Zobrazeno 1 - 10
of 1 512
pro vyhledávání: '"lung toxicity"'
Autor:
Nikos Tsolakos, Linsey E. Haswell, Fabio Miazzi, Emma Bishop, Asier Antoranz, Vaia Pliaka, Angeliki Minia, Leonidas G. Alexopoulos, Marianna Gaca, Damien Breheny
Publikováno v:
Toxicology Reports, Vol 12, Iss , Pp 492-501 (2024)
Cigarette smoking is a risk factor for several diseases such as cancer, cardiovascular disease (CVD), and chronic obstructive pulmonary diseases (COPD), however, the underlying mechanisms are not fully understood. Alternative nicotine products with r
Externí odkaz:
https://doaj.org/article/2549979cf5304ec98b71ea8e5c0999de
Autor:
Irma Mahmutovic Persson, Nina Fransén Petterson, Jian Liu, René in ‘t Zandt, Carla Carvalho, Anders Örbom, Lars E. Olsson, Karin von Wachenfeldt
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Drug-induced interstitial lung disease (ILD) is crucial to detect early to achieve the best treatment outcome. Optimally, non-invasive imaging biomarkers can be used for early detection of disease progression and treatment follow-up. Therefore, relia
Externí odkaz:
https://doaj.org/article/827e443df6da4fa3b4eb549d44709886
Publikováno v:
Cancer Medicine, Vol 12, Iss 13, Pp 13873-13884 (2023)
Abstract Objectives Anaplastic lymphoma kinase tyrosine kinase inhibitors (ALK TKIs) have shown remarkable clinical activity in patients with non‐small‐cell lung cancer (NSCLC). However, pneumonitis is a serious side effect of ALK TKIs in NSCLC p
Externí odkaz:
https://doaj.org/article/5e312b8018e44dcfb9c10b3a49a6f32c
Publikováno v:
Environment International, Vol 183, Iss , Pp 108350- (2024)
Micro/nanoplastics (MNP) are ubiquitous in the environment and multiple living organisms. The toxicity of some common types of MNP, e.g., polyethersulfone (PES) MNP, remains poorly understood. Multi-omics approaches were used in this study to determi
Externí odkaz:
https://doaj.org/article/0dd277dbcf684ce8b479ccb8c20f05c9
Autor:
Giorgio Bocchini, Maria Chiara Imperato, Tullio Valente, Salvatore Guarino, Roberta Lieto, Candida Massimo, Emanuele Muto, Federica Romano, Mariano Scaglione, Giacomo Sica, Davide Vitagliano Torre, Salvatore Masala, Marialuisa Bocchino, Gaetano Rea
Publikováno v:
Diagnostics, Vol 14, Iss 6, p 613 (2024)
Immune-checkpoint inhibitors have profoundly changed cancer treatment, improving the prognosis of many oncologic patients. However, despite the good efficacy of these drugs, their mechanism of action, which involves the activation of the immune syste
Externí odkaz:
https://doaj.org/article/84b6a9973a6b4c2fa41fd4c927446903
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 1299-1311 (2022)
The present study aimed to develop fast melting tablets (FMTs) using silymarin (SM) owing to FMTs rapid disintegration and dissolution. FMTs represent a pathway to help patients to increase their compliance level of treatment via facile administratio
Externí odkaz:
https://doaj.org/article/5819ffc427274814ab049f158491ddb2
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Nintedanib is a tyrosine kinase inhibitor of fibroblast growth factor-, vascular endothelial growth factor-, and platelet-derived growth factor receptors. These three receptors promote new blood vessel formation and maintenance, which is essential fo
Externí odkaz:
https://doaj.org/article/4dd91b510f364a12802ade4317823d2c
Autor:
Nicoletta Staropoli, Angela Salvino, Federica Falcone, Valentina Farenza, Martina Costa, Giacomo Rossini, Francesco Manti, Antonella Crispino, Caterina Riillo, Domenico Ciliberto, Mariamena Arbitrio, Pierfrancesco Tassone, Pierosandro Tagliaferri
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThe optimal strategy for the treatment of recurrent and/or advanced endometrial cancer is still undefined. Recently, despite the lack of any predictive biomarker, the combination of pembrolizumab with lenvatinib has improved survival outcom
Externí odkaz:
https://doaj.org/article/ff6871284696474fbf16f570be46d30f
Publikováno v:
Iraqi Journal of Pharmaceutical Sciences, Vol 32, Iss 1 (2023)
Cyclophosphamide (CP) is a cytotoxic alkylating agent it's used associated with different side effects including lung toxicity. Vitamin B2 and vitamin B12 have lung-protective effects. This study was designed to evaluate lung-protective effects of bo
Externí odkaz:
https://doaj.org/article/1d469d5486d948f19a6843f850cf1d5e
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