Zobrazeno 1 - 10
of 1 520
pro vyhledávání: '"leptomeningeal metastasis"'
Autor:
Yutaka Fujiwara, Katsuhiro Masago, Reiko Matsuzawa, Teppei Yamaguchi, Naohiro Watanabe, Junichi Shimizu, Eiichi Sasaki, Yoshitsugu Horio
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 942-949 (2024)
Introduction: Patients with anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer (NSCLC) are at increased risk of central nervous system (CNS) metastasis at initial diagnosis and throughout treatment. In a phase 3 trial, lorlatinib,
Externí odkaz:
https://doaj.org/article/2aba73a40393419a80bec87fda815105
Publikováno v:
Zhongguo aizheng zazhi, Vol 34, Iss 7, Pp 695-701 (2024)
Leptomeningeal metastasis (LM) is a serious late complication in patients with solid tumors, which is common in patients with lung cancer, breast cancer and melanoma. In recent years, due to the progress of diagnosis, the diagnosis rate of LM has gra
Externí odkaz:
https://doaj.org/article/cd3e98ad6d3c446d96ff639de09a9ee3
Autor:
Elena Pentsova
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
A common feature of advanced solid tumors is their ability to metastasize and colonize distant organs, including the Central Nervous System (CNS), which encompasses brain and leptomeningeal metastases (LM). While cerebrospinal fluid cytopathological
Externí odkaz:
https://doaj.org/article/1b4a3882b6c0490ba789c4826d925064
Autor:
Yubin LI, Xiaoyan LI
Publikováno v:
Chinese Journal of Lung Cancer, Vol 27, Iss 5, Pp 376-382 (2024)
Leptomeningeal metastasis (LM) is a lethal complication of malignant tumors, with an incidence rate of 3%-5% among patients with non-small cell lung cancer (NSCLC). LM poses significant challenges in diagnosis, has poor prognosis, limited treatment o
Externí odkaz:
https://doaj.org/article/84b9bf3b4b9e47bb91925ef0b0071877
Publikováno v:
Zhongguo aizheng zazhi, Vol 34, Iss 4, Pp 389-399 (2024)
Background and purpose: Leptomeningeal metastasis is a form of central nervous system metastasis of melanoma. High mobility group A2 (HMGA2) has been proven to play an important role in the occurrence and development of various tumors, but its biolog
Externí odkaz:
https://doaj.org/article/3262d8b16dc043d3a78dbc1bf4c5f37f
Publikováno v:
Drug Delivery, Vol 31, Iss 1 (2024)
Leptomeningeal disease (LMD) refers to the infiltration of cancer cells into the leptomeningeal compartment. Leptomeninges are the two membranous layers, called the arachnoid membrane and pia mater. The diffuse nature of LMD poses a challenge to its
Externí odkaz:
https://doaj.org/article/ace05960f5e4499f8f88ef50f5828ede
Autor:
Matan Ben-Zion Berliner, Shlomit Yust-Katz, Inbar Lavie, Yael Goldberg, Inbal Kedar, Rinat Yerushalmi
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Breast cancer is a common cause for central nervous system (CNS) metastasis, resulting in a significant reduction in overall survival. Germline pathogenic variants (PVs) in BRCA1/2 are the most common genetic risk factor for breas
Externí odkaz:
https://doaj.org/article/506d52925bef46a19f0d9778497c654c
Autor:
Hiromune Sawada, Yuri Taniguchi, Shin Iizuka, Toshiki Ikeda, Masaharu Aga, Yusuke Hamakawa, Kazuhito Miyazaki, Yuki Misumi, Yoko Agemi, Yukiko Nakamura, Koki Maeda, Tsuneo Shimokawa, Hiroaki Okamoto
Publikováno v:
Case Reports in Oncology, Vol 16, Iss 1, Pp 1558-1567 (2023)
Introduction: C-ros oncogene 1 (ROS1) translocation is an oncogenic driver-mutation identified in 1–2% of non-small-cell lung cancer (NSCLC) cases. Although crizotinib, a tyrosine kinase inhibitor (TKI) against ALK/ROS1, is known to be effective ag
Externí odkaz:
https://doaj.org/article/97ef3a05d08549e587029f538dbb0f84
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Leptomeningeal metastasis (LM) is a complication of non-small cell lung cancer (NSCLC) characterized by poor prognosis and short survival. A variety of therapeutic approaches have been sought to improve the efficacy of LM. Here we present a clinical
Externí odkaz:
https://doaj.org/article/afd8fa2bb2ea40828ebfcdda154456cb
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/7e630d635eb24034a6c1e709d800408b