Zobrazeno 1 - 10
of 1 223
pro vyhledávání: '"leptin deficiency"'
Autor:
Beatriz de Luxán-Delgado, Yaiza Potes, Adrian Rubio-González, Juan José Solano, José Antonio Boga, Eduardo Antuña, Cristina Cachán-Vega, Juan Carlos Bermejo-Millo, Nerea Menéndez-Coto, Claudia García-González, Gonçalo C. Pereira, Beatriz Caballero, Ana Coto-Montes, Ignacio Vega-Naredo
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8677 (2024)
Despite efforts to elucidate the cellular adaptations induced by obesity, cellular bioenergetics is currently considered a crucial target. New strategies to delay the onset of the hazardous adaptations induced by obesity are needed. Therefore, we eva
Externí odkaz:
https://doaj.org/article/d66aee3f9e3045d2b89ca692aed2ab84
Akademický článek
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Autor:
Francesco Suriano, Sara Vieira-Silva, Gwen Falony, Martin Roumain, Adrien Paquot, Rudy Pelicaen, Marion Régnier, Nathalie M. Delzenne, Jeroen Raes, Giulio G. Muccioli, Matthias Van Hul, Patrice D. Cani
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-20 (2021)
Abstract Background Leptin-deficient ob/ob mice and leptin receptor-deficient db/db mice are commonly used mice models mimicking the conditions of obesity and type 2 diabetes development. However, although ob/ob and db/db mice are similarly gaining w
Externí odkaz:
https://doaj.org/article/d890b4d856184f9f98fdd2efbb56f9bd
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundWhile for individuals with obesity an association between hyperleptinemia and an increased risk of non-alcoholic fatty liver disease (NAFLD) is assumed, a leptin deficiency is also related to the development of NAFLD early in life in ob/ob
Externí odkaz:
https://doaj.org/article/8138b53b302e4b848ccc71c7015b5c9d
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 14, Pp 3325-3336 (2020)
Rong-zi Li,1 Xiao-Wen Ding,1 Thangiah Geetha,1 Layla Al-Nakkash,2 Tom L Broderick,2 Jeganathan Ramesh Babu1 1Department of Nutrition, Dietetics and Hospitality Management, Auburn University, Auburn, AL 36849, USA; 2Department of Physiology, Laborator
Externí odkaz:
https://doaj.org/article/4001f16ec4ce4c06aa51af58d1261090
Autor:
Daniela Boschetti, Cynthia R. Muller, Anna Laura V. Américo, Bruno Vecchiatto, Luiz Felipe Martucci, Renata O. Pereira, Cláudia P. Oliveira, Patricia Fiorino, Fabiana S. Evangelista, Anna Karenina Azevedo-Martins
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Obesity is associated with increased risk of several chronic diseases and the loss of disease-free years, which has increased the focus of much research for the discovery of therapy to combat it. Under healthy conditions, women tend to store more fat
Externí odkaz:
https://doaj.org/article/bb5ad15327a94305a1264de0aec103b6
Akademický článek
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Autor:
Kaio Cezar Rodrigues Salum, Jônatas de Mendonça Rolando, Verônica Marques Zembrzuski, João Regis Ivar Carneiro, Cicero Brasileiro Mello, Clarissa Menezes Maya-Monteiro, Patrícia Torres Bozza, Fabiana Barzotto Kohlrausch, Ana Carolina Proença da Fonseca
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Obesity is a pandemic condition of complex etiology, resulting from the increasing exposition to obesogenic environmental factors combined with genetic susceptibility. In the past two decades, advances in genetic research identified variants of the l
Externí odkaz:
https://doaj.org/article/77daf4417fc24b3fa4a63d4b9b4b79b5
Autor:
Alireza Kashani, Asker Daniel Brejnrod, Chunyu Jin, Timo Kern, Andreas Nygaard Madsen, Louise Aas Holm, Georg K. Gerber, Jens-Christian Holm, Torben Hansen, Birgitte Holst, Manimozhiyan Arumugam
Publikováno v:
Animal Microbiome, Vol 1, Iss 1, Pp 1-16 (2019)
Abstract Background Growing evidence supports the role of gut microbiota in obesity and its related disorders including type 2 diabetes. Ob/ob mice, which are hyperphagic due to leptin deficiency, are commonly used models of obesity and were instrume
Externí odkaz:
https://doaj.org/article/0385eceaef9b422d9130571692ef5b3d
Akademický článek
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