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Akademický článek

Review of the Patient Burden and Therapeutic Landscape of Irritable Bowel Syndrome with Constipation in the United States

Autor: Sendzischew Shane MA, Ruddy J, Cline M, Rosenbaum DP, Edelstein S, Moshiree B

Publikováno v: Clinical and Experimental Gastroenterology, Vol Volume 17, Pp 227-253 (2024)

Morgan Allyn Sendzischew Shane,1 Johannah Ruddy,2 Michael Cline,3 David P Rosenbaum,4 Susan Edelstein,4 Baharak Moshiree5 1Division of Gastroenterology and Digestive Disease, University of Miami, Miami, FL, USA; 2Patient Advocacy, Ardelyx, Inc., Walt

Externí odkaz: https://doaj.org/article/0fd4af68c0c04c07b0a473061312a117

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Akademický článek

Safety and efficacy of linaclotide combined with polyethylene glycol for bowel preparation

Autor: LI Xinlei, CHEN Xi, ZHANG Haiyan, JIANG Na, ZHANG Shan, CI Xiangnan, LIU Xishuang

Publikováno v: Jichu yixue yu linchuang, Vol 44, Iss 4, Pp 518-522 (2024)

Objective To evaluate safety and efficacy of linaclotide combined with polyethylene glycol(PEG) for bowel preparation. Methods A total of 612 patients from Department of Gastroenterology at the Affiliated Hospital of Qingdao University for colonoscop

Externí odkaz: https://doaj.org/article/fd6b6c0205514f9ea6a41e066112f3a1

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Akademický článek

Comparative profiles of lubiprostone, linaclotide, and elobixibat for chronic constipation: a systematic literature review with meta-analysis and number needed to treat/harm

Autor: Satish S. Rao, Noriaki Manabe, Yusuke Karasawa, Yuko Hasebe, Kazutaka Nozawa, Atsushi Nakajima, Shin Fukudo

Publikováno v: BMC Gastroenterology, Vol 24, Iss 1, Pp 1-19 (2024)

Abstract Objective To comprehensively evaluate the efficacy, safety, patient symptoms, and quality-of-life (QoL) of lubiprostone, linaclotide, and elobixibat as treatment for chronic constipation (CC). Design Systematic literature review (SLR) and me

Externí odkaz: https://doaj.org/article/df02ee8bb1ee4c928d0f1dddab4be884

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Akademický článek

The gut microbiota participates in the effect of linaclotide in patients with irritable bowel syndrome with constipation (IBS-C): a multicenter, prospective, pre-post study

Autor: Jianyun Zhou, Haoqi Wei, An Zhou, Xu Xiao, Xia Xie, Bo Tang, Hui Lin, Li Tang, Ruiping Meng, Xiaoying Yuan, Jing Zhang, Cheng Huang, Baobao Huang, Xiping Liao, Tingting Zhong, Suyu He, Sai Gu, Shiming Yang

Publikováno v: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)

Abstract Background Interindividual variation characterizes the relief experienced by constipation-predominant irritable bowel syndrome (IBS-C) patients following linaclotide treatment. Complex bidirectional interactions occur between the gut microbi

Externí odkaz: https://doaj.org/article/ef705cc1471d4f07bdde1a9821af2c01

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Akademický článek

Bowel preparation efficacy and safety of compound polyethylene glycol electrolyte powder combined with linaclotide for colonoscopy: A randomized controlled trial

Autor: Jing Yang, Qian Wei, Zhixiong Xiang, Dangyan Wu, Zhuoying Lin

Publikováno v: JGH Open, Vol 7, Iss 9, Pp 636-639 (2023)

Abstract Background and Aim Adequate bowel preparation is essential for colonoscopy, which is important for detecting colon polyps and preventing colorectal cancer. Linaclotide is approved for irritable bowel syndrome with predominant constipation (I

Externí odkaz: https://doaj.org/article/254b15786c2842a686c531f6a543745b

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