Zobrazeno 1 - 10
of 419
pro vyhledávání: '"lower-grade gliomas"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Lower-grade gliomas (LGGs) exhibit highly variable clinical behaviors, while classic histology characteristics cannot accurately reflect the authentic biological behaviors, clinical outcomes, and prognosis of LGGs. In this study, we carried
Externí odkaz:
https://doaj.org/article/53d5451431eb45a5b7a269f209755ac2
Autor:
C.S. Byskov, A. Muhic, R.H. Dahlrot, C.A. Haslund, T.L. Guldberg, M. Høyer, P.W. Nyström, L. Dysager, S. Hansen, L. Haldbo-Classen, A.K. Trip, Y. Lassen-Ramshad, B. Weber, S. Lukacova, C.R. Hansen, J.F. Kallehauge
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 48, Iss , Pp 100836- (2024)
Background: For adult patients with grade 1–3 gliomas, identifying patients with an indication for proton therapy (PT) can be challenging due to sparse evidence supporting its benefits. In this study, we aimed to ensure national consensus and devel
Externí odkaz:
https://doaj.org/article/d62256c31fee4ff1ab0cd10b36b11821
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionThe tumor microenvironment and IRGs are highly correlated with tumor occurrence, progression, and prognosis. However, their roles in grade II and III gliomas, termed LGGs in this study, remain to be fully elucidated. Our research aims to
Externí odkaz:
https://doaj.org/article/2f5f5a58c4d3455da480728d20e3c7df
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Temozolomide (TMZ) has been used as a first-line therapy against lower-grade gliomas (LGGs) combined with other chemotherapy drugs. However, there has been no reliable index predicting TMZ response of patients with LGGs. In this study, we ai
Externí odkaz:
https://doaj.org/article/bab9a06daa93436191f9ee003e481694
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-18 (2023)
Abstract Background As a component of membrane lipids and the precursor of oxysterols and steroid hormones, reprogrammed cholesterol metabolism contributes to the initiation and progression of multiple cancers. Thus, we aim to further investigate the
Externí odkaz:
https://doaj.org/article/68fb54f9aed94109abf28c34e085b4a1
Autor:
Yanwei Liu, Huiyuan Chen, Guanzhang Li, Jing Zhang, Kun Yao, Chenxing Wu, Shouwei Li, Xiaoguang Qiu
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 10, Pp 1477-1486 (2022)
Objective: IDH-mutant lower-grade gliomas (LGGs, grade 2 or 3) eventually transform into secondary grade 4 astrocytomas (sAIDHmut/G4). Here, we sought to describe the transformation time, risk factors, and outcomes in malignant transformation of IDH-
Externí odkaz:
https://doaj.org/article/da7ca752161c4d66915622d91f1cb1b5
Autor:
Feng Yuan, Yingshuai Wang, Xiangming Cai, Chaonan Du, Junhao Zhu, Chao Tang, Jin Yang, Chiyuan Ma
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 3, Iss 5, Pp 553-569 (2022)
Aim: Lower grade gliomas [LGGs; World Health Organization (WHO) grades 2 and 3], owing to the heterogeneity of their clinical behavior, present a therapeutic challenge to neurosurgeons. The aim of this study was to explore the N6-methyladenosine (m6A
Externí odkaz:
https://doaj.org/article/e80c5ce1fdf243b5b48977369cd77935
Akademický článek
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Publikováno v:
Cancer Medicine, Vol 11, Iss 9, Pp 2020-2035 (2022)
Abstract Background The therapeutic effects of conventional treatment on gliomas are not promising. The tumor microenvironment (TME) has a close association with the invasiveness of multiple types of tumors, including low‐grade gliomas (LGG). This
Externí odkaz:
https://doaj.org/article/d36431d2f89f48848cba78cec659bf8e
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
FDX1 participates in cuproptosis, a copper-dependent cell death mode, which might influence tumor progressions like ferroptosis and pyroptosis. However, the role of FDX1 in tumors remains to be explored. This study investigated FDX1 expression featur
Externí odkaz:
https://doaj.org/article/8d1aaca61a514259b1774f113b2bce38