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Diff4VS: HIV-inhibiting Molecules Generation with Classifier Guidance Diffusion for Virtual Screening

Autor: Lyu, Jiaqing, Chen, Changjie, Liang, Bing, Zhang, Yijia

The AIDS epidemic has killed 40 million people and caused serious global problems. The identification of new HIV-inhibiting molecules is of great importance for combating the AIDS epidemic. Here, the Classifier Guidance Diffusion model and ligand-bas

Externí odkaz: http://arxiv.org/abs/2407.15880

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A Comprehensive Evaluation on Event Reasoning of Large Language Models

Autor: Tao, Zhengwei, Jin, Zhi, Zhang, Yifan, Chen, Xiancai, Zhao, Haiyan, Li, Jia, Liang, Bing, Tao, Chongyang, Liu, Qun, Wong, Kam-Fai

Event reasoning is a fundamental ability that underlies many applications. It requires event schema knowledge to perform global reasoning and needs to deal with the diversity of the inter-event relations and the reasoning paradigms. How well LLMs acc

Externí odkaz: http://arxiv.org/abs/2404.17513

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Akademický článek

Liuwei Dihuang pills attenuate ovariectomy-induced bone loss by alleviating bone marrow mesenchymal stem cell (BMSC) senescence via the Yes-associated protein (YAP)-autophagy axis.

Autor: Liang, Bing¹ (AUTHOR), Chen, Xiongbin¹ (AUTHOR), Li, Min¹ (AUTHOR), Zhang, Lingling¹ (AUTHOR), Yang, Xia¹ (AUTHOR), Shi, Liangqin¹ (AUTHOR), Gong, Yanju¹ (AUTHOR), Gong, Yuanyuan¹ (AUTHOR), Xu, Huan¹ (AUTHOR), Wu, Xiao¹ (AUTHOR), Jin, Zhong¹ (AUTHOR), Wang, Yanru¹ (AUTHOR), Liu, Luwei¹ (AUTHOR), Yi, Xiaohong¹ (AUTHOR), Xie, Lushuang¹ (AUTHOR), Zhong, Hua¹ (AUTHOR), Shen, Chongyang¹ (AUTHOR), Wang, Yong¹ (AUTHOR), Yang, Lan¹ (AUTHOR) yanglan@cdutcm.edu.cn

Publikováno v: Pharmaceutical Biology. Dec2024, Vol. 62 Issue 1, p42-52. 11p.

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Akademický článek

缺血性视网膜损伤致细胞凋亡的内质网应激机制研究 Research on the Endoplasmic Reticulum Stress Mechanism of Apoptosis Induced by Ischemic Retinal Injury

Autor: 于文瑄，梁冰，曹永亮(YU Wenxuan, LIANG Bing, CAO Yongliang )

Publikováno v: Zhongguo cuzhong zazhi, Vol 19, Iss 6, Pp 664-671 (2024)

目的分析缺血对视网膜神经节细胞（retinal ganglion cells，RGCs）凋亡过程中内质网应激（endoplasmic reticulum stress，ERS）相关蛋白葡萄糖调节蛋白78（glucose regulated protein78，GRP78）、增强子结合蛋�

Externí odkaz: https://doaj.org/article/98790b747dac49ca9ad5121bf179cf59

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Reduced-order variational mode decomposition

Autor: Liao, Zi-Mo, Zhao, Zhiye, Chen, Liang-Bing, Wan, Zhen-Hua, Liu, Nan-Sheng, Lu, Xi-Yun

A novel data-driven method of modal analysis for complex flow dynamics, termed as reduced-order variational mode decomposition (RVMD), has been proposed, combining the idea of the separation of variables and a state-of-the-art nonstationary signal-pr

Externí odkaz: http://arxiv.org/abs/2209.12437

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