Zobrazeno 1 - 10
of 67
pro vyhledávání: '"m6A (N6-methyladenosine)"'
Autor:
Zi-Hao Feng, Yan-Ping Liang, Jun-Jie Cen, Hao-Hua Yao, Hai-Shan Lin, Jia-Ying Li, Hui Liang, Zhu Wang, Qiong Deng, Jia-Zheng Cao, Yong Huang, Jin-Huan Wei, Jun-Hang Luo, Wei Chen, Zhen-Hua Chen
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background N6-methyladenosine (m6A) related long noncoding RNAs (lncRNAs) may have prognostic value in bladder cancer for their key role in tumorigenesis and innate immunity. Methods Bladder cancer transcriptome data and the corresponding cl
Externí odkaz:
https://doaj.org/article/c174050369a44a65a5b1c412ae34f42a
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Uveal melanoma (UM) is the most frequent intraocular malignant tumor in adults. N6-Methyladenosine (m6A) methylation is recognized as the most critical epigenetic change and is implicated in the development of many malignancies. However, its prognost
Externí odkaz:
https://doaj.org/article/c6b794cd33ca4bd08cb3c2ad8e81a6d3
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The m6A methylation is reported to function in multiple physiological and pathological processes. However, the functional relevance of m6A modification to post-spinal cord injured (SCI) damage is not yet clear. In the present study, methylated RNA im
Externí odkaz:
https://doaj.org/article/507c7a8c553640df9974bc6c108a991f
Autor:
Yang Chen, Min Shen, Chen Ji, Yanqian Huang, Yun Shi, Li Ji, Yao Qin, Yong Gu, Qi Fu, Heng Chen, Kuanfeng Xu, Tao Yang
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectivesN6-methyladenosine (m6A) is essential in the regulation of the immune system, but the role that its single nucleotide polymorphisms (SNPs) play in the pathogenesis of type 1 diabetes (T1D) remains unknown. This study demonstrated the associ
Externí odkaz:
https://doaj.org/article/d6f969dbd1ae4cd39d61849325395179
Autor:
Jiangtao Yu, Haihua Chen, Haoli Ma, Zhongxiang Zhang, Xiaolu Zhu, Pengcheng Wang, Ruining Liu, Xiaoqing Jin, Yan Zhao
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Recent studies showed that RNA N6-methyladenosine (m6A) plays an important role in neurological diseases. We used methylated RNA immunoprecipitation sequencing (MeRIP-Seq) technology to generate the m6A modification map after traumatic spinal cord in
Externí odkaz:
https://doaj.org/article/0433ac8b1773449b85afa0bb37999eb6
Autor:
Jieqing Chen, Xinhui Liao, Jianli Cheng, Ganglin Su, Fen Yuan, Zhongfu Zhang, Jianting Wu, Hongbing Mei, Wanlong Tan
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Long-chain non-coding RNA (LncRNA) has been found to play an important role in the regulation of the occurrence and progression of renal cell carcinoma (RCC). In this study, we demonstrated that LncRNA NEAT1 expression and m6A methylation level was d
Externí odkaz:
https://doaj.org/article/b84d2003232d4da5a9d041e71374a887
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
As the most prevalent internal modification in mRNA, N6-methyladenosine (m6A) plays broad biological functions via fine-tuning gene expression at the post-transcription level. Such modifications are deposited by methyltransferases (i.e., m6A Writers)
Externí odkaz:
https://doaj.org/article/41b5660654624e00b406d128d22b66b2
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundN6-methyladenosine is the most abundant RNA modification, which plays a prominent role in various biology processes, including tumorigenesis and immune regulation. Multiple myeloma (MM) is the second most frequent hematological malignancy.M
Externí odkaz:
https://doaj.org/article/3c7b5ba13ea542ff81c62e266b4a5283
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
N6-Methyladenosine (m6A) is the most widespread internal RNA modification in several species. In spite of latest advances in researching the biological roles of m6A, its function in the development and progression of bladder cancer remains unclear. I
Externí odkaz:
https://doaj.org/article/b527f069bfac43d29b6180bdc7f219be
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Backgroundm6A-related lncRNAs emerged as potential targets for tumor diagnosis and treatment. This study aimed to identify m6A-regulated lncRNAs in lung squamous cell carcinoma (LUSC) patients.Materials and MethodsRNA sequencing and the clinical data
Externí odkaz:
https://doaj.org/article/73093a1085f64b2499b656683408f2c3