Biodegradable polymer nanocomposites for ligament/tendon tissue engineering

Autor: Magda Silva, Fernando N. Ferreira, Natália M. Alves, Maria C. Paiva

Publikováno v: Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-33 (2020)

Abstract Ligaments and tendons are fibrous tissues with poor vascularity and limited regeneration capacity. Currently, a ligament/tendon injury often require a surgical procedure using auto- or allografts that present some limitations. These inadequa

Externí odkaz: https://doaj.org/article/3a795a241e4e41a19c65be64fdbdfda5

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Cruciate Ligament Cell Sheets Can Be Rapidly Produced on Thermoresponsive poly(glycidyl ether) Coating and Successfully Used for Colonization of Embroidered Scaffolds

Autor: Ingrid Zahn, Daniel David Stöbener, Marie Weinhart, Clemens Gögele, Annette Breier, Judith Hahn, Michaela Schröpfer, Michael Meyer, Gundula Schulze-Tanzil

Publikováno v: Cells, Vol 10, Iss 4, p 877 (2021)

Anterior cruciate ligament (ACL) cell sheets combined with biomechanically competent scaffolds might facilitate ACL tissue engineering. Since thermoresponsive polymers allow a rapid enzyme-free detachment of cell sheets, we evaluated the applicabilit

Externí odkaz: https://doaj.org/article/f47c66e240954449ac38e5f6409be117

Maintenance of Ligament Homeostasis of Spheroid-Colonized Embroidered and Functionalized Scaffolds after 3D Stretch

Autor: Judith A. Hahn, Michael T. Meyer, Bernd Hoffmann, Rudolf Merkel, Jens Konrad, Clemens Gögele, Annette Breier, Michaela Schröpfer, Gundula Schulze-Tanzil

Publikováno v: International Journal of Molecular Sciences
International journal of molecular sciences 22(15), 8204-(2021). doi:10.3390/ijms22158204
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 8204, p 8204 (2021)

Anterior cruciate ligament (ACL) ruptures are usually treated with autograft implantation to prevent knee instability. Tissue engineered ACL reconstruction is becoming promising to circumvent autograft limitations. The aim was to evaluate the influen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae3b4f1153697b21028003e55a334f8
http://europepmc.org/articles/PMC8348491

Enhanced Growth of Lapine Anterior Cruciate Ligament-Derived Fibroblasts on Scaffolds Embroidered from Poly(l-lactide-co-ε-caprolactone) and Polylactic Acid Threads Functionalized by Fluorination and Hexamethylene Diisocyanate Cross-Linked Collagen Foams

Autor: Clemens Gögele, Judith Hahn, Cindy Elschner, Annette Breier, Michaela Schröpfer, Ina Prade, Michael Meyer, Gundula Schulze-Tanzil

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 3, p 1132 (2020)

Reconstruction of ruptured anterior cruciate ligaments (ACLs) is limited by the availability and donor site morbidity of autografts. Hence, a tissue engineered graft could present an alternative in the future. This study was undertaken to determine t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::60ec2b60b941188d18ba3ec39387747f
https://www.mdpi.com/1422-0067/21/3/1132