Characterization of the cellular components of mouse collecting lymphatic vessels reveals that lymphatic muscle cells are the innate pacemaker cells regulating lymphatic contractions.

Autor: Zawieja SD; Dept. of Medical Pharmacology & Physiology, University of Missouri, Columbia, Missouri., Pea GA; Dept. of Medical Pharmacology & Physiology, University of Missouri, Columbia, Missouri., Broyhill SE; Dept. of Medical Pharmacology & Physiology, University of Missouri, Columbia, Missouri., Patro A; Dept. of Medical Pharmacology & Physiology, University of Missouri, Columbia, Missouri., Bromert KH; Dept. of Medical Pharmacology & Physiology, University of Missouri, Columbia, Missouri., Norton CE; Dept. of Medical Pharmacology & Physiology, University of Missouri, Columbia, Missouri., Kim HJ; Dept. of Medical Pharmacology & Physiology, University of Missouri, Columbia, Missouri., Sivasankaran SK; Bioinformatics and Analytics Core, Division of Research, Innovation and Impact, University of Missouri, Columbia, Missouri., Li M; Dept. of Medical Pharmacology & Physiology, University of Missouri, Columbia, Missouri., Castorena-Gonzalez JA; Dept. of Pharmacology, Tulane University, New Orleans, Louisiana., Drumm BT; Smooth Muscle Research Centre, Dundalk Institute of Technology, Dundalk, Co. Louth, A91 K584, Ireland., Davis MJ; Dept. of Medical Pharmacology & Physiology, University of Missouri, Columbia, Missouri.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 04. Date of Electronic Publication: 2024 Oct 04.

Lymphatic muscle cells contribute to dysfunction of the synovial lymphatic system in inflammatory arthritis in mice

Autor: Qianqian Liang, Li Zhang, Hao Xu, Jinlong Li, Yan Chen, Edward M. Schwarz, Qi Shi, Yongjun Wang, Lianping Xing

Publikováno v: Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-15 (2021)

Abstract Background Our previous studies reveal that impaired draining function of the synovial lymphatic vessel (LV) contributes to the pathogenesis of inflammatory arthritis, but the cellular and molecular mechanisms involved are not fully understo

Externí odkaz: https://doaj.org/article/922bebfc40e943d8946b688a7c64af4d

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Dissection of murine collecting lymphatic vessels for imaging, single-cell analysis, and tissue culture of lymphatic muscle cells

Autor: Guillermo Arroyo-Ataz, Dennis Jones

Publikováno v: STAR Protocols, Vol 3, Iss 4, Pp 101800- (2022)

Summary: In vivo and in vitro systems have the potential to provide a framework to study the organization, gene expression, and functionality of lymphatic and blood vessel smooth muscle cells in physiology and disease settings. A series of procedures

Externí odkaz: https://doaj.org/article/ce593aec658b400a9cb8549eeb874206

The Enigmas of Lymphatic Muscle Cells: Where Do They Come From, How Are They Maintained, and Can They Regenerate?

Autor: Kenney HM; Center for Musculoskeletal Research, University of Rochester Medical Center, 601 Elmwood Ave, Box 665, Rochester, NY, 14642, USA.; Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA., Peng Y; Center for Musculoskeletal Research, University of Rochester Medical Center, 601 Elmwood Ave, Box 665, Rochester, NY, 14642, USA.; Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA., de Mesy Bentley KL; Center for Musculoskeletal Research, University of Rochester Medical Center, 601 Elmwood Ave, Box 665, Rochester, NY, 14642, USA.; Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA.; Department of Orthopaedics, University of Rochester Medical Center, Rochester, NY, USA., Xing L; Center for Musculoskeletal Research, University of Rochester Medical Center, 601 Elmwood Ave, Box 665, Rochester, NY, 14642, USA.; Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA., Ritchlin CT; Center for Musculoskeletal Research, University of Rochester Medical Center, 601 Elmwood Ave, Box 665, Rochester, NY, 14642, USA.; Department of Medicine, Division of Allergy, Immunology, Rheumatology, University of Rochester Medical Center, Rochester, NY, USA., Schwarz EM; Center for Musculoskeletal Research, University of Rochester Medical Center, 601 Elmwood Ave, Box 665, Rochester, NY, 14642, USA.; Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA.; Department of Orthopaedics, University of Rochester Medical Center, Rochester, NY, USA.; Department of Medicine, Division of Allergy, Immunology, Rheumatology, University of Rochester Medical Center, Rochester, NY, USA.

Publikováno v: Current rheumatology reviews [Curr Rheumatol Rev] 2023 Jun 05; Vol. 19 (3), pp. 246-259.