Zobrazeno 1 - 10
of 184
pro vyhledávání: '"low-grade serous ovarian cancer"'
Autor:
Asim Leblebici, Ceren Sancar, Bahar Tercan, Zerrin Isik, Mehmet Emin Arayici, Ender Berat Ellidokuz, Yasemin Basbinar, Nuri Yildirim
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 3, Pp 1777-1798 (2024)
This paper aims to elucidate the differentially coexpressed genes, their potential mechanisms, and possible drug targets in low-grade invasive serous ovarian carcinoma (LGSC) in terms of the biologic continuity of normal, borderline, and malignant LG
Externí odkaz:
https://doaj.org/article/d39fdfba774f46989b253c183d920e34
Autor:
Shashank Sama, Sterling Rosqvist, Talicia Savage, Lesley Lomo, Kiera Sibbald, Alli Straubhar, Theresa L. Werner
Publikováno v:
Gynecologic Oncology Reports, Vol 53, Iss , Pp 101412- (2024)
Low grade serous ovarian cancers (LGSOC) in an advanced setting have limited systemic treatment options. In this paper we report a case of metastatic LGSOC harboring a BRAF mutation, treated with dabrafenib. We discuss the clinical, pathologic and mo
Externí odkaz:
https://doaj.org/article/4409c5afb5dc4e5bb35d4713ce930f60
Autor:
Caitlin Lazurko, Revital Linder, Kate Pulman, Genevieve Lennox, Tomer Feigenberg, Rouhi Fazelzad, Taymaa May, Tiffany Zigras
Publikováno v:
Current Oncology, Vol 30, Iss 9, Pp 8159-8171 (2023)
Serous epithelial ovarian cancer, classified as either high-grade (90%) or low-grade (10%), varies in molecular, histological, and clinicopathological presentation. Low-grade serous ovarian cancer (LGSOC) is a rare histologic subtype that lacks disea
Externí odkaz:
https://doaj.org/article/48278b6557e24405916fa8efc993d06c
Autor:
Marwah Al-Aloosi, Amanda M. Prechtl, Payel Chatterjee, Brady Bernard, Christopher J. Kemp, Rachele Rosati, Robert L. Diaz, Lauren R. Appleyard, Shalini Pereira, Alex Rajewski, Amber McDonald, Eva J. Gordon, Carla Grandori
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
Patients presenting with stage 4 ovarian carcinoma, including low-grade serous disease, have a poor prognosis. Although platinum-based therapies can offer some response, these therapies are associated with many side effects, and treatment resistance
Externí odkaz:
https://doaj.org/article/fcc76ebb292445b4b3f929be800bb6b7
Autor:
Kwong-Kwok Wong, Nicholas W. Bateman, Chun Wai Ng, Yvonne T. M. Tsang, Charlotte S. Sun, Joseph Celestino, Tri V. Nguyen, Anais Malpica, R. Tyler Hillman, Jianhua Zhang, P. Andrew Futreal, Christine Rojas, Kelly A. Conrads, Brian L. Hood, Clifton L. Dalgard, Matthew D. Wilkerson, Neil T. Phippen, Thomas P. Conrads, George L. Maxwell, Anil K. Sood, David M. Gershenson
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Low-grade serous ovarian cancer (LGSOC) is a rare disease that occurs more frequently in younger women than those with high-grade disease. The current treatment is suboptimal and a better understanding of the molecular pathogenesi
Externí odkaz:
https://doaj.org/article/3d3ade2fb20a4c199fb227538f7a10f6
Publikováno v:
Journal of Education, Health and Sport, Vol 31, Iss 1 (2023)
Introduction: Low-grade serous ovarian cancer (LGSOC) accounting for less than 10% of all serous ovary cancers. The chemoresistance inherent to this type of ovarian cancer narrows the therapeutic options, especially in the recurrent setting. It is th
Externí odkaz:
https://doaj.org/article/d7fba97e72fb4b73b9c86692771ef4a6
Autor:
Paolo Di Lorenzo, Vincenza Conteduca, Emanuela Scarpi, Marco Adorni, Francesco Multinu, Annalisa Garbi, Ilaria Betella, Tommaso Grassi, Tommaso Bianchi, Giampaolo Di Martino, Andrea Amadori, Paolo Maniglio, Isabella Strada, Silvestro Carinelli, Marta Jaconi, Giovanni Aletti, Vanna Zanagnolo, Angelo Maggioni, Luca Savelli, Ugo De Giorgi, Fabio Landoni, Nicoletta Colombo, Robert Fruscio
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Simple summaryLow-grade serous ovarian cancer (LGSOC) represents an uncommon histotype of serous ovarian cancer (accounting for approximately 5% of all ovarian cancer) with a distinct behavior compared to its high-grade serous counterpart, characteri
Externí odkaz:
https://doaj.org/article/8e1e191bdf904bd3aed14edd63a78c00
Autor:
Zhongshao Chen, Ran Chu, Yuanming Shen, Qin Yao, Jingying Chen, Tianyu Qin, Li Li, Gang Chen, Qinglei Gao, Chaoyang Sun, Li Song, Junting Li, Penglin Liu, Xiyu Pan, Jingnan Li, Xiaoying Zhu, Li Zhang, Xu Qiao, Ding Ma, Beihua Kong, Kun Song
Publikováno v:
Translational Oncology, Vol 23, Iss , Pp 101476- (2022)
Background: The prognostic value of lymphadenectomy in low-grade serous ovarian cancer (LGSOC) remains uncertain. Materials and methods: A retrospective analysis of 155 patients with LGSOC who underwent surgery over a ten-year period (2011–2020) wa
Externí odkaz:
https://doaj.org/article/492a9bf55a054f5794b33a2bff828c03
Autor:
Tanja Pejovic, Pierre-Valérien Abate, Hongli Ma, Jaclyn Thiessen, Christopher L. Corless, Abigail Peterson, Hugues Allard-Chamard, Marilyne Labrie
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Between 2% and 6% of epithelial ovarian cancer (EOC) patients develop brain metastases (brain mets), which are incurable and invariably result in death. This poor outcome is associated with a lack of established guidelines for the detection and treat
Externí odkaz:
https://doaj.org/article/ab4da7bdcfef4039a8cdb4d84839ed1d
Autor:
Bengt Tholander, Anthoula Koliadi, Johan Botling, Hanna Dahlstrand, Anne Von Heideman, Håkan Ahlström, Kjell Öberg, Gustav J. Ullenhag
Publikováno v:
Upsala Journal of Medical Sciences, Vol 125, Iss 4, Pp 325-329 (2020)
More effective treatments are needed for low-grade serous ovarian carcinoma (LGSOC). Our patient, who suffers from metastatic LGSOC, had received all established treatments. Sequencing analysis revealed an activating BRAF mutation. Therefore, combine
Externí odkaz:
https://doaj.org/article/c4b453e61d4241608c632329d5ead8b1