Water channels in the brain and spinal cord—overview of the role of aquaporins in traumatic brain injury and traumatic spinal cord injury

Autor: Thea Overgaard Wichmann, Marie Hedegaard Højsager, Helle Hasager Damkier

Publikováno v: Frontiers in Cellular Neuroscience, Vol 18 (2024)

Knowledge about the mechanisms underlying the fluid flow in the brain and spinal cord is essential for discovering the mechanisms implicated in the pathophysiology of central nervous system diseases. During recent years, research has highlighted the

Externí odkaz: https://doaj.org/article/e199489660ad48639e74f519d0fe7ac1

The involvement of perivascular spaces or tissues in the facial intradermal brain-targeted delivery

Autor: Wei Yang, Bing-Hui Jin, Ya-Jing Chen, Chang Cao, Jia-Zhen Zhu, Ying-Zheng Zhao, Xi-Chong Yu, Fan-Zhu Li

Publikováno v: Drug Delivery, Vol 26, Iss 1, Pp 393-403 (2019)

Our previous work indicates the lymphatic network and perivascular spaces or tissues might be involved in the facial intradermal brain-targeted delivery of Evans blue (EB). In this article, we presented the detailed involvement of both, and the linka

Externí odkaz: https://doaj.org/article/52a12d728ab9453ebc64cca4d7801c19

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New reporter zebrafish line unveils heterogeneity among lymphatic endothelial cells during development

Autor: Armel Houel, Nam Do Khoa, Christelle Langevin, Aurélie Lunazzi, Pierre Boudinot, Maxence Frétaud

Publikováno v: Developmental Dynamics
Developmental Dynamics, Wiley, 2021, 250 (5), pp.701-716. ⟨10.1002/dvdy.286⟩
Developmental Dynamics, 2021, 250 (5), pp.701-716. ⟨10.1002/dvdy.286⟩

Background In zebrafish, lymphatic endothelial cells (LECs) originate from multiple/several distinct progenitor populations and generate organ-specific lymphatic vasculatures. Cell fate and tissue specificities were determined using a combination of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a115957f4e8f10016f3f2f9565fbca99
https://hal.archives-ouvertes.fr/hal-03230890

Therapeutic effect of cisplatin given with a lymphatic drug delivery system on false‐negative metastatic lymph nodes

Autor: Sachiko Horie, Tetsuya Kodama, Asuka Tada, Shiro Mori

Publikováno v: Cancer Science

Systemic administration of drugs into the blood circulation is standard treatment for prevention of metastasis. However, systemic delivery cannot maintain sufficiently high concentrations of anticancer drugs in lymph nodes (LN). Here, we show that gi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994410e2bf7b5d943063991135779bfa
http://europepmc.org/articles/PMC5666029