Výsledky vyhledávání - "luminal phenotype"

Akademický článek

Significance and possible causes of hormone receptor expression loss in metastatic breast cancer. Phenotypic evolution of luminal BRCA1-associated breast cancer to triple negative subtype in lung metastasis and PARP inhibition strategy in early-line therapy

Autor: A. I. Stukan, Z. K. Khachmamuk, V. V. Antipova, A. V. Dzagashtokova

Publikováno v: Опухоли женской репродуктивной системы, Vol 18, Iss 3, Pp 78-88 (2022)

Current clinical recommendations indicate the need for a biopsy of a metastatic focus in metastatic breast cancer (BC), but the optimal frequency of additional molecular analysis remains unclear. The discordance of hormonal receptors (HR) between the

Externí odkaz: https://doaj.org/article/47724076f13b4d7cb602c36160806794

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Akademický článek

Clinical and prognostic characteristics of BRCA1/2-associated breast cancer depending on the type of mutation: estrogen signaling pathway and secondary tumors

Autor: A. I. Stukan, A. Yu. Goryainova, R. A. Murashko, Z. K. Khachmamuk, O. Yu. Chukhray, S. D. Maksimenko, O. A. Goncharova, E. N. Imyanitov, V. A. Porkhanov

Publikováno v: Опухоли женской репродуктивной системы, Vol 18, Iss 2, Pp 40-52 (2022)

Background. Currently, there is growth evidence on prognostic and clinical differences in breast cancer (BC) associated with different types of BRCA1 / 2 mutations. At the same time, a triple negative tumor phenotype is not an absolute pathognomonic

Externí odkaz: https://doaj.org/article/35c68df3ee3740f284f7ebe9c9126090

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Akademický článek

Cellular and molecular determinants of all‐trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression

Autor: Floriana Centritto, Gabriela Paroni, Marco Bolis, Silvio Ken Garattini, Mami Kurosaki, Maria Monica Barzago, Adriana Zanetti, James Neil Fisher, Mark Francis Scott, Linda Pattini, Monica Lupi, Paolo Ubezio, Francesca Piccotti, Alberto Zambelli, Paola Rizzo, Maurizio Gianni', Maddalena Fratelli, Mineko Terao, Enrico Garattini

Publikováno v: EMBO Molecular Medicine, Vol 7, Iss 7, Pp 950-972 (2015)

Abstract Forty‐two cell lines recapitulating mammary carcinoma heterogeneity were profiled for all‐trans retinoic acid (ATRA) sensitivity. Luminal and ER+ (estrogen‐receptor‐positive) cell lines are generally sensitive to ATRA, while refracto

Externí odkaz: https://doaj.org/article/2b7fc1bbb9654f408b9506dd5442f5dc

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Akademický článek

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Infiltrating mast cell-mediated stimulation of estrogen receptor activity in breast cancer cells promotes the luminal phenotype

Autor: Laura Botti, Maria Teresa Majorini, Claudio Tripodo, Alice Rigoni, Mario P. Colombo, Valeria Cancila, Claudia Chiodoni, Loris De Cecco, Daniele Lecis, Enrico Fontanella, Elena Jachetti, Matteo Dugo, Tiziana Triulzi, Elda Tagliabue

Tumor growth and development is determined by both cancer cell–autonomous and microenvironmental mechanisms, including the contribution of infiltrating immune cells. Because the role of mast cells (MC) in this process is poorly characterized and ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5961be16be787af28bb8b55bc9f2933
http://hdl.handle.net/10447/414607

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Akademický článek

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Akademický článek

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Notch3 Maintains Luminal Phenotype and Suppresses Tumorigenesis and Metastasis of Breast Cancer via Trans-Activating Estrogen Receptor-α

Autor: Yao-Chen Li, Chun-Fa Chen, Jing-Wen Bai, Jie Tian, Cai-Wen Du, Yong-Qu Zhang, Guo-Jun Zhang, Hao-Yu Lin, Yuan-Ke Liang, Xiao-Long Wei, Kwan Man, Min Chen, Xiao-Wei Dou

Publikováno v: Theranostics, 7(16), 4041-4056. IVYSPRING INT PUBL
Theranostics

The luminal A phenotype is the most common breast cancer subtype and is characterized by estrogen receptor α expression (ERα). Identification of the key regulator that governs the luminal phenotype of breast cancer will clarify the pathogenic mecha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce76d300e106f7099fd52fa7446e0338
https://doi.org/10.7150/thno.19989

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Cytological Criteria for Predicting the Luminal Phenotype of Breast Carcinoma

Autor: Rozany Mucha Dufloth, Francisco Alves Moraes Neto, Fernando Schmitt, Rafael Bispo Paschoalini

Publikováno v: Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2018-11-26T17:12:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-09-01 Background: Specific cytological criteria for the luminal phenotype of breast carcinoma, despite it being the most common and having a better

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00af959427604a7cd052b0479663602b

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Dissertation/ Thesis

Critérios citológicos associados ao fenótipo luminal do carcinoma de mama

Autor: Paschoalini, Rafael Bispo [UNESP]

Publikováno v: Repositório Institucional da UNESPUniversidade Estadual PaulistaUNESP.

Submitted by Rafael Bispo Paschoalini (rbpaschoalini@gmail.com) on 2016-03-08T04:00:33Z No. of bitstreams: 1 Dissertação de mestrado - Rafael Bispo Paschoalini.pdf: 2764983 bytes, checksum: 576265167e590acb2641a540cda6283a (MD5)
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Externí odkaz: http://hdl.handle.net/11449/136187

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