Zobrazeno 1 - 10
of 51
pro vyhledávání: '"lncRNA similarity"'
Publikováno v:
IEEE Access, Vol 8, Pp 111614-111625 (2020)
Recent studies indicated that numerous long noncoding RNAs (lncRNAs) are closely related to human diseases and can serve as potential biomarkers and drug targets for complex diseases. Therefore, identifying lncRNAs associated with diseases through co
Externí odkaz:
https://doaj.org/article/3de5a76b4fdd480fa2f90d59e57ad24f
Publikováno v:
IEEE Access, Vol 8, Pp 26190-26198 (2020)
In recent years, it has been increasingly clear that long non-coding RNAs (lncRNAs) are able to regulate their target genes at multi-levels, including transcriptional level, translational level, etc and play key regulatory roles in many important bio
Externí odkaz:
https://doaj.org/article/c1cceb90a7fc4854ae85609373938db9
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Long noncoding RNA (lncRNA), a type of more than 200 nucleotides non-coding RNA, is related to various complex diseases. To precisely identify the potential lncRNA–disease association is important to understand the disease pathogenesis, to develop
Externí odkaz:
https://doaj.org/article/35cf52e337e845ca85f908dd473413a6
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Long non-coding RNAs (lncRNAs) are widely concerned because of their close associations with many key biological activities. Though precise functions of most lncRNAs are unknown, research works show that lncRNAs usually exert biological function by i
Externí odkaz:
https://doaj.org/article/73cc32f22773426182a1ca3129aef3f9
Publikováno v:
BMC Medical Genomics, Vol 10, Iss S5, Pp 67-74 (2017)
Abstract Background Similar diseases are always caused by similar molecular origins, such as diasease-related protein-coding genes (PCGs). And the molecular associations reflect their similarity. Therefore, current methods for calculating disease sim
Externí odkaz:
https://doaj.org/article/a95339bba6d5472cb883c5d03c783d90
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Evidences increasingly indicate the involvement of long non-coding RNAs (lncRNAs) in various biological processes. As the mutations and abnormalities of lncRNAs are closely related to the progression of complex diseases, the identification of lncRNA-
Externí odkaz:
https://doaj.org/article/aa3932ee028c4480b117dbace6184902
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1508 (2020)
Long non-coding RNAs (long ncRNAs, lncRNAs) of all kinds have been implicated in a range of cell developmental processes and diseases, while they are not translated into proteins. Inferring diseases associated lncRNAs by computational methods can be
Externí odkaz:
https://doaj.org/article/e507dbeadce84db18c24c9301e8e93b9
Autor:
Xiaofang Xiao, Wen Zhu, Bo Liao, Junlin Xu, Changlong Gu, Binbin Ji, Yuhua Yao, Lihong Peng, Jialiang Yang
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
In recent years, it has been increasingly clear that long noncoding RNAs (lncRNAs) play critical roles in many biological processes associated with human diseases. Inferring potential lncRNA-disease associations is essential to reveal the secrets beh
Externí odkaz:
https://doaj.org/article/4e57c99cd44549d3a9c3eb743349a77b
Publikováno v:
IEEE Access, Vol 8, Pp 111614-111625 (2020)
Recent studies indicated that numerous long noncoding RNAs (lncRNAs) are closely related to human diseases and can serve as potential biomarkers and drug targets for complex diseases. Therefore, identifying lncRNAs associated with diseases through co
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 18, Iss, Pp 45-55 (2019)
Molecular Therapy: Nucleic Acids, Vol 18, Iss, Pp 45-55 (2019)
Recently, prediction of lncRNA-disease associations has attracted more and more attentions. Various computational models have been proposed; however, there is still room to improve the prediction accuracy. In this paper, we propose a kernel fusion me