Terminal deoxynucleotidyl transferase and CD84 identify human multi-potent lymphoid progenitors.

Autor: Kim Y; Immunology Graduate Program, Stanford University, Stanford, CA, USA.; Department of Pathology, Stanford University, Stanford, CA, USA., Calderon AA; Immunology Graduate Program, Stanford University, Stanford, CA, USA.; Department of Pathology, Stanford University, Stanford, CA, USA., Favaro P; Department of Pathology, Stanford University, Stanford, CA, USA., Glass DR; Immunology Graduate Program, Stanford University, Stanford, CA, USA.; Department of Pathology, Stanford University, Stanford, CA, USA., Tsai AG; Department of Pathology, Stanford University, Stanford, CA, USA., Ho D; Department of Pathology, Stanford University, Stanford, CA, USA., Borges L; Department of Pathology, Stanford University, Stanford, CA, USA., Greenleaf WJ; Department of Genetics, Stanford University, Stanford, CA, USA. wjg@stanford.edu., Bendall SC; Department of Pathology, Stanford University, Stanford, CA, USA. bendall@stanford.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Jul 13; Vol. 15 (1), pp. 5910. Date of Electronic Publication: 2024 Jul 13.

Human yolk sac-derived innate lymphoid-biased multipotent progenitors emerge prior to hematopoietic stem cell formation.

Autor: Ni Y; State Key Laboratory of Experimental Hematology, Haihe Laboratory of Cell Ecosystem, Senior Department of Hematology, Fifth Medical Center, Medical Innovation Research Department, Chinese PLA General Hospital, Beijing 100071, China., You G; School of Medicine, Tsinghua University, Beijing 100080, China., Gong Y; State Key Laboratory of Experimental Hematology, Haihe Laboratory of Cell Ecosystem, Senior Department of Hematology, Fifth Medical Center, Medical Innovation Research Department, Chinese PLA General Hospital, Beijing 100071, China., Su X; Laboratory Center, Affiliated People's Hospital of Jiangsu University, Zhenjiang 212013, China., Du Y; State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming 650031, China., Wang X; Department of Biochemistry and Molecular Biology, State Key Laboratory for Complex, Severe, and Rare Diseases, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing 100005, China., Ding X; State Key Laboratory of Experimental Hematology, Haihe Laboratory of Cell Ecosystem, Senior Department of Hematology, Fifth Medical Center, Medical Innovation Research Department, Chinese PLA General Hospital, Beijing 100071, China., Fu Q; State Key Laboratory of Experimental Hematology, Haihe Laboratory of Cell Ecosystem, Senior Department of Hematology, Fifth Medical Center, Medical Innovation Research Department, Chinese PLA General Hospital, Beijing 100071, China., Zhang M; State Key Laboratory of Experimental Hematology, Haihe Laboratory of Cell Ecosystem, Senior Department of Hematology, Fifth Medical Center, Medical Innovation Research Department, Chinese PLA General Hospital, Beijing 100071, China., Cheng T; Department of Biochemistry and Molecular Biology, State Key Laboratory for Complex, Severe, and Rare Diseases, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing 100005, China; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China; Tianjin Institutes of Health Science, Tianjin 301600, China. Electronic address: chengtao@ihcams.ac.cn., Lan Y; State Key Laboratory of Experimental Hematology, Haihe Laboratory of Cell Ecosystem Key Laboratory for Regenerative Medicine of Ministry of Education, Institute of Hematology, School of Medicine, Jinan University, Guangzhou 510632, China. Electronic address: rainyblue_1999@126.com., Liu B; State Key Laboratory of Experimental Hematology, Haihe Laboratory of Cell Ecosystem, Senior Department of Hematology, Fifth Medical Center, Medical Innovation Research Department, Chinese PLA General Hospital, Beijing 100071, China; State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming 650031, China; Department of Physiology and Pathophysiology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, China. Electronic address: bingliu17@126.com., Liu C; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China. Electronic address: liuchen@ihcams.ac.cn.

