Survey of the impact of BOLT-trial data on oncologists’ and dermatologists’ decision-making in treating patients with locally advanced basal cell carcinoma

Autor: Luigi Scarpato, Marco Palla, Sabino Strippoli, Luca Tagliaferri, Luca Fania, Maristella Saponara, Anna Carbone, Francesco Spagnolo, Flavia Silvestri, Paolo Antonio Ascierto

Publikováno v: Dermatology Reports (2024)

Basal cell carcinoma (BCC) is the most common malignant tumour in white populations. Multiple studies demonstrated that the aberrant activation of Hedgehog signaling is a driver of BCC development, and its blockade represents a potential therapeutic

Externí odkaz: https://doaj.org/article/532de72c851f4cdb8b02316ca70fc097

Vismodegib-resistant basal cell carcinomas in basal cell nevus syndrome: Clinical approach and genetic analysis

Autor: Kelly A.E. Sinx, Ernst-Jan M. Speel, Virrie van Zutven, Michel van Geel, P.M. Steijlen, Renske Janssen, Guido M.J.M. Roemen, Klara Mosterd

Publikováno v: JAAD Case Reports, 4(5), 408-11. Elsevier Inc.
JAAD Case Reports

Basal cell nevus syndrome (BCNS, Gorlin syndrome) is a rare inherited disorder characterized by the development of multiple basal cell carcinomas (BCCs), odontogenic keratocysts, and palmar pits.1 BCC development is caused by sonic hedgehog pathway (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a9e4ff75fb9b9aa0e5b64c564ad5bd
https://doi.org/10.1016/j.jdcr.2017.11.011

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Vismodegib-resistant basal cell carcinomas in basal cell nevus syndrome: Clinical approach and genetic analysis.

Autor: Sinx KAE; Department of Dermatology, Maastricht University Medical Centre, Maastricht, The Netherlands.; GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands., Roemen GMJM; Department of Pathology, Maastricht University Medical Centre, Maastricht, The Netherlands., van Zutven V; Department of Dermatology, Maastricht University Medical Centre, Maastricht, The Netherlands., Janssen R; Department of Dermatology, Maastricht University Medical Centre, Maastricht, The Netherlands.; GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands., Speel EM; GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.; Department of Pathology, Maastricht University Medical Centre, Maastricht, The Netherlands., Steijlen PM; Department of Dermatology, Maastricht University Medical Centre, Maastricht, The Netherlands.; GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands., van Geel M; Department of Dermatology, Maastricht University Medical Centre, Maastricht, The Netherlands.; GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.; Department of Clinical Genetics, Maastricht University Medical Centre, Maastricht, The Netherlands., Mosterd K; Department of Dermatology, Maastricht University Medical Centre, Maastricht, The Netherlands.; GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.

Publikováno v: JAAD case reports [JAAD Case Rep] 2018 Apr 30; Vol. 4 (5), pp. 408-411. Date of Electronic Publication: 2018 Apr 30 (Print Publication: 2018).