Colorectal cancer-derived small extracellular vesicles induce TGFβ1-mediated epithelial to mesenchymal transition of normal hepatocytes: new insights on pre-metastatic niche formation in the liver

Autor: URZI', Ornella

More than 50% of patients affected by colorectal cancer (CRC) present liver metastasis, which is the most frequent cause of CRC-associated death. Numerous studies have shown that metastatic cascade is the result of complex mechanisms based on two-way

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3658::e9e1c45caf044dea526d73dcbed4c7d4
https://hdl.handle.net/10447/594833

Improving Outcome of Selected Patients With Non-Resectable Hepatic Metastases From Colorectal Cancer With Liver Transplantation: A Prospective Parallel Trial (COLT trial)

Autor: Carlo Sposito, Filippo Pietrantonio, Marianna Maspero, Fabrizio Di Benedetto, Marco Vivarelli, Giuseppe Tisone, Luciano De Carlis, Renato Romagnoli, Salvatore Gruttadauria, Michele Colledan, Salvatore Agnes, Giuseppe Ettorre, Umberto Baccarani, Guido Torzilli, Stefano Di Sandro, Domenico Pinelli, Lucio Caccamo, Andrea Sartore Bianchi, Carlo Spreafico, Valter Torri, Vincenzo Mazzaferro

Background: Patients with unresectable Colorectal Liver Metastases (CLM) receiving palliative chemotherapy have a 5-year overall survival (OS) of less than 30%. Liver transplantation (LT) can improve OS up to 60%-83% (SECA-I and SECA-II trials). The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cb88be41f8f91741edf1a0ab00594f
https://hdl.handle.net/10281/409736

Simultaneous pelvic exenteration and liver resection for primary rectal cancer with synchronous liver metastases: results from the PelvEx Collaborative

Autor: Kelly, M. E., Aalbers, A. G. J., Abdul Aziz, N., Abecasis, N., Abraham‐Nordling, M., Akiyoshi, T., Alberda, W., Albert, M., Andric, M., Angenete, E., Antoniou, A., Auer, R., Austin, K. K., Aziz, O., Baker, R. P., Bali, M., Baseckas, G., Bebington, B., Bednarski, B. K., Beets, G. L., Berg, P. L., Beynon, J., Biondo, S., Boyle, K., Bordeianou, L., Bremers, A. B., Brunner, M., Buchwald, P., Bui, A., Burgess, A., Burger, J. W. A., Burling, D., Burns, E., Campain, N., Carvalhal, S., Castro, L., Caycedo‐Marulanda, A., Chan, K. K. L., Chang, G. J., Chew, M. H., Chong, P. C., Christensen, H. K., Clouston, H., Codd, M., Collins, D., Colquhoun, A. J., Corr, A., Coscia, M., Coyne, P. E., Creavin, B., Croner, R. S., Damjanovic, L., Daniels, I. R., Davies, M., Davies, R. J., Delaney, C. P., Denost, Q., Deutsch, C., Dietz, D., Domingo, S., Dozois, E. J., Duff, M., Eglinton, T., Enrique‐Navascues, J. M., Espin‐Basany, E., Evans, M. D., Fearnhead, N. S., Flatmark, K., Fleming, F., Frizelle, F. A., Gallego, M. A., Garcia‐Granero, E., Garcia‐Sabrido, J. L., Gentilini, L., George, M. L., Ghouti, L., Giner, F., Ginther, N., Glynn, R., Golda, T., Griffiths, B., Harris, D. A., Hagemans, J. A. W., Hanchanale, V., Harji, D. P., Helewa, R. M., Heriot, A. G., Hochman, D., Hohenberger, W., Holm, T., Hompes, R., Jenkins, J. T., Kaffenberger, S., Kandaswamy, G. V., Kapur, S., Kanemitsu, Y., Kelley, S. R., Keller, D. S., Khan, M. S., Kiran, R. P., Kim, H., Kim, H. J., Koh, C. E., Kok, N. F. M., Kokelaar, R., Kontovounisios, C., Kristensen, H. Ø., Kroon, H. M., Kusters, M., Lago, V., Larsen, S. G., Larson, D. W., Law, W. L., Laurberg, S., Lee, P. J., Limbert, M., Lydrup, M. L., Lyons, A., Lynch, A. C., Mantyh, C., Mathis, K. L., Margues, C. F. S., Martling, A., Meijerink, W. J. H. J., Merkel, S., Mehta, A. M., McArthur, D. R., McDermott, F. D., McGrath, J. S., Malde, S., Mirnezami, A., Monson, J. R. T., Morton, J. R., Mullaney, T. G., Negoi, I., Neto, J. W. M., Nguyen, B., Nielsen, M. B., Nieuwenhuijzen, G. A. P., Nilsson, P. J., O’Connell, P. R., O’Dwyer, S. T., Palmer, G., Pappou, E., Park, J., Patsouras, D., Pellino, G., Peterson, A. C., Poggioli, G., Proud, D., Quinn, M., Quyn, A., Radwan, R. W., van Ramshorst, G. H., Rasheed, S., Rasmussen, P. C., Regenbogen, S. E., Renehan, A., Rocha, R., Rochester, M., Rohila, J., Rothbarth, J., Rottoli, M., Roxburgh, C., Rutten, H. J. T., Ryan, É. J., Safar, B., Sagar, P. M., Sahai, A., Saklani, A., Sammour, T., Sayyed, R., Schizas, A. M. P., Schwarzkopf, E., Scripcariu, V., Selvasekar, C., Shaikh, I., Hellawell, G., Shida, D., Simpson, A., Smart, N. J., Smart, P., Smith, J. J., Solbakken, A. M., Solomon, M. J., Sørensen, M. M., Steele, S. R., Steffens, D., Stitzenberg, K., Stocchi, L., Stylianides, N. A., Sumrien, H., Sutton, P. A., Swartking, T., Taylor, C., Tekkis, P. P., Teras, J., Thurairaja, R., Toh, E. L., Tsarkov, P., Tsukada, Y., Tsukamoto, S., Tuech, J. J., Turner, W. H., Tuynman, J. B., Vasquez‐Jimenez, W., Verhoef, C., Vizzielli, G., Voogt, E. L. K., Uehara, K., Wakeman, C., Warrier, S., Wasmuth, H. H., Weber, K., Weiser, M. R., Wheeler, J. M. D., Wild, J., Wilson, M., de Wilt, J. H. W., Wolthuis, A., Yano, H., Yip, B., Yip, J., Yoo, R. N., van Zoggel, D., Winter, D. C.

