Chloroquine and Hydroxychloroquine Myopathy: Clinical Spectrum and Treatment Outcomes

Autor: Elie Naddaf, Pritikanta Paul, Omar F. AbouEzzeddine

Publikováno v: Frontiers in Neurology, Vol 11 (2021)

Chloroquine (CQ) and hydroxychloroquine (HCQ) have been associated with muscle toxicity, mostly described as a proximal myopathy with evidence of lysosomal dysfunction on muscle biopsy. In this retrospective study, we aimed to define the clinical phe

Externí odkaz: https://doaj.org/article/fa7234109be14bcf937f612f9ab0550a

Lysosomal Function Impacts the Skeletal Muscle Extracellular Matrix

Autor: Clarissa A. Henry, Elizabeth C. Coffey, Mary Astumian, Sarah S. Alrowaished, Claire E. Schaffer

Publikováno v: Journal of Developmental Biology; Volume 9; Issue 4; Pages: 52
Journal of Developmental Biology
Journal of Developmental Biology, Vol 9, Iss 52, p 52 (2021)

Muscle development and homeostasis are critical for normal muscle function. A key aspect of muscle physiology during development, growth, and homeostasis is modulation of protein turnover, the balance between synthesis and degradation of muscle prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d39eae920b8d11895f5df7135e0fcab

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.