Zobrazeno 1 - 10
of 76
pro vyhledávání: '"local drug delivery system"'
Publikováno v:
In Journal of Controlled Release February 2024 366:160-169
Publikováno v:
Materials & Design, Vol 199, Iss , Pp 109429- (2021)
Fatty acid-based in situ forming systems that carry vancomycin HCl (VCM) have been developed to treat local Gram-positive infections. However, little is known about mechanistic formation of fat-based in situ forming matrices. In this study, VCM-loade
Externí odkaz:
https://doaj.org/article/1a07d0e2368f4068abcdaa8e74a08dcb
Autor:
Toshiya Morozumi, Yohei Nakayama, Satoshi Shirakawa, Kentaro Imamura, Kaname Nohno, Takatoshi Nagano, Haruna Miyazawa, Takahiro Hokari, Ryo Takuma, Shuntaro Sugihara, Kazuhiro Gomi, Atsushi Saito, Yorimasa Ogata, Motohiro Komaki
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 719 (2022)
This prospective pilot study aimed to evaluate the effect of minocycline-HCl ointment (MO), locally delivered as an adjunct to scaling and root planing (SRP), on subgingival microflora. A total of 59 periodontitis patients received SRP as an initial
Externí odkaz:
https://doaj.org/article/b55d527144da48b5a59580343692db7c
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1069 (2022)
Titanium and its alloys are the most widely applied orthopedic and dental implant materials due to their high biocompatibility, superior corrosion resistance, and outstanding mechanical properties. However, the lack of superior osseointegration remai
Externí odkaz:
https://doaj.org/article/4f6200e2fadb4da2acb90feab44c53e3
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 13, Iss 1, Pp 1-11 (2018)
Abstract Implant-related infections (IRIs) which led to a large amount of medical expenditure were caused by bacteria and fungi that involve the implants in the operation or in ward. Traditional treatments of IRIs were comprised of repeated radical d
Externí odkaz:
https://doaj.org/article/0934549c95c448afb1bcd19dbcbaf98e
Autor:
Xiao Ma, Yun Gao, Duoyi Zhao, Weilin Zhang, Wei Zhao, Meng Wu, Yan Cui, Qin Li, Zhiyu Zhang, Chengbin Ma
Publikováno v:
Nanomaterials, Vol 12, Iss 1, p 47 (2021)
Titanium implants have always been regarded as one of the gold standard treatments for orthopedic applications, but they still face challenges such as pain, bacterial infections, insufficient osseointegration, immune rejection, and difficulty in pers
Externí odkaz:
https://doaj.org/article/b74b12a8f4f6410fab8cce75ce8dad9a
Autor:
Youngbum Yoo, Sun-Jung Yoon, So Yeon Kim, Deok-Won Lee, Sewook Um, Hoon Hyun, Sung Ok Hong, Dae Hyeok Yang
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 1664-1671 (2018)
Systemic drug delivery systems (SDDSs) for thyroid cancer treatment are associated with serious side effects including nausea, anorexia, and hair loss as a result of damage to normal tissues. In this study, we investigated the feasibility of a local
Externí odkaz:
https://doaj.org/article/1a7677588f3c467bbe48815bf5cc9173
Publikováno v:
Indian Journal of Dental Research, Vol 27, Iss 1, Pp 15-21 (2016)
Introduction: Anti-microbial therapy is essential along with conventional therapy in the management of periodontal disease. Instead of systemic chemical agents, herbal products could be used as antimicrobial agents. Herbal local drug delivery systems
Externí odkaz:
https://doaj.org/article/c047e0b085dc4db2abdf63bfb7b4f83f
Autor:
Isabela da Rocha Silva, Aline Tavares da Silva Barreto, Renata Santos Seixas, Paula Nunes Guimarães Paes, Juliana do Nascimento Lunz, Rossana Mara da Silva Moreira Thiré, Paula Mendes Jardim
Publikováno v:
Materials; Volume 16; Issue 7; Pages: 2755
The topography and chemical composition modification of the titanium (Ti) implants play a decisive role in improving biocompatibility and bioactivity, accelerating osseointegration, and, thus, determining clinical success. In spite of the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f7f8c3ec45f69988db1d3d5d5d1f7c
Publikováno v:
Nanomaterials, Vol 9, Iss 12, p 1652 (2019)
Osteosarcoma (OSA) is a difficult cancer to treat due to its tendency for relapse and metastasis; advanced methods are therefore required for OSA treatment. In this study, we prepared a local drug-delivery system for OSA treatment based on doxorubici
Externí odkaz:
https://doaj.org/article/d74fe2711dda45f19bfb6fa39dbb2c15