Publikováno v: Colorectal Disease, 22(10), 1258-1262. Wiley-Blackwell
Colorectal Disease, 22, 10, pp. 1258-1262
Colorectal disease, 22(10), 1258-1262. Wiley-Blackwell
PelvEx Collaborative 2020, ' Simultaneous pelvic exenteration and liver resection for primary rectal cancer with synchronous liver metastases: results from the PelvEx Collaborative ', Colorectal Disease, vol. 22, no. 10, pp. 1258-1262 . https://doi.org/10.1111/codi.15064
Colorectal Disease, 22, 1258-1262

Aim: At presentation, 15–20% of patients with rectal cancer already have synchronous liver metastases. The aim of this study was to determine the surgical and survival outcomes in patients with advanced rectal cancer who underwent combined pelvic e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27bed751983fbf78cb0e98cf0ddf86f5
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85094684238&origin=inward

Pleomorphic liposarcoma with liver metastasis diagnosed by combined fine-needle aspiration cytology and core-needle biopsy

Autor: Valeria Ciliberti, Pasquale Cretella, Pio Zeppa, Alessandro Caputo

Publikováno v: Diagnostic cytopathology. 50(1)

Pleomorphic liposarcoma (PLPS) is the rarest liposarcoma subtype, with high-local recurrence and metastasis rates. Fine-needle aspiration cytology (FNAC) is successfully used in the diagnosis of primary or metastatic soft tissue tumors, but liver met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e67eea6a658da705df8a398d057603
https://pubmed.ncbi.nlm.nih.gov/34528402

Liver Resection for Neuroendocrine Tumor Liver Metastases Within Milan Criteria for Liver Transplantation

Autor: Giorgio Ercolani, Nadia Russolillo, Luca Aldrighetti, Guido Torzilli, Alfredo Guglielmi, Agostino Maria De Rose, Francesca Bertuzzo, Andrea Ruzzenente, Francesca Ratti, Alessandro Cucchetti, Simone Conci, Alessandro Ferrero, Pasquale Perri, Gian Luca Grazi, Matteo Cimino, Andrea Dore, Tommaso Campagnaro, Calogero Iacono, Fabio Bagante, Felice Giuliante

Publikováno v: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 23(1)

Background: The role of liver transplant (LT) for neuroendocrine liver metastasis (NELM) has not been completely defined. While international guidelines included LT as a potential treatment for highly selected patients with advanced NELM, recently, L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f504ea87e09c365c177988ec6557d8
https://pubmed.ncbi.nlm.nih.gov/30242647