Zobrazeno 1 - 10
of 1 752
pro vyhledávání: '"liquid biopsies."'
Autor:
Óscar Rapado-González, Sofia Salta, Rafael López-López, Rui Henrique, María Mercedes Suárez-Cunqueiro, Carmen Jerónimo
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract More than 50% of oral cancer (OC) patients are diagnosed with advanced-stage disease associated with poor prognosis and quality of life, supporting an urgent need to improve early OC detection. The identification of effective molecular marke
Externí odkaz:
https://doaj.org/article/ccaf5b4c07444139910e11a3cb77b077
Autor:
Hemerson Casado Gama, Mariana A. Amorós, Mykaella Andrade de Araújo, Congzhou M. Sha, Mirella P.S. Vieira, Rayssa G.D. Torres, Gabriela F. Souza, Janaína A. Junkes, Nikolay V. Dokholyan, Daniel Leite Góes Gitaí, Marcelo Duzzioni
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 2, Pp 523-535 (2024)
The discovery of disease-specific biomarkers, such as microRNAs (miRNAs), holds the potential to transform the landscape of Amyotrophic Lateral Sclerosis (ALS) by facilitating timely diagnosis, monitoring treatment response, and accelerating drug dis
Externí odkaz:
https://doaj.org/article/484ccf4e00ca48b0b33845585584869b
Autor:
Florian Tran, Alena Scharmacher, Nathan Baran, Neha Mishra, Marek Wozny, Samuel Pineda Chavez, Archana Bhardwaj, Sophia Hinz, Simonas Juzenas, Joana P. Bernardes, Laura Katharina Sievers, Matthias Lessing, Konrad Aden, Arne Lassen, Arne Bergfeld, Hauke Jann Weber, Lennart Neas, Stefania Vetrano, Stefan Schreiber, Philip Rosenstiel
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Blood-based biomarkers that reliably indicate disease activity in the intestinal tract are an important unmet need in the management of patients with IBD. Extracellular vesicles (EVs) are cell-derived membranous microparticles, which reflect
Externí odkaz:
https://doaj.org/article/8d4d477204f94e37b6475a01df6352d4
Autor:
Ji Young Lee, Byeong‐Ho Jeong, Ho Sang Jung, Taejoon Kang, Yeonkyung Park, Jin Kyung Rho, Sung‐Gyu Park, Min‐Young Lee
Publikováno v:
Small Science, Vol 4, Iss 8, Pp n/a-n/a (2024)
Economical mutation detection method with high analytical and clinical sensitivity is necessary for early cancer diagnosis and screening. In this study, a novel 3D‐nanoplasmonic‐based multiplex mutation assay chip is developed to detect epidermal
Externí odkaz:
https://doaj.org/article/3cfb357d2b944f829b82e7291ee6707e
Publikováno v:
Medicine in Omics, Vol 11, Iss , Pp 100039- (2024)
In the recent years, the development of so-called omics technologies has greatly contributed to the discovery of new biomarkers and targets, spanning different areas from diagnosis to therapy, and helping to accelerate the progress of precision and p
Externí odkaz:
https://doaj.org/article/aebfc8414ce9478abe18d3d5d60c1907
Autor:
Maksym A. Jopek, Krzysztof Pastuszak, Sebastian Cygert, Myron G. Best, Thomas Wurdinger, Jacek Jassem, Anna J. Zaczek, Anna Supernat
Publikováno v:
IEEE Journal of Translational Engineering in Health and Medicine, Vol 12, Pp 306-313 (2024)
The field of cancer diagnostics has been revolutionized by liquid biopsies, which offer a bridge between laboratory research and clinical settings. These tests are less invasive than traditional biopsies and more convenient than routine imaging metho
Externí odkaz:
https://doaj.org/article/f8bdbbadc6a4484d810ec5d2b00b4317
Autor:
Roberto Silvestri, Filomena Rea, Marianna Vitiello, Gabriele Moretti, Vittorio Aprile, Marco Lucchi, Paolo Aretini, Chiara Maria Mazzanti, Stefano Landi, Federica Gemignani
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32152- (2024)
Objectives: This study aims to determine whether the sequencing of DNA extracted from pleural fluids (PFs) of Pleural Mesothelioma (PM) patients accurately represents the genetic information obtained from the solid tissue counterpart biopsies with pa
Externí odkaz:
https://doaj.org/article/4e2a57cd4d2047b8b378ebb94f5af9b0
Autor:
Amir Razavinia, Abazar Razavinia, Roya Jamshidi Khalife Lou, Mahlegha Ghavami, Forouzan Shahri, Aida Tafazoli, Bahman Khalesi, Zahra Sadat Hashemi, Saeed Khalili
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32875- (2024)
Background: Renal Cell Carcinoma (RCC) stands as a formidable challenge within the field of oncology, despite considerable research endeavors. The advanced stages of this malignancy present formidable barriers to effective treatment and management. O
Externí odkaz:
https://doaj.org/article/306980634e3d494d812ea89975a2e1f2
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/bef89d4e33fe4ab2a107bc22c52c2fc4
Autor:
Luiz Fernando de Queiroz, Marcelo Soares da Mota e Silva, Heitor Siffert Pereira de Souza, Siane Lopes Bittencourt Rosas, Maria da Glória da Costa Carvalho
Publikováno v:
São Paulo Medical Journal, Vol 142, Iss 5 (2024)
ABSTRACT BACKGROUND: The human telomerase reverse transcriptase (hTERT) enzyme, encoded by the hTERT gene, synthesizes protective telomeric sequences on chromosomes and plays a fundamental role in cancer formation. Methylation of the hTERT gene has a
Externí odkaz:
https://doaj.org/article/a51bcdf46dc44813b600784b559b5928