Zobrazeno 1 - 10
of 3 195
pro vyhledávání: '"long‐read sequencing"'
Autor:
Amy L. Toth, Christopher D. R. Wyatt, Rick E. Masonbrink, Katherine S. Geist, Ryan Fortune, Sarah B. Scott, Emeline Favreau, Sandra M. Rehan, Seirian Sumner, Mary M. Gardiner, Frances S. Sivakoff
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background The common Eastern bumble bee Bombus impatiens is native to North America and is the main commercially reared pollinator in the Americas. There has been extensive research on this species related to its social biology, applied pol
Externí odkaz:
https://doaj.org/article/d3eaa7d32c304cd5b06b4659e06a3c91
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Metagenomic analysis has enabled insights into soil community structure and dynamics. Long-read sequencing for metagenomics can enhance microbial ecology by improving taxonomic classification, genome assembly, and functional annotation. Howe
Externí odkaz:
https://doaj.org/article/72249bb7a3be42a0aa215f9444af52bc
Autor:
Worarat Kruasuwan, Pongpun Sawatwong, Piroon Jenjaroenpun, Natnicha Wankaew, Tantip Arigul, Suganya Yongkiettrakul, Kamonwan Lunha, Aunthikarn Sudjai, Duangkamon Siludjai, Beth Skaggs, Thidathip Wongsurawat
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The advent of Oxford Nanopore Technologies has undergone significant improvements in terms of sequencing costs, accuracy, and sequencing read lengths, making it a cost-effective, and readily accessible approach for analyzing microbial genome
Externí odkaz:
https://doaj.org/article/ca888cb84cf74709b4358a9e03b937e1
Autor:
Barbara Slapnik, Robert Šket, Klementina Črepinšek, Tine Tesovnik, Barbara Jenko Bizjan, Jernej Kovač
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract This study evaluates long-read and short-read sequencing for mitochondrial DNA (mtDNA) heteroplasmy detection. 592,315 bootstrapped datasets generated from two single-nucleotide mismatched ultra-deep sequenced mtDNA samples were used to asse
Externí odkaz:
https://doaj.org/article/82b7807f8a204fae9861eef7fd4647dd
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-6 (2024)
Abstract Telomeres are protective structures at the end of eukaryotic chromosomes that are strongly implicated in ageing and ill health. They attrition upon every cellular reproductive cycle. Evidence suggests that short telomeres trigger DNA damage
Externí odkaz:
https://doaj.org/article/5df8233f4ebd40fb8f7507413dcecee5
Autor:
Leire Urrutia-Angulo, Medelin Ocejo, Beatriz Oporto, Gorka Aduriz, José Luís Lavín, Ana Hurtado
Publikováno v:
Animal Microbiome, Vol 6, Iss 1, Pp 1-14 (2024)
Abstract Background Mastitis, inflammation of the mammary gland, is a major disease of dairy cattle and the main cause for antimicrobial use. Although mainly caused by bacterial infections, the aetiological agent often remains unidentified by convent
Externí odkaz:
https://doaj.org/article/b794b8a8e07b49c382261ac9b01917a8
Autor:
Wenjie Xia, Dawei Chen, Xinnian Li, Jing Liu, Xiuzhang Xu, Xin Ye, Jing Deng, Haoqiang Ding, Hui Ren, Yangkai Chen, Huaqin Liang, Xingqiang Lai, Yongshui Fu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract CD36, also known as glycoprotein IV, is classified into two distinct subgroups based on the presence or absence of its expression on monocytes. The CD36 gene spans approximately 50,000 base pairs. Historically, research has focused on identi
Externí odkaz:
https://doaj.org/article/2a7f51e739584f06ada434813f25ec82
Autor:
Jidong Liu, Huihui Tian, Xinchen Jin, Yanxiang Wang, Zhenhong Zhang, Mengxue Li, Lulu Dai, Xiaoli Zhang, Ling Jiang
Publikováno v:
BMC Endocrine Disorders, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background 11β-hydroxylase deficiency (11β-OHD), caused by homozygosity or compound heterozygosity CYP11B1 variants, is the second most common cause of congenital adrenal hyperplasia (CAH). Due to the high degree of sequence identity betwe
Externí odkaz:
https://doaj.org/article/181d36ce8cd346c38ad49fe735fa276f
Autor:
Kai Yee Toh, Tzi Shin Toh, Khi Pin Chua, Priscilla Rajakumar, Jonathan Wei Jie Lee, Chun Wie Chong
Publikováno v:
Gut Pathogens, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Background Age-related gut microbial changes have been widely investigated over the past decade. Most of the previous age-related microbiome studies were conducted on the Western population, and the short-read sequencing (e.g., 16S V4 or V3-
Externí odkaz:
https://doaj.org/article/dc19c4299ea84b65af71ec21ef994c2f
Autor:
Lingchen Liu, Jia Zhang, Scott Wood, Felicity Newell, Conrad Leonard, Lambros T. Koufariotis, Katia Nones, Andrew J. Dalley, Haarika Chittoory, Farzad Bashirzadeh, Jung Hwa Son, Daniel Steinfort, Jonathan P. Williamson, Michael Bint, Carl Pahoff, Phan T. Nguyen, Scott Twaddell, David Arnold, Christopher Grainge, Peter T. Simpson, David Fielding, Nicola Waddell, John V. Pearson
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Lung cancer is a heterogeneous disease and the primary cause of cancer-related mortality worldwide. Somatic mutations, including large structural variants, are important biomarkers in lung cancer for selecting targeted therapy. Ge
Externí odkaz:
https://doaj.org/article/3e541a9800144058a28c32a39366caaa