Zobrazeno 1 - 10
of 836
pro vyhledávání: '"ligand/receptor interaction"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Ligand-receptor interaction (LRI) prediction has great significance in biological and medical research and facilitates to infer and analyze cell-to-cell communication. However, wet experiments for new LRI discovery are costly and time-consum
Externí odkaz:
https://doaj.org/article/be524fca82ee421fa3a0494b301f1685
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Metabolite-associated cell communications play critical roles in maintaining human biological function. However, most existing tools and resources focus only on ligand-receptor interaction pairs where both partners are proteinaceo
Externí odkaz:
https://doaj.org/article/238994059a9c404e8d39cfee072cfa0d
Autor:
Yancheng Lai, Xiaole Lu, Yankai Liao, Pei Ouyang, Hai Wang, Xian Zhang, Guanglong Huang, Songtao Qi, Yaomin Li
Publikováno v:
Genes and Diseases, Vol 11, Iss 2, Pp 874-889 (2024)
Glioblastoma (GBM) is the most common intrinsic and aggressive primary brain tumor in adults, with a median survival of approximately 15 months. GBM heterogeneity is considered responsible for the treatment resistance and unfavorable prognosis. Prone
Externí odkaz:
https://doaj.org/article/6c4a8cd8dd684b6c96fc58b3b5060b77
Autor:
Atefeh Lafzi, Costanza Borrelli, Simona Baghai Sain, Karsten Bach, Jonas A Kretz, Kristina Handler, Daniel Regan-Komito, Xenia Ficht, Andreas Frei, Andreas Moor
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 2, Pp 98-119 (2024)
Abstract Sequencing-based spatial transcriptomics (ST) methods allow unbiased capturing of RNA molecules at barcoded spots, charting the distribution and localization of cell types and transcripts across a tissue. While the coarse resolution of these
Externí odkaz:
https://doaj.org/article/1622b8f5debc4d0a97fb157237705827
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionLeishmaniasis comprises a complex group of diseases caused by protozoan parasites from the Leishmania genus, presenting a significant threat to human health. Infection starts by the release into the skin of metacyclic promastigote (MP) fo
Externí odkaz:
https://doaj.org/article/78acb6cea7c8431aa3719f91dcfa4eb7
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
BackgroundThe heterogeneity of the tumor microenvironment significantly influences the prognosis of hepatocellular carcinoma (HCC) patients, with cell communication through ligand-receptor complexes playing a central role.MethodsWe conducted single-c
Externí odkaz:
https://doaj.org/article/bd4d407cbf4c4f6ea4653d5073d7efac
Autor:
Brianna J. McIntosh, Griffin G. Hartmann, Sean A. Yamada‐Hunter, Phillip Liu, Camille F. Williams, Julien Sage, Jennifer R. Cochran
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 6, Pp n/a-n/a (2023)
Abstract The cytokine interleukin (IL)‐11 has been shown to play a role in promoting fibrosis and cancer, including lung adenocarcinoma, garnering interest as an attractive target for therapeutic intervention. We used combinatorial methods to engin
Externí odkaz:
https://doaj.org/article/e074518fcf654bf4858ad1a87a84c9f0
Autor:
Parul Singh, Syed Azmal Ali
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 8, Iss , Pp 100106- (2023)
S100 proteins have emerged as key regulators in the mammary gland and have been implicated in breast cancer development and metastasis. This review provides a comprehensive overview of the roles of S100 proteins in mammary gland regulation and their
Externí odkaz:
https://doaj.org/article/a9617f6f9c214d54bb713a268c4ba09a
Publikováno v:
Vaccines, Vol 12, Iss 5, p 484 (2024)
The WHO reported an estimated 249 million malaria cases and 608,000 malaria deaths in 85 countries in 2022. A total of 94% of malaria deaths occurred in Africa, 80% of which were children under 5. In other words, one child dies every minute from mala
Externí odkaz:
https://doaj.org/article/e846ae60d3d2495e8b68fcc7fa809085
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.