Publikováno v: Developmental cell [Dev Cell] 2024 Oct 07; Vol. 59 (19), pp. 2626-2642.e6. Date of Electronic Publication: 2024 Jul 11.

Lymphoid origin of intrinsically activated plasmacytoid dendritic cells in mice.

Autor: Araujo AM; Department of Chemical Engineering, The University of Texas at Austin, Austin, United States., Dekker JD; Department of Chemical Engineering, The University of Texas at Austin, Austin, United States., Garrison K; Department of Chemical Engineering, The University of Texas at Austin, Austin, United States., Su Z; Department of Biomedical Engineering, and Livestrong Cancer Institutes, The University of Texas at Austin, Austin, United States., Rhee C; Department of Molecular Biosciences, The University of Texas at Austin, Austin, United States., Hu Z; Department of Molecular Biosciences, The University of Texas at Austin, Austin, United States., Lee BK; Department of Molecular Biosciences, The University of Texas at Austin, Austin, United States., Osorio D; Department of Biomedical Engineering, and Livestrong Cancer Institutes, The University of Texas at Austin, Austin, United States., Lee J; Department of Chemical Engineering, The University of Texas at Austin, Austin, United States., Iyer VR; Department of Molecular Biosciences, The University of Texas at Austin, Austin, United States., Ehrlich LIR; Department of Molecular Biosciences, The University of Texas at Austin, Austin, United States., Georgiou G; Department of Molecular Biosciences, The University of Texas at Austin, Austin, United States., Ippolito G; Department of Molecular Biosciences, The University of Texas at Austin, Austin, United States., Yi S; Department of Biomedical Engineering, and Livestrong Cancer Institutes, The University of Texas at Austin, Austin, United States., Tucker HO; Department of Molecular Biosciences, The University of Texas at Austin, Austin, United States.

Publikováno v: ELife [Elife] 2024 Sep 13; Vol. 13. Date of Electronic Publication: 2024 Sep 13.

Acute leukemia of ambiguous lineage, not otherwise specified with FLT3-ITD mutation and a possible origin in the common lymphoid progenitor.

Autor: Martin-Moro F; Haematology Department, Ramón y Cajal University Hospital, Madrid, Spain., Garcia-Vela JA; Haematology Department, Puerta de Hierro University Hospital, Madrid, Spain.

Publikováno v: Cytometry. Part B, Clinical cytometry [Cytometry B Clin Cytom] 2023 Sep; Vol. 104 (5), pp. 400-403. Date of Electronic Publication: 2023 May 31.

Distinct developmental pathways generate functionally distinct populations of natural killer cells.

Autor: Ding Y; T Cell Biology and Development Unit, Laboratory of Genome Integrity, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Lavaert M; T Cell Biology and Development Unit, Laboratory of Genome Integrity, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Grassmann S; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Band VI; Metaorganism Immunity Section, Laboratory of Host Immunity and Microbiome, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Chi L; Metaorganism Immunity Section, Laboratory of Host Immunity and Microbiome, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Das A; T Cell Biology and Development Unit, Laboratory of Genome Integrity, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Das S; T Cell Biology and Development Unit, Laboratory of Genome Integrity, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Harly C; Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, Nantes, France.; LabEx IGO 'Immunotherapy, Graft Oncology', Nantes, France., Shissler SC; T Cell Biology and Development Unit, Laboratory of Genome Integrity, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Malin J; T Cell Biology and Development Unit, Laboratory of Genome Integrity, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Peng D; Molecular and Cellular Immunoregulation Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Zhao Y; T Cell Biology and Development Unit, Laboratory of Genome Integrity, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Zhu J; Molecular and Cellular Immunoregulation Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Belkaid Y; Metaorganism Immunity Section, Laboratory of Host Immunity and Microbiome, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.; NIAID Microbiome Program, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Sun JC; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Bhandoola A; T Cell Biology and Development Unit, Laboratory of Genome Integrity, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. avinash.bhandoola@nih.gov.

Publikováno v: Nature immunology [Nat Immunol] 2024 Jul; Vol. 25 (7), pp. 1183-1192. Date of Electronic Publication: 2024 Jun 13.