Zobrazeno 1 - 10
of 31 537
pro vyhledávání: '"lysosome"'
Autor:
Veronica Ferrari, Barbara Tedesco, Marta Cozzi, Marta Chierichetti, Elena Casarotto, Paola Pramaggiore, Laura Cornaggia, Ali Mohamed, Guglielmo Patelli, Margherita Piccolella, Riccardo Cristofani, Valeria Crippa, Mariarita Galbiati, Angelo Poletti, Paola Rusmini
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-25 (2024)
Abstract Lysosomes are acidic organelles involved in crucial intracellular functions, including the degradation of organelles and protein, membrane repair, phagocytosis, endocytosis, and nutrient sensing. Given these key roles of lysosomes, maintaini
Externí odkaz:
https://doaj.org/article/77973fc44b674b11964c2d10aa083849
Publikováno v:
Exploration of Digestive Diseases, Vol 3, Iss 6, Pp 428-442 (2024)
Metabolic-associated steatotic liver disease (MASLD) and its pathological version, metabolic dysfunction-associated steatohepatitis (MASH), are becoming the main leading causes of chronic liver disease almost worldwide and are the fastest growing aet
Externí odkaz:
https://doaj.org/article/ed57e7a34706452fbe6e0de6a70c0c8e
Publikováno v:
Taiwanese Journal of Obstetrics & Gynecology, Vol 63, Iss 5, Pp 771-776 (2024)
Objective: To present the ultrasound imaging and genetic diagnosis of a fetus with prenatal lethal form of Gaucher disease. Case report: A 37-year-old primiparous woman was pregnant at her 23 weeks of gestation and the prenatal fetal ultrasound revea
Externí odkaz:
https://doaj.org/article/843b99fd417a415daf64d3afa2e76e0f
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-14 (2024)
Abstract Acute pancreatitis (AP) is a multifaceted inflammatory disorder stemming from the aberrant activation of trypsin within the pancreas. Despite the contribution of various factors to the pathogenesis of AP, such as trypsin activation, dysregul
Externí odkaz:
https://doaj.org/article/1588f04d788348b0bfca6f91e032680a
Autor:
Ranran Zhang, Xiaoyan Huang, Chunling Zhou, Qian Zhang, Dongsheng Jia, Xiaoliang Xie, Ju Zhang
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Dauricine (DAU), a benzyl tetrahydroisoquinoline alkaloid isolated from the root of Menispermum dauricum DC, exhibits promising anti-Alzheimer’s disease (AD) effects, but its underlying mechanisms remain inadequately investigate
Externí odkaz:
https://doaj.org/article/f71749cdbe3644e28b73c103cba9f1ea
Autor:
Mariko Kawamura, Daisuke Katagiri, Yuuka Yamamoto, Keiki Shimada, Satomi Higashi, Masako Otani, Noriko Uesugi, Hideki Takano, Yukiko Shimizu, Tadashi Okamura
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-7 (2024)
Abstract Background Cystinosis is a lysosomal storage disorder characterized by an autosomal recessive phenotype. Intermediate cystinosis, which progresses slowly and causes renal failure, accounts for approximately 5% of all cystinosis cases. Patien
Externí odkaz:
https://doaj.org/article/987c8d760b5f4adc81238a854f22795c
Autor:
Jiangping Fu, Yaohua Chen, Jie Li, Ming Tan, Rui Lin, Jiang Wang, Guirong Wu, Yao Rao, Fudao Wu, Youshu Gao, Maoshu Bai, Pingfei Wang, Fang Wu
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Background Non-small cell lung cancer (NSCLC) is the most common type of tumor globally and the leading cause of cancer-related deaths. Although treatment strategies such as immune checkpoint inhibitors and chemotherapy have advanced, the he
Externí odkaz:
https://doaj.org/article/3f537f9994444f60849ba636daa8bccb
Autor:
Arun Kumar, Manti Kumar Saha, Vipin Kumar, Anupam Bhattacharya, Sagar Barge, Ashis K. Mukherjee, Mohan C. Kalita, Mojibur R. Khan
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-26 (2024)
Abstract Background Proteostasis is a critical aging hallmark responsible for removing damaged or misfolded proteins and their aggregates by improving proteasomal degradation through the autophagy-lysosome pathway (ALP) and the ubiquitin–proteasome
Externí odkaz:
https://doaj.org/article/aa0932f2118e495c882362803d5f1708
Autor:
Li-Ping Zhao, Hao-Jie Wang, Die Hu, Jun-Hu Hu, Zheng-Rong Guan, Li-Hua Yu, Ya-Ping Jiang, Xiao-Qi Tang, Zhao-Huang Zhou, Tian Xie, Jian-Shu Lou
Publikováno v:
Journal of Advanced Research, Vol 62, Iss , Pp 257-272 (2024)
Introduction: β-Elemene (β-ELE), derived from Curcuma wenyujin, has anticancer effect on non-small cell lung cancer (NSCLC). However, the potential target and detail mechanism were still not clear. TFEB is the master regulator of lysosome biogenesi
Externí odkaz:
https://doaj.org/article/6f41ae41c6de4938ab8e6923be52beb5
Autor:
Mark F. Wiser
Publikováno v:
Parasitologia, Vol 4, Iss 3, Pp 222-237 (2024)
Endocytosis is a quintessential feature of eukaryotes, and the emergence of endocytosis played a major role in the origin and evolution of eukaryotes. During the early evolution of eukaryotes, phagocytosis and the digestion of prey (i.e., bacteria) c
Externí odkaz:
https://doaj.org/article/ca0b9061ed1141e8a6e372dec84c0927