Zobrazeno 1 - 10
of 82
pro vyhledávání: '"light chain 3B"'
Publikováno v:
Journal of Human Reproductive Sciences, Vol 15, Iss 4, Pp 343-350 (2022)
Background: Follicle development takes place under the control of hormonal and environmental stimuli. It suggested that to improve in vitro fertilisation outcomes in poor responders increasing gonadotropin doses be used. Excessive gonadotropin leads
Externí odkaz:
https://doaj.org/article/e27dbb893fd0422d9a341b0c17a82fab
Autor:
Xuan Wang, Qi-Hui Shao, Hao Zhou, Jun-Lu Wu, Wen-Qiang Quan, Ping Ji, Yi-Wen Yao, Dong Li, Zu-Jun Sun
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Ginkgolide B (GKB) is a major active component of the extracts of Ginkgo biloba leaves, and it has been used as an anti-cancer agent. However, it is unknown whether GKB has the therapeutic effects on lung cancer. Here, we studied
Externí odkaz:
https://doaj.org/article/0b562bfdb6744fdd849ba00549f140c5
Publikováno v:
Biology Open, Vol 9, Iss 11 (2020)
Transforming growth factor beta (TGFβ) promotes tumorigenesis by suppressing immune surveillance and inducing epithelial to mesenchymal transition (EMT). TGFβ may augment tumorigenesis by activating autophagy, which protects cancer cells from chemo
Externí odkaz:
https://doaj.org/article/5743438a8461425db237f7adce564638
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 12, Pp 2191-2199 (2018)
Lithium promotes autophagy and has a neuroprotective effect on spinal cord injury (SCI); however, the underlying mechanisms remain unclear. Therefore, in this study, we investigated the effects of lithium and the autophagy inhibitor 3-methyladenine (
Externí odkaz:
https://doaj.org/article/976f9b0a6bee4d058bcb67dd03514725
Autor:
Wei Gao, Shu-rui Chen, Meng-yao Wu, Kai Gao, Yuan-long Li, Hong-yu Wang, Chen-yuan Li, Hong Li
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 5, Pp 823-828 (2016)
Methylprednisolone markedly reduces autophagy and apoptosis after secondary spinal cord injury. Here, we investigated whether pretreatment of cells with methylprednisolone would protect neuron-like cells from subsequent oxidative damage via suppressi
Externí odkaz:
https://doaj.org/article/b545e9de928b44e38d003a815a10d227
Autor:
Shuang Gao, Zhong-ming Zhang, Zhao-liang Shen, Kai Gao, Liang Chang, Yue Guo, Zhuo Li, Wei Wang, Ai-mei Wang
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 6, Pp 977-982 (2016)
Atorvastatin, a lipid-lowering medication, provides neuroprotective effects, although the precise mechanisms of action remain unclear. Our previous studies confirmed activated autophagy following spinal cord injury, which was conducive to recovery of
Externí odkaz:
https://doaj.org/article/dfdfc6ab8b9f4181b33441e95bf8f907
Akademický článek
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Autor:
Öfele, Sarah
Das klassische Hodgkin Lymphom (cHL) kann oft erfolgreich behandelt werden, die Radio- und Chemotherapie sind jedoch stark toxisch und haben viele Langzeitwirkungen. Eine Behandlungsmöglichkeit mit weniger Nebenwirkungen ist der DNA-Methyltransferas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f484dd000ef6afbbf293f9214c43ecf9
Akademický článek
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Autor:
Sebastian Mueller, Shijin Wang, Vanessa Rausch, Linna Yu, Johannes Mueller, Cheng Chen, Franco Fortunato
Publikováno v:
Redox Biology
Redox Biology, Vol 46, Iss, Pp 102081-(2021)
Redox Biology, Vol 46, Iss, Pp 102081-(2021)
Background Alcoholic liver disease (ALD) is the most common liver disease worldwide and its underlying molecular mechanisms are still poorly understood. Moreover, conflicting data have been reported on potentially protective autophagy, the exact role