Výsledky vyhledávání - "lymphoblastoid cell line"

Akademický článek

Entry into the lytic cycle exposes EBV-infected cells to NK cell killing via upregulation of the MICB ligand for NKG2D and activation of the CD56bright and NKG2A+KIR+CD56dim subsets

Autor: Maria Giovanna Desimio, Daniela Angela Covino, Caterina Cancrini, Margherita Doria

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

The Epstein–Barr virus (EBV) is usually acquired during infancy as an asymptomatic infection and persists throughout life in a latent state under the control of the host immune system. However, EBV is associated with various malignant diseases that

Externí odkaz: https://doaj.org/article/79816ae48c4f432abf1b906c899172f4

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Akademický článek

Transcriptomics and miRNomics data integration in lymphoblastoid cells highlights the key role of immune-related functions in lithium treatment response in Bipolar disorder

Autor: Nadia Cattane, Cindie Courtin, Elisa Mombelli, Carlo Maj, Cristina Mora, Bruno Etain, Frank Bellivier, Cynthia Marie-Claire, Annamaria Cattaneo

Publikováno v: BMC Psychiatry, Vol 22, Iss 1, Pp 1-19 (2022)

Abstract Background Bipolar Disorder (BD) is a complex mental disease characterized by recurrent episodes of mania and depression. Lithium (Li) represents the mainstay of BD pharmacotherapy, despite the narrow therapeutic index and the high variabili

Externí odkaz: https://doaj.org/article/824ae209ccad4a448e6308dfb9cb4435

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Akademický článek

Genetic variants modulate gene expression statin response in human lymphoblastoid cell lines

Autor: Elizabeth Theusch, Yii-Der I. Chen, Jerome I. Rotter, Ronald M. Krauss, Marisa W. Medina

Publikováno v: BMC Genomics, Vol 21, Iss 1, Pp 1-18 (2020)

Abstract Background Statins are widely prescribed to lower plasma low-density lipoprotein cholesterol levels. Though statins reduce cardiovascular disease risk overall, statin efficacy varies, and some people experience adverse side effects while on

Externí odkaz: https://doaj.org/article/2518d8456eca4858ac94a0c983786e4d

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Akademický článek

SLC5A2 mutations, including two novel mutations, responsible for renal glucosuria in Chinese families

Autor: Lei Yu, Meng Wu, Ping Hou, Hong Zhang

Publikováno v: BMC Nephrology, Vol 21, Iss 1, Pp 1-8 (2020)

Abstract Background Familial renal glucosuria (FRG) is characterized by persistent glucosuria without other impairments of tubular function in the presence of normal serum glucose. SGLT2, which is almost exclusively expressed in the kidney, accounts

Externí odkaz: https://doaj.org/article/6e8d3394c1264353bb8083d598866466

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Akademický článek

Identification of the xenograft and its ascendant sphere-forming cell line as belonging to EBV-induced lymphoma, and characterization of the status of sphere-forming cells

Autor: Evgeniya V. Dolgova, Daria D. Petrova, Anastasia S. Proskurina, Genrikh S. Ritter, Polina E. Kisaretova, Ekaterina A. Potter, Yaroslav R. Efremov, Sergey I. Bayborodin, Tatiana V. Karamysheva, Margarita V. Romanenko, Sergey V. Netesov, Oleg S. Taranov, Aleksandr A. Ostanin, Elena R. Chernykh, Sergey S. Bogachev

Publikováno v: Cancer Cell International, Vol 19, Iss 1, Pp 1-21 (2019)

Abstract Background We have characterized the human cell line arised from the Epstein–Barr virus (EBV) positive multiple myeloma aspirate subjected to the long-term cultivation. This cell line has acquired the ability to form free-floating spheres

Externí odkaz: https://doaj.org/article/4d05f51831c04f3ca2868880e1361f7e

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Akademický článek

CROCIN PROMOTES APOPTOSIS IN HUMAN EBV-TRANSFORMED B-LYMPHOCYTE VIA INTRINSIC PATHWAY

Autor: Abdolreza Sotoodeh Jahromi, Mohammad Kargar, Farshid Kafilzadeh, Marzieh Jamalidoust, Maliheh Moradzadeh

Publikováno v: Mediterranean Journal of Hematology and Infectious Diseases, Vol 13, Iss 1 (2021)

Background: As a major carotenoid in saffron, crocin demonstrates potent anti-cancer impacts. However, its anti-lymphoma effects remain vague, especially in the human EBV-associated B-cell lymphoproliferative disorders. This study examined crocin's a

Externí odkaz: https://doaj.org/article/a34e084972604aac92e45cd5cf34e6c0

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Akademický článek

Genetic and genomic stability across lymphoblastoid cell line expansions

Autor: Laura B. Scheinfeldt, Kelly Hodges, Jonathan Pevsner, Dorit Berlin, Nahid Turan, Norman P. Gerry

Publikováno v: BMC Research Notes, Vol 11, Iss 1, Pp 1-5 (2018)

Abstract Objective Lymphoblastoid cell lines are widely used in genetic and genomic studies. Previous work has characterized variant stability in transformed culture and across culture passages. Our objective was to extend this work to evaluate singl

Externí odkaz: https://doaj.org/article/2917e2133b864ea4a16ec0be0fae9478

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