Zobrazeno 1 - 10 of 271 pro vyhledávání: '"lowest observed adverse effect level"'
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Akademický článek
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Akademický článek
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4
Decreases in Concentrations and Human Dietary Intakes of Polychlorinated Biphenyls (PCBs) and Polybrominated Diphenyl Ethers (PBDEs) in Korean Seafood Between 2005 and 2017
Autor: Minkyu Choi, In-Seok Lee
Publikováno v: Archives of Environmental Contamination and Toxicology. 81:199-209
Concentrations of polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) were measured in 23 seafood species widely consumed by the Korean population in the periods of 2005–2007, 2010–2011, and 2015–2017. The Σ82PCB (sum o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1477c4d0fab4b467647bb5165688cbde
https://doi.org/10.1007/s00244-021-00860-0
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5
Determination of benchmark doses for linear furanocoumarin consumption associated with inhibition of cytochrome P450 1A2 isoenzyme activity in healthy human adults
Autor: Sabine Matou-Nasri, Zeyad Alehaideb
Publikováno v: Toxicology Reports, Vol 8, Iss, Pp 1437-1444 (2021)
Toxicology Reports
Graphical abstract
Highlights • Furanocoumarins are the main CYP1A2 inhibitors in A. majus and A. archangelica. • The inhibitory potencies appear additive to CYP1A2 activity in vitro. • BMD determination for human furanocoumarin-consumptio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df5ea20e23520f557ccf41c7273b44d
http://www.sciencedirect.com/science/article/pii/S2214750021001402
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Multigenerational reproductive assessment of 4-methylimidazole administered in the diet to Hsd:Sprague Dawley SD rats
Autor: Barry S. McIntyre, Suramya Waidyanatha, Mamta Behl, Paul M. D. Foster, Cynthia J. Willson, Sandra J. McBride, Keith R. Shockley, Katie J. Turner, Cynthia Shackelford, Helen Cunny, Chad R. Blystone
Publikováno v: Reproductive Toxicology. 98:13-28
The general population, including children and adolescents, is exposed to 4-methylimidazole (4-MI) in the diet. 4-MI is a by-product of caramel color manufacturing. It has been previously classified as a possible human carcinogen and displays potenti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872831488c5515814b324e37a797a62f
https://doi.org/10.1016/j.reprotox.2020.03.005
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Deriving individual threshold doses from clinical food challenge data for population risk assessment of food allergens
Autor: Benjamin C. Remington, Joost Westerhout, Jennifer J. Koplin, Thuy My Le, Hugh A. Sampson, W. Marty Blom, Wayne G. Shreffler, Matthew Greenhawt, René W.R. Crevel, Geert F. Houben, Montserrat Fernandez-Rivas, Jonathan O'b Hourihane, Katrina J. Allen, Anthony E.J. Dubois, Joseph L. Baumert, Barbara Ballmer-Weber, Astrid G. Kruizinga, Steve L. Taylor, Paul Turner
Publikováno v: Journal of Allergy and Clinical Immunology, 144(5), 1290. Mosby Inc.
Journal of Allergy and Clinical Immunology, 144(5), 1290-1309. MOSBY-ELSEVIER
Background: Food allergies are a significant public health issue, and the only effective management option currently available is strict avoidance of all foods containing the allergen. In view of the practical impossibility of limiting risks to zero,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d034d4b90ae64cba4e8ba97b61872c47
https://hdl.handle.net/11370/15114da8-e2b3-4f4b-bb67-fe654a91ae7d
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8
Acrylamide induces a thyroid allostasis–adaptive response in prepubertal exposed rats
Autor: Isabela Medeiros de Oliveira, Dalton Luiz Schiessel, Fernanda Ivanski, Viviane Matoso de Oliveira, Paula Bargi-Souza, Marco Romano, Renata Marino Romano
Publikováno v: Current Research in Toxicology
Current Research in Toxicology, Vol 1, Iss, Pp 124-132 (2020)
Graphical abstract
Highlights • Acrylamide acts as endocrine disruptor for the thyroid gland function. • Acrylamide increases the transcript expression of proteins related to THs synthesis. • Exposure to acrylamide alters the hypothalamus-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ade5a1f87923921749581ed3e26df6
http://europepmc.org/articles/PMC8320623
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Metabolic Consequences of Supplemented Methionine in a Clinical Context
Autor: Sunday Simbo, Mariëlle P.K.J. Engelen, Luc Cynober, Gabrie A. M. Ten Have, Gerdien C. Ligthart-Melis, J.J. Thaden, Nicolaas E. P. Deutz
Publikováno v: The Journal of Nutrition. 150:2538S-2547S
The central position of methionine (Met) in protein metabolism indicates the importance of this essential amino acid for growth and maintenance of lean body mass. Therefore, Met might be a tempting candidate for supplementation. However, because Met
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d28d41531339c356523491fd3885ed
https://doi.org/10.1093/jn/nxaa254
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Assessment of Surface Drinking Water Resources of Turkey in Terms of Water Quality Standards
Autor: Bülent Selek
Publikováno v: Journal of Water Chemistry and Technology. 42:415-426
Monitoring and assessment of surface drinking water resources is vital for human life. As it is known, many diseases are caused by contaminated waters. Surface water resources quality was classified in terms of treatment potential by using 41 convent
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9dc5d3674ae87f73d494d018d4c7ddba
https://doi.org/10.3103/s1063455x20050124
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