Zobrazeno 1 - 10
of 163
pro vyhledávání: '"lipin-1"'
Publikováno v:
Endocrine and Metabolic Science, Vol 15, Iss , Pp 100165- (2024)
Introduction: Metabolic syndrome (MetS) is increasing healthcare costs worldwide. It has been suggested that serum lipin-1 (LPN1) may be associated with components of MetS. The aim of this study was to evaluate LPN1serum levels and its association wi
Externí odkaz:
https://doaj.org/article/e6584187a828449dadcbba25199e3420
Autor:
Negar Dinarvand, Reza Azizi, Sedighe Rastaghi, Farzaneh Karimi, Abdolkarim Sheikhi, Morteza Pourfarzam
Publikováno v:
Advanced Biomedical Research, Vol 13, Iss 1, Pp 83-83 (2024)
Background: Disturbances in lipid metabolism are one of the hallmarks of cancer cells. Fatty acid synthesis and oxidation play a crucial role in the proliferation, growth, and survival of cancer cells. Several enzymes are involved in lipid metabolism
Externí odkaz:
https://doaj.org/article/f38f9bfffbdc4417b0d636af7acb0742
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Sunitha Chandran, Robert M. Schilke, Cassidy M. R. Blackburn, Aila Yurochko, Rusella Mirza, Rona S. Scott, Brian N. Finck, Matthew D. Woolard
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Macrophage responses contribute to a diverse array of pathologies ranging from infectious disease to sterile inflammation. Polarization of macrophages determines their cellular function within biological processes. Lipin-1 is a phosphatidic acid phos
Externí odkaz:
https://doaj.org/article/2f929f1134fb4913933bcb98fe4f56da
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4419 (2021)
The rewiring of lipid metabolism is a major adaptation observed in cancer, and it is generally associated with the increased aggressiveness of cancer cells. Targeting lipid metabolism is therefore an appealing therapeutic strategy, but it requires a
Externí odkaz:
https://doaj.org/article/33d111488ff84aff9f68bc9f93e7f030
Autor:
Yanfei Qi, Tamar S. Kapterian, Ximing Du, Qianli Ma, Weihua Fei, Yuxi Zhang, Xun Huang, Ian W. Dawes, Hongyuan Yang
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 5, Pp 767-780 (2016)
The expansion of lipid droplets (LDs) and the differentiation of preadipocytes are two important aspects of mammalian lipid storage. In this study, we examined the role of CDP-diacylglycerol (DAG) synthases (CDSs), encoded by CDS1 and CDS2 genes in m
Externí odkaz:
https://doaj.org/article/65cdb491262c43e8b10cc19f3e4e759c
Autor:
I.A. Meijer, F. Sasarman, C. Maftei, E. Rossignol, M. Vanasse, P. Major, G.A. Mitchell, C. Brunel-Guitton
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 5, Iss C, Pp 85-88 (2015)
Fatty acid oxidation disorders and lipin-1 deficiency are the commonest genetic causes of rhabdomyolysis in children. We describe a lipin-1-deficient boy with recurrent, severe rhabdomyolytic episodes from the age of 4 years. Analysis of the LPIN1 ge
Externí odkaz:
https://doaj.org/article/d38e3cab9558483c83f9c714ccd30e72
Autor:
Ivana Elaković, Sanja Kovačević, Danijela Vojnović Milutinović, Aleksandra Nikolić-Kokić, Alhadi M. Glban, Mihajlo Spasić, Luc Tappy, Ana Djordjevic, Gordana Matić, Jelena Brkljačić
Publikováno v:
Nutrients, Vol 12, Iss 11, p 3470 (2020)
The effects of early-life fructose consumption on hepatic signaling pathways and their relation to the development of metabolic disorders in later life are not fully understood. To investigate whether fructose overconsumption at a young age induces a
Externí odkaz:
https://doaj.org/article/14189a3c8c7943bc96df14e2983616ef