Zobrazeno 1 - 10
of 11
pro vyhledávání: '"li（范莉） Fan"'
Autor:
li（范莉） Fan, Yanqing Qin, Jiye Fang, Ruifen Zhang, Xia Li, Yuhai Chen, Haicheng Zhang, Yi Liu, Yonghua Xu, Min Li
Publikováno v:
Oncogene. 36:6738-6746
The endoplasmic reticulum (ER) stress occurs frequently in cancers. The unfolded protein response (UPR) is activated to cope with ER stress. This has generated widespread interest in targeting UPR as therapeutic strategies. Inositol-requiring transme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234ad7755614c0cff41e55aaf3c93135
https://doi.org/10.1038/onc.2017.284
https://doi.org/10.1038/onc.2017.284
Autor:
Yi-Ming Xu, Ying Chen, Guo-Hua Fong, Tang-Long Yuan, Hai-Sheng Zhang, Guohao Wu, Heng Sun, Jing（方靖） Fang, Chen-Guang Bai, Qiulei Xi, Yan-Qing Qin, li（范莉） Fan, Zhi-Qiang Ling
Publikováno v:
Journal of Biological Chemistry. 290:20580-20589
Prolyl hydroxylase domain proteins (PHDs) control cellular adaptation to hypoxia. PHDs are found involved in inflammatory bowel disease (IBD); however, the exact role of PHD3, a member of the PHD family, in IBD remains unknown. We show here that PHD3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc8f8014fa44320592a207460ab191f
https://doi.org/10.1074/jbc.m115.653584
https://doi.org/10.1074/jbc.m115.653584
Autor:
Hai-Sheng Zhang, Yun-Fang Zhang, Xuebing Li, Bing Yan, li（范莉） Fan, Jing（方靖） Fang, Guohao Wu, Min Li
Publikováno v:
Journal of Biological Chemistry. 287:44164-44172
Paired box (PAX) 2, a transcription factor, plays a critical role in embryogenesis. When aberrantly expressed in adult tissues, it generally exhibits oncogenic properties. However, the underlying mechanisms remain unclear. We reported previously that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938b3cbd383db93225cfb1f42be125f2
https://doi.org/10.1074/jbc.m112.401521
https://doi.org/10.1074/jbc.m112.401521
Publikováno v:
Journal of Biological Chemistry. 287:17737-17745
FOXO3a, a member of the Forkhead box O (FoxO) transcription factor family, is believed to be a tumor suppressor because it was found that FOXO3a inactivation promoted cell transformation and tumor progression. There are also a few studies showing tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8447048a327196dd75b189638d0d0b13
https://doi.org/10.1074/jbc.m111.291708
https://doi.org/10.1074/jbc.m111.291708
Autor:
Jing Xue, Guohao Wu, Dandan Lv, Jing（方靖） Fang, Shi Jiao, Bing Yan, li（范莉） Fan, Hai-Sheng Zhang
Publikováno v:
Biochemical and Biophysical Research Communications. 409:315-320
Prolyl hydroxylase domain proteins (PHDs) hydroxylate HIFα in the presence of oxygen, leading to HIFα proteasomal destruction. The PHDs family comprises PHD1, 2, and 3. Recent studies indicate that, in addition to HIFα, PHDs have other substrates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283a1435dbe21e200f6e12778b157ce7
https://doi.org/10.1016/j.bbrc.2011.05.012
https://doi.org/10.1016/j.bbrc.2011.05.012
Publikováno v:
The international journal of biochemistrycell biology. 53
TNF receptor associated factor 6 (TRAF6) plays a critical role in the regulation of innate immune responses and adaptive immune responses. Though recent studies indicate that TRAF6 is involved in cancer, its precise role in cancer including colon can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0e96311715cd05d1a0a31b877076f4
https://pubmed.ncbi.nlm.nih.gov/24755241
https://pubmed.ncbi.nlm.nih.gov/24755241
Publikováno v:
Cancer research. 73(15)
TNF receptor (TNFR)–associated factor TRAF6 is a key activator of NF-κB, playing a critical role in the regulation of innate immune responses and their connection to adaptive immune responses. TRAF6 interactions determine receptor-induced cell dea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5c4e39fb69d9577bf24b1b083705ca
https://pubmed.ncbi.nlm.nih.gov/23722539
https://pubmed.ncbi.nlm.nih.gov/23722539
Autor:
Yun-Fang Zhang, li（范莉） Fan, Wenting Zhao, Cheng-Fu Zhou, Jerry Pelletier, Jing（方靖） Fang, Xuebing Li
Publikováno v:
The Journal of biological chemistry. 288(23)
pVHL, the product of von Hippel-Lindau (VHL) tumor suppressor gene, functions as the substrate recognition component of an E3-ubiquitin ligase complex that targets hypoxia inducible factor α (HIF-α) for ubiquitination and degradation. Besides HIF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79794731ca188ade5b076cb7c239fe77
https://pubmed.ncbi.nlm.nih.gov/23612971
https://pubmed.ncbi.nlm.nih.gov/23612971
Autor:
Shi Jiao, Wenting Zhao, Guohao Wu, Xue-bing Li, Jing（方靖） Fang, Jing Xue, Heng Sun, li（范莉） Fan
Publikováno v:
Cancer letters. 309(2)
EAR2 is a member of the chick ovalbumin upstream promoter-transcription factors (COUP-TFs). COUP-TFs belong to orphan nuclear receptors and regulate many biological processes. Little is known regarding EAR2 in cancer, though much progress has been ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5463a1d107250591fb010bb585333c53
https://pubmed.ncbi.nlm.nih.gov/21696885
https://pubmed.ncbi.nlm.nih.gov/21696885
Publikováno v:
IUBMB life. 63(1)
Activating transcription factor 3 (ATF3) is a member of the ATF/CREB (CAMP responsive element binding protein) family of transcription factors. The expression and the function of ATF3 in vascular smooth muscle cells (VSMCs) remain unknown. The aim of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8446a3d759fb9aa1eaf6b2f5ae447ddd
https://pubmed.ncbi.nlm.nih.gov/21280179
https://pubmed.ncbi.nlm.nih.gov/21280179