Zobrazeno 1 - 10
of 599
pro vyhledávání: '"leukemic stem cell"'
Autor:
Nicole S Arellano, Shannon E Elf
Publikováno v:
eLife, Vol 13 (2024)
A new approach helps examine the proportion of cancerous and healthy stem cells in patients with chronic myeloid leukemia and how this influences treatment outcomes.
Externí odkaz:
https://doaj.org/article/4f5a9e5111414f65b282cdebbee7af40
Autor:
Rebecca Warfvinge, Linda Geironson Ulfsson, Parashar Dhapola, Fatemeh Safi, Mikael Sommarin, Shamit Soneji, Henrik Hjorth-Hansen, Satu Mustjoki, Johan Richter, Ram Krishna Thakur, Göran Karlsson
Publikováno v:
eLife, Vol 12 (2024)
The advent of tyrosine kinase inhibitors (TKIs) as treatment of chronic myeloid leukemia (CML) is a paradigm in molecularly targeted cancer therapy. Nonetheless, TKI-insensitive leukemia stem cells (LSCs) persist in most patients even after years of
Externí odkaz:
https://doaj.org/article/d2afc990e3264278aae9d3f9ec4607bc
Autor:
Santos de Macedo, Brunno Gilberto a, Albuquerque de Melo, Manuela a, Pereira-Martins, Diego Antonio b, Machado-Neto, João Agostinho a, c, Traina, Fabiola a, ⁎
Publikováno v:
In BBA - Reviews on Cancer November 2024 1879(6)
Autor:
Kobrossy, Laila 1, Xu, Weiyi 2, Zhang, Chunling 3, Feng, Wenyi 1, Turner, Christopher E. 2, Cosgrove, Michael S. 1, ∗
Publikováno v:
In Journal of Biological Chemistry November 2024 300(11)
Publikováno v:
In Trends in Pharmacological Sciences October 2024 45(10):919-930
Autor:
Kou, Ruirui a, Li, Tian b, Fu, Caizhu a, Jiang, Duanfeng a, Wang, Yue c, Meng, Jie a, Zhong, Ruilan a, Liang, Changjiu a, Dong, Min a, ∗
Publikováno v:
In Environmental Research 1 March 2024 244
Autor:
Jirarat Poohadsuan, George A. O’Doherty, Weerapat Owattanapanich, Smith Kungwankiattichai, Yon Rojanasakul, Surapol Issaragrisil, Sudjit Luanpitpong
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-23 (2023)
Abstract Background Acute myeloid leukemia (AML) is an aggressive hematologic malignancy characterized by an accumulation of immature leukemic myeloblasts initiating from leukemic stem cells (LSCs)—the subpopulation that is also considered the root
Externí odkaz:
https://doaj.org/article/cc661f683d5049babb9e6d7accbe4dd0
Autor:
Dong-Jin Han, Sunmin Kim, Seo-Young Lee, Su Jung Kang, Youngbeen Moon, Hoon Seok Kim, Myungshin Kim, Tae-Min Kim
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Background: Previous studies have reported that genes highly expressed in leukemic stem cells (LSC) may dictate the survival probability of patients and expression-based cellular deconvolution may be informative in forecasting prognosis. However, whe
Externí odkaz:
https://doaj.org/article/f9d97faac61a4e64804aa6176d94d2a4
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 3, Pp 2121-2135 (2023)
Mesenchymal stromal cells (MSC) are part of the bone marrow architecture and contribute to the homeostasis of hematopoietic stem cells. Moreover, they are known to regulate immune effector cells. These properties of MSC are pivotal under physiologic
Externí odkaz:
https://doaj.org/article/a400e6fc914e4570978c5910f8d0ca25
Autor:
Wang, Chen 1, 7, Nistala, Ravi 1, 2, 7, Cao, Min 1, Pan, Yi 1, Behrens, Madelaine 1, Doll, Donald 3, Hammer, Richard D. 4, Nistala, Puja 3, Chang, Hui-Ming 5, 6, Yeh, Edward T.H. 6, Kang, XunLei 1, 3, 8, ∗
Publikováno v:
In Cell Reports 28 February 2023 42(2)