Zobrazeno 1 - 10
of 67
pro vyhledávání: '"liquid profiling"'
Autor:
Gamisch Alexander, Mustafa Hans Georg, Haushofer Alexander, Mustafa-Korninger Maria-Elisabeth
Publikováno v:
Journal of Laboratory Medicine, Vol 48, Iss 4, Pp 141-151 (2024)
Liquid biopsy (LB) represents an advanced, minimally invasive approach that elevates the precision of oncological decision-making by identifying tumor DNA in bodily fluids. However, despite numerous endorsements from international specialty societies
Externí odkaz:
https://doaj.org/article/d4dd00f2a5224e6da7a68e0f69f85227
Autor:
Mack Matthias, Broche Julian, George Stephen, Hajjari Zahra, Janke Florian, Ranganathan Lavanya, Ashouri Mohammadreza, Bleul Sabine, Desuki Alexander, Engels Cecilia, Fliedner Stephanie M.J., Hartmann Nils, Hummel Michael, Janning Melanie, Kiel Alexander, Köhler Thomas, Koschade Sebastian, Lablans Martin, Lambarki Mohamed, Loges Sonja, Lueong Smiths, Meyer Sandra, Ossowski Stephan, Scherer Florian, Schroeder Christopher, Skowronek Patrick, Thiede Christian, Uhl Barbara, Vehreschild Jörg Janne, von Bubnoff Nikolas, Wagner Sebastian, Werner Tamara V., Westphalen C. Benedikt, Fresser Patrizia, Sültmann Holger, Tinhofer Ingeborg, Winter Christof
Publikováno v:
Journal of Laboratory Medicine, Vol 46, Iss 4, Pp 321-330 (2022)
Testing for genetic alterations in tumor tissue allows clinicians to identify patients who most likely will benefit from molecular targeted treatment. EXLIQUID – exploiting liquid biopsies to advance cancer precision medicine – investigates the p
Externí odkaz:
https://doaj.org/article/5ef881dedc404185a61e429fb791ee07
Publikováno v:
Journal of Laboratory Medicine, Vol 46, Iss 4, Pp 225-236 (2022)
Circulating tumor DNA (ctDNA), accurately described by the term liquid profiling (LP), enables real-time assessment of the tumor mutational profile as a minimally invasive test and has therefore rapidly gained traction, particular for the management
Externí odkaz:
https://doaj.org/article/665e5a2274dd483a96455565481b9136
Publikováno v:
Journal of Laboratory Medicine, Vol 46, Iss 4, Pp 247-253 (2022)
Early detection is crucial for optimal treatment and prognosis of cancer. New approaches for pan-cancer screening comprise the comprehensive characterization of circulating tumor DNA (ctDNA) in plasma by next generation sequencing and molecular profi
Externí odkaz:
https://doaj.org/article/8d665e2db8654ff1bc5b2e52ca4fdc8d
Publikováno v:
Journal of Laboratory Medicine, Vol 46, Iss 4, Pp 255-264 (2022)
The heterogeneity of each individual oncologic disease can be mirrored by molecular analysis of a simple blood draw in real time. Liquid biopsy testing has been shown useable for cancer detection, proof of minimal residual disease, therapy decision m
Externí odkaz:
https://doaj.org/article/fdb14286dc4f4650b7b7fb61f53d7fd7
Autor:
Maren Hedtke, Rodrigo Pessoa Rejas, Matthias F. Froelich, Volker Ast, Angelika Duda, Laura Mirbach, Victor Costina, Uwe M. Martens, Ralf‐Dieter Hofheinz, Michael Neumaier, Verena Haselmann
Publikováno v:
Molecular Oncology, Vol 16, Iss 10, Pp 2042-2056 (2022)
The analysis of circulating tumor DNA (ctDNA) is at the threshold of implementation into standard care for colorectal cancer (CRC) patients. However, data about the clinical utility of liquid profiling (LP), its acceptance by clinicians, and its inte
Externí odkaz:
https://doaj.org/article/c1e5149860064c5e8fd192d932a6be65
Publikováno v:
Journal of Laboratory Medicine, Vol 46, Iss 4, Pp 203-205 (2022)
Externí odkaz:
https://doaj.org/article/d408f6c4df914bcb864642dab67e0c52
Autor:
Michael Fleischhacker, Erkan Arslan, Dana Reinicke, Stefan Eisenmann, Gerit Theil, Jens Kollmeier, Christoph Schäper, Christian Grah, Frank Klawonn, Stefan Holdenrieder, Bernd Schmidt
Publikováno v:
Diagnostics, Vol 13, Iss 13, p 2131 (2023)
Notwithstanding some improvement in the earlier detection of patients with lung cancer, most of them still present with a late-stage disease at the time of diagnosis. Next to the most frequently utilized factors affecting the prognosis of lung cancer
Externí odkaz:
https://doaj.org/article/85592a9a4aae4159bd92bf23416a82df
Autor:
Fleischhacker Michael, Schmidt Bernd
Publikováno v:
Journal of Laboratory Medicine, Vol 44, Iss 3, Pp 117-142 (2020)
It is well documented that in the chain from sample to the result in a clinical laboratory, the pre-analytical phase is the weakest and most vulnerable link. This also holds for the use and analysis of extracellular nucleic acids. In this short revie
Externí odkaz:
https://doaj.org/article/52eca2f443214853b76caa4d749fa083
Autor:
Inga Medina Diaz, Annette Nocon, Stefanie A. E. Held, Makbule Kobilay, Dirk Skowasch, Abel J. Bronkhorst, Vida Ungerer, Johannes Fredebohm, Frank Diehl, Stefan Holdenrieder, Frank Holtrup
Publikováno v:
Diagnostics, Vol 13, Iss 7, p 1288 (2023)
Excellent pre-analytical stability is an essential precondition for reliable molecular profiling of circulating tumor DNA (ctDNA) in oncological diagnostics. Therefore, in vitro degradation of ctDNA and the additional release of contaminating genomic
Externí odkaz:
https://doaj.org/article/75a3dca641484427822aeb8e9a4e500f