Lpcat3 deficiency promotes palmitic acid-induced 3T3-L1 mature adipocyte inflammation through enhanced ROS generation

Autor: Hu Jiachun, Deng Yan, Ding Tingbo, Dong Jibin, Liang Yuning, Lou Bin

Publikováno v: Acta Biochimica et Biophysica Sinica, Vol 55, Pp 117-130 (2022)

Phosphatidylcholines (PCs) are major phospholipids in the mammalian cell membrane. Structural remodeling of PCs is associated with many biological processes. Lysophosphatidylcholine acyltransferase 3 (Lpcat3), which catalyzes the incorporation of pol

Externí odkaz: https://doaj.org/article/c021752fb3734f938e76b60e0a9ce0be

Macrophage Lysophosphatidylcholine Acyltransferase 3 Deficiency-Mediated Inflammation Is Not Sufficient to Induce Atherosclerosis in a Mouse Model

Autor: Hui Jiang, Zhiqiang Li, Chongmin Huan, Xian-Cheng Jiang

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 5 (2019)

Mammalian cell membrane phosphatidylcholines (PCs), the major phospholipids, exhibit diversity which is controlled by Lands' cycle or PC remodeling pathway. Lysophosphatidylcholine acyltransferase (LPCAT) is one of the major players in the pathway an

Externí odkaz: https://doaj.org/article/899692d8e27342018b1f79f337775aed

Deletion of lysophosphatidylcholine acyltransferase 3 in myeloid cells worsens hepatic steatosis after a high-fat diet

Autor: Bourgeois, Thibaut, Jalil, Antoine, Thomas, Charles, Magnani, Charlène, Le Guern, Naig, Gautier, Thomas, Pais de Barros, Jean-Paul, Bergas, Victoria, Choubley, Hélène, Mazzeo, Loïc, Menegaut, Louise, Josiane Lebrun, Lorène, Van Dongen, Kévin, Xolin, Marion, Jourdan, Tony, Buch, Chloé, Labbé, Jérome, Saas, Philippe, Lagrost, Laurent, Masson, David, Grober, Jacques

Publikováno v: Journal of Lipid Research
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2021, 62, pp.100013. ⟨10.1194/jlr.RA120000737⟩
Journal of Lipid Research, Vol 62, Iss, Pp 100013-(2021)
Journal of Lipid Research, 2021, 62, pp.100013. ⟨10.1194/jlr.RA120000737⟩

International audience; Recent studies have highlighted an important role for lysophosphatidylcholine acyltransferase 3 (LPCAT3) in controlling the PUFA composition of cell membranes in the liver and intestine. In these organs, LPCAT3 critically supp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::af5f4df163f76772e1ca9f72e454498c
https://hal-agrosup-dijon.archives-ouvertes.fr/hal-03134828

Deletion of lysophosphatidylcholine acyltransferase 3 in myeloid cells worsens hepatic steatosis after a high-fat diet.

Autor: Bourgeois T; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France., Jalil A; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France., Thomas C; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France., Magnani C; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France., Le Guern N; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France., Gautier T; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France., Pais de Barros JP; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France; Lipidomic analytic plate-forme, Univ. Bourgogne Franche-Comté, Batiment B3, Bvd Maréchal de Lattre de Tassigny, Dijon, France., Bergas V; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France; Lipidomic analytic plate-forme, Univ. Bourgogne Franche-Comté, Batiment B3, Bvd Maréchal de Lattre de Tassigny, Dijon, France., Choubley H; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France; Lipidomic analytic plate-forme, Univ. Bourgogne Franche-Comté, Batiment B3, Bvd Maréchal de Lattre de Tassigny, Dijon, France., Mazzeo L; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France., Menegaut L; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France., Josiane Lebrun L; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France; AgroSup Dijon, Dijon, France., Van Dongen K; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France., Xolin M; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France., Jourdan T; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France., Buch C; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France., Labbé J; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France., Saas P; Univ. Bourgogne Franche-Comté, INSERM, EFS BFC, UMR1098, Interactions Hôte Greffon-Tumeur/Ingénierie Cellulaire et Génique, LabEx LipSTIC, Besançon, France., Lagrost L; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France; CHU Dijon, laboratoire de Biochimie, Dijon, France., Masson D; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France; CHU Dijon, laboratoire de Biochimie, Dijon, France., Grober J; Univ. Bourgogne Franche-Comté, LNC UMR12131, Dijon, France; INSERM, LNC UMR 1231, Dijon, France; FCS Bourgogne Franche-Comté, LipSTIC LabEx, Dijon, France; AgroSup Dijon, Dijon, France. Electronic address: jacques.grober@agrosupdijon.fr.

Publikováno v: Journal of lipid research [J Lipid Res] 2021; Vol. 62, pp. 100013. Date of Electronic Publication: 2020 Dec 17.