Zobrazeno 1 - 10
of 327
pro vyhledávání: '"liver stem cells"'
Autor:
Fei Chen, Kunshan Zhang, Minjun Wang, Zhiying He, Bing Yu, Xin Wang, Xinghua Pan, Yuping Luo, Shoujia Xu, Joseph T.Y. Lau, Chunsheng Han, Yufang Shi, Yi E. Sun, Siguang Li, Yi‐Ping Hu
Publikováno v:
Advanced Science, Vol 11, Iss 33, Pp n/a-n/a (2024)
Abstract Understanding the liver stem cells (LSCs) holds great promise for new insights into liver diseases and liver regeneration. However, the heterogenicity and plasticity of liver cells have made it controversial. Here, by employing single‐cell
Externí odkaz:
https://doaj.org/article/8529960fe08c4012bfdbf1dc61c5d470
Autor:
Giulia Chiabotto, Elena Ceccotti, Chiara Pasquino, Maria Beatriz Herrera Sanchez, Massimo Cedrino, Giovanni Camussi, Stefania Bruno
Publikováno v:
Exploration of Digestive Diseases, Vol 2, Iss 4, Pp 172-187 (2023)
Aim: Modifications in long non-coding RNA (lncRNA) expression are associated with inflammation and fibrosis in chronic liver diseases. It has been recently demonstrated that human liver stem cells (HLSCs) and their extracellular vesicles (EVs) can ef
Externí odkaz:
https://doaj.org/article/fc4a7c245b0f4b2396f894e3a30dca36
Autor:
Marta Tapparo, Gabriele Saccu, Chiara Pasquino, Valentina Fonsato, Claudio Medana, Valentina Schiavo, Enrica Mecarelli, Monica Maccagno, Lorenzo Silengo, Stefania Bruno, Giovanni Camussi, Maria Beatriz Herrera Sanchez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Introduction: The lack of functional hepatocytes poses a significant challenge for drug safety testing and therapeutic applications due to the inability of mature hepatocytes to expand and their tendency to lose functionality in vitro. Previous studi
Externí odkaz:
https://doaj.org/article/2297f9d0135249cba1b41372e9ebb979
Publikováno v:
JHEP Reports, Vol 5, Iss 8, Pp 100779- (2023)
Summary: The process of metabolic liver zonation is spontaneously established by assigning distributed tasks to hepatocytes along the porto-central blood flow. Hepatocytes fulfil critical metabolic functions, while also maintaining hepatocyte mass by
Externí odkaz:
https://doaj.org/article/7dd3870b7df1449eb677ddd96ce0060c
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1715 (2023)
Renal pathophysiology is a multifactorial process involving different kidney structures. Acute kidney injury (AKI) is a clinical condition characterized by tubular necrosis and glomerular hyperfiltration. The maladaptive repair after AKI predisposes
Externí odkaz:
https://doaj.org/article/8c2d0b496da44a9786f727d2892d3e3c
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 273-290 (2021)
Epithelial cells in the liver (known as hepatocytes) are high-performance engines of myriad metabolic functions and versatile responders to liver injury. As hepatocytes metabolize amino acids, alcohol, drugs, and other substrates, they produce and ar
Externí odkaz:
https://doaj.org/article/8cbd639ed031408ca7c8ee10358e1593
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Di-san junyi daxue xuebao, Vol 41, Iss 24, Pp 2417-2424 (2019)
Objective To investigate the effect of overexpression of ATPase family AAA domain protein 3A (ATAD3A) on epithelial-to-mesenchymal transition (EMT), migration and invasion of rat liver stem cells. Methods Cultured rat liver stem cell line (WBF-344) w
Externí odkaz:
https://doaj.org/article/52d4feff19b841c3b98f2d468b1bf7b4
Autor:
Yanzhen Bi, Jiannan Li, Yonghong Yang, Quanyi Wang, Quanquan Wang, Xiaobei Zhang, Guanjun Dong, Yibo Wang, Zhongping Duan, Zhenfeng Shu, Tongjun Liu, Yu Chen, Kai Zhang, Feng Hong
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-11 (2019)
Abstract Background Acute liver failure (ALF) is a serious threat to the life of people all over the world. Finding an effective way to manage ALF is important. Human liver stem cells (HLSCs) are early undifferentiated cells that have been implicated
Externí odkaz:
https://doaj.org/article/cb0d9a50e1bd4272ba57f57be16f0467