded non-coding RNAs between 21 and 25 nt in length in eukaryotic organisms, which control post-transcriptional gene expression. Through complementary base pairing, miRNAs generally bind to their target messeng
Externí odkaz:
https://doaj.org/article/09c45fb0ecbb4292b9cae0d58b878522
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
N7-Methylguanosine (m7G) is important RNA modification at internal and the cap structure of five terminal end of message RNA. It is essential for RNA stability of RNA, the efficiency of translation, and various intracellular RNA processing pathways.
Externí odkaz:
https://doaj.org/article/4ce0dca15b6e43ec8d622c5e7204861b
Autor:
Shuting Yu, ZhiYong Sun, Tiantian Ju, Yingqi Liu, Zhongting Mei, Changhao Wang, Zhezhe Qu, Na Li, Fan Wu, KuiWu Liu, Meixi Lu, Min Huang, Xiaochen Pang, Yingqiong Jia, Ying Li, Yaozhi Zhang, Shunkang Dou, Jianhao Jiang, Xianhui Dong, Chuanhao Huang, Wanhong Li, Yi zhang, Ye Yuan, Baofeng Yang, Weijie Du
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract Cardiac hypertrophy is a key factor driving heart failure (HF), yet its pathogenesis remains incompletely elucidated. Mettl1‐catalyzed RNA N7‐methylguanosine (m7G) modification has been implicated in ischemic cardiac injury and fibrosis.
Externí odkaz:
https://doaj.org/article/756c7df6f0c9451ca897cdaf35020c1a