Zobrazeno 1 - 10
of 346
pro vyhledávání: '"lysine methyltransferases"'
Publikováno v:
Advanced Science, Vol 11, Iss 41, Pp n/a-n/a (2024)
Abstract Post‐translational modifications on the histone H3 tail regulate chromatin structure, impact epigenetics, and hence the gene expressions. Current chemical modulation tools, such as unnatural amino acid incorporation, protein splicing, and
Externí odkaz:
https://doaj.org/article/51630ffc0da943abb6e65b258d2a7e64
Autor:
Yiming Luo, Junli Lu, Zhen Lei, He Zhu, Dean Rao, Tiantian Wang, Chenan Fu, Zhiwei Zhang, Limin Xia, Wenjie Huang
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-21 (2024)
Abstract Lysine methylation is a crucial post-translational modification (PTM) that significantly impacts gene expression regulation. This modification not only influences cancer development directly but also has significant implications for the immu
Externí odkaz:
https://doaj.org/article/792a26f050f744609ed050e0ea22f139
Autor:
Sopita Visamol, Tanapat Palaga, Preamjit Saonanon, Vannakorn Pruksakorn, Nattiya Hirankarn, P. Martin van Hagen, Willem A. Dik, Sita Virakul
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Graves’ ophthalmopathy (GO) is an extra-thyroidal complication of Graves’ disease which can lead to vision loss in severe cases. Currently, treatments of GO are not sufficiently effective, so novel therapeutic strategies are needed. As p
Externí odkaz:
https://doaj.org/article/8dd7fca722344457ab37162a3d76d16f
Autor:
Weiwei Xu, Rui Peng, Siyu Chen, Congcong Wu, Xiaoxiao Wang, Ting Yu, Jiuying Jian, Ni Zhang, Siyang Zuo, Min Chen, Bing Guo, Lirong Liu
Publikováno v:
Pharmaceutical Biology, Vol 60, Iss 1, Pp 300-307 (2022)
Context Ranunculus ternatus Thunb (Ranunculaceae), (RTT) is used clinically for the treatment of tuberculosis or as tumour adjuvant therapy, but its potential effect on diabetic nephropathy (DN) has not been studied. Objective To investigate the effe
Externí odkaz:
https://doaj.org/article/1c3c2bc865ad46bc93aab0c7ed3098f0
Autor:
Manasi Sawant, Sadia Benamrouz-Vanneste, Dionigia Meloni, Nausicaa Gantois, Gaël Even, Karine Guyot, Colette Creusy, Erika Duval, René Wintjens, Jonathan B. Weitzman, Magali Chabe, Eric Viscogliosi, Gabriela Certad
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 1632-1650 (2022)
Cryptosporidium parvum is a leading cause of diarrhoeal illness worldwide being a significant threat to young children and immunocompromised patients, but the pathogenesis caused by this parasite remains poorly understood. C. parvum was recently link
Externí odkaz:
https://doaj.org/article/7c1f2c664a904a61bdb5ebfeabe98eaa
Akademický článek
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Akademický článek
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Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Neurodevelopmental disorders encompass a group of debilitating diseases presenting with motor and cognitive dysfunction, with variable age of onset and disease severity. Advances in genetic diagnostic tools have facilitated the identification of seve
Externí odkaz:
https://doaj.org/article/71449bf4d2024db3815b96038dbbd1e2
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Ye-Chi Cao, Su-Kang Shan, Bei Guo, Chang-Chun Li, Fu-Xing-Zi Li, Ming-Hui Zheng, Qiu-Shuang Xu, Yi Wang, Li-Min Lei, Ke-Xin Tang, Wen-Lu Ou-Yang, Jia-Yue Duan, Yun-Yun Wu, Muhammad Hasnain Ehsan Ullah, Zhi-Ang Zhou, Feng Xu, Xiao Lin, Feng Wu, Xiao-Bo Liao, Ling-Qing Yuan
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Histone methylation is an epigenetic change mediated by histone methyltransferase, and has been connected to the beginning and progression of several diseases. The most common ailments that affect the elderly are cardiovascular and cerebrovascular di
Externí odkaz:
https://doaj.org/article/bf7d9c133e9a4bc881b99339cd546eb8