Zobrazeno 1 - 10
of 192
pro vyhledávání: '"lipid lowering therapies"'
Autor:
Umberto Capece, Chiara Iacomini, Teresa Mezza, Alfredo Cesario, Carlotta Masciocchi, Stefano Patarnello, Andrea Giaccari, Nicoletta Di Giorgi
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Aims European registries and retrospective cohort studies have highlighted the failure to achieve low-density lipoprotein-cholesterol (LDL-C) targets in many very high-risk patients. Hospitalized patients are often frail, and frailty is asso
Externí odkaz:
https://doaj.org/article/679ea98b9a534d9996511bb7a846ffc2
Autor:
Michail I. Papafaklis, Rafail Koros, Grigorios Tsigkas, Antonios Karanasos, Athanasios Moulias, Periklis Davlouros
Publikováno v:
Biomedicines, Vol 12, Iss 11, p 2435 (2024)
Atherosclerotic plaque development constitutes the primary substrate of coronary artery disease (CAD) and is the outcome of an intricate process involving endothelial damage, inflammation, and lipid retention. The clinical efficacy of many lipid-lowe
Externí odkaz:
https://doaj.org/article/369cf1adce004adfaa79d92a54f2d604
Publikováno v:
Archives of Medical Science, Vol 19, Iss 6, Pp 1602-1615 (2023)
In 2023 there are still even 75% of patients over the target of low-density lipoprotein cholesterol (LDL-C), and hypercholesterolemia is the most common and the worst monitored cardiovascular risk factor. How it is possible, considering the knowledge
Externí odkaz:
https://doaj.org/article/5493de07a778401884bfb18583a2cbef
Publikováno v:
Pharmacological Research, Vol 200, Iss , Pp 107058- (2024)
Cardiovascular disease (CVD) remains the leading cause of death and disability worldwide. While many factors can contribute to CVD, atherosclerosis is the cardinal underlying pathology, and its development is associated with several metabolic risk fa
Externí odkaz:
https://doaj.org/article/0359eadbe934461280c5803f05d65696
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/a2a6719e749f4d588749915d3e6a43eb
Autor:
Yanzhen Zhang, Huaigang Chen, Lang Hong, Hong Wang, Bin Li, Mengyin Zhang, Jiamei Li, Liu Yang, Fan Liu
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Atherosclerotic heart disease (AHD) is a major cause of morbidity and mortality worldwide. Lowering low-density lipoprotein cholesterol (LDL-C) levels is a key strategy to prevent and treat AHD. Inclisiran is a novel siRNA drug that targets proprotei
Externí odkaz:
https://doaj.org/article/2ed9a00219ad4f05a7669eaa5eccf39c
Publikováno v:
Journal of Marine Medical Society, Vol 25, Iss 1, Pp 88-92 (2023)
Homozygous familial hypercholesterolemia (HoFH) is a rare, primarily an autosomal dominant genetic disorder that causes markedly elevated low-density lipoprotein (LDL) cholesterol levels predisposing patients to risk of developing premature atheroscl
Externí odkaz:
https://doaj.org/article/a21f53c57c2a43cbb77a3ab822db21fb
Autor:
Toshiyuki Nishikido
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-12 (2023)
Abstract Elevated low-density lipoprotein cholesterol (LDL-C) level is associated with an increased risk of atherosclerotic cardiovascular disease. Although high-intensity lipid-lowering therapies with statins and ezetimibe are highly effective for r
Externí odkaz:
https://doaj.org/article/8f873331588b430ea2843ef6d3f68b75
Autor:
Sajjad Chamani, Omid Kooshkaki, Maryam Moossavi, Mandana Rastegar, Sara Saffar Soflaei, Alice P. McCloskey, Maciej Banach, Amirhossein Sahebkar
Publikováno v:
Archives of Medical Science, Vol 19, Iss 5, Pp 1314-1326 (2022)
Statins are inhibitors of β-hydroxy β-methylglutaryl-CoA (HMG-CoA) reductase (HMGCR). They are used in patients with cardiovascular risk and/or suffering with cardiovascular disease. In addition to their efficient lipid-lowering effects, statins ex
Externí odkaz:
https://doaj.org/article/125a5cb6257745b487d5307dfbb1636a
Autor:
Petros Spyridonas Adamidis, Despoina Pantazi, Iraklis C. Moschonas, Evangelos Liberopoulos, Alexandros D. Tselepis
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 11, Iss 3, p 72 (2024)
Neutrophil extracellular traps (NETs) have attracted much attention recently, beyond elemental host immunity, due to their fundamental implication in a variety of pathologic conditions and widespread impactful diseases. Atherosclerotic cardiovascular
Externí odkaz:
https://doaj.org/article/64b33586f9a04b7e92075366706ed6b5