Zobrazeno 1 - 10
of 1 239
pro vyhledávání: '"leishmanicidal"'
Autor:
LILYANA WALESKA N. ALBUQUERQUE, SHAKIRA C.A. FERREIRA, IZABELLY CAROLLYNNY M. NUNES, HILDA CAROLINE N. SANTOS, MARIANA S. SANTOS, MÁRCIO THOMAZ S. VARJÃO, AMANDA EVELYN DA SILVA, ANDERSON B. LEITE, ALYSSON W.F. DUARTE, MAGNA SUZANA ALEXANDRE-MOREIRA, ALINE C. DE QUEIROZ
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 96, Iss 3 (2024)
Abstract Leishmaniasis is a disease of public health relevance that demands new therapeutic alternatives due to the toxicity of conventional treatments. In this study, 27 plants of interest to the Unified Health System (SUS) were evaluated for cytoto
Externí odkaz:
https://doaj.org/article/4910a4f154f14a32990345876465d524
Autor:
Maria Carolina Silva Marques, Nídia Cristiane Yoshida, Eduardo Caio Torres-Santos, Fernanda Rodrigues Garcez, Walmir Silva Garcez
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionLeishmaniasis, a neglected tropical parasitic disease, is regarded as a major public health problem worldwide. The first-line drugs for leishmaniasis suffer from limitations related to toxicity and the development of resistance in certain
Externí odkaz:
https://doaj.org/article/b75e1efb896c40ca89003bccab506aaa
Autor:
ROSANE D. CEZAR, ADRIANO O. DA SILVA, ROSÂNGELA S. LOPES, CELSO V. NAKAMURA, JEAN HENRIQUE S. RODRIGUES, ESTELA MARIANA G. LOURENÇO, SUMBAL SABA, ADILSON BEATRIZ, JAMAL RAFIQUE, DÊNIS P. DE LIMA
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 96, Iss 2 (2024)
Abstract In pursuit of potential agents to treat Chagas disease and leishmaniasis, we report the design, synthesis, and identification novel naphthoquinone hydrazide-based molecular hybrids. The compounds were subjected to in vitro trypanocide and le
Externí odkaz:
https://doaj.org/article/0adb625c4550495bb17bb55f60332f9f
Autor:
Poliana Queiroz-Souza, Adan Galue-Parra, Lienne Silveira Moraes, Caroline Gomes Macedo, Ana Paula Drummond Rodrigues, Victor H. S. Marinho, Fabricio H. Holanda, Irlon M. Ferreira, Edilene Oliveira da Silva
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Leishmaniasis encompasses a cluster of neglected tropical diseases triggered by kinetoplastid phatogens belonging to the genus Leishmania. Current therapeutic approaches are toxic, expensive, and require long-term treatment. Nanoparticles are emergin
Externí odkaz:
https://doaj.org/article/ad08fbad2f184d3183a72c652f8de604
Autor:
Rym Essid, Sarra Kefi, Bilel Damergi, Ghassen Abid, Nadia Fares, Selim Jallouli, Islem Abid, Dina Hussein, Olfa Tabbene, Ferid Limam
Publikováno v:
Molecules, Vol 29, Iss 8, p 1876 (2024)
The present study aimed to evaluate the leishmanicidal potential of the essential oil (EO) of Micromeria (M.) nervosa and to investigate its molecular mechanism of action by qPCR. Furthermore, in silicointeraction study of the major M. nervosa EO com
Externí odkaz:
https://doaj.org/article/7286615813f54774bb58ff0b15226291
Autor:
Alice P. Borges, Malu M. S. Obata, Silvia H. Libardi, Rafael O. Trevisan, Victor M. Deflon, Ulrich Abram, Francis B. Ferreira, Luiz Antônio S. Costa, Antonio O. T. Patrocínio, Marcos V. da Silva, Júlio C. Borges, Pedro I. S. Maia
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 452 (2024)
Leishmaniasis is a group of parasitic diseases with the potential to infect more than 1 billion people; however, its treatment is still old and inadequate. In order to contribute to changing this view, this work consisted of the development of comple
Externí odkaz:
https://doaj.org/article/ea751c10cb2546d0868d017ad900d1b8
Autor:
Virlanna Larissa Santos de Azevedo, Fernanda Costa Rosa, Leo Ruben Lopes Dias, Lucas Abrantes Batista, Mariana Costa Melo, Luis Alfredo Torres Sales, Abia de Jesus Martins Branco, Thalison Rômulo Rocha Araújo, Rita de Cássia Mendonça de Miranda, Amanda Silva dos Santos Aliança
Publikováno v:
Microorganisms, Vol 12, Iss 3, p 476 (2024)
This study aimed to evaluate the antibacterial, leishmanicidal, and cytotoxic potential of metabolites produced by bacteria isolated from rhizosphere soil samples. The bacterium was identified by genome sequencing as Streptomyces kronopolitis. A prel
Externí odkaz:
https://doaj.org/article/2398c6b307614015a8873cbd4ecc3c92
Autor:
Rocío Nieto-Meneses, Rafael Castillo, Alicia Hernández-Campos, Benjamín Nogueda-Torres, Edgar Oliver López-Villegas, Adriana Moreno-Rodríguez, Félix Matadamas-Martínez, Lilián Yépez-Mulia
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 659 (2024)
Chemotherapy currently available for leishmaniasis treatment has many adverse side effects and drug resistance. Therefore, the identification of new targets and the development of new drugs are urgently needed. Previously, we reported the synthesis o
Externí odkaz:
https://doaj.org/article/1c12c711056146e38f7bf99bde04f60a
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Abdur Rauf, Saima Naz, Naveed Muhammad, Abdul Wadood, Adnan Khan, Abdulrahman Alsahammari, Metab Alharbi, Philippe Jeandet
Publikováno v:
Journal of King Saud University: Science, Vol 35, Iss 3, Pp 102572- (2023)
Objective: Medicinal plants are the mainstay of various chemical constituents responsible for curing or mitigating different pathological and non-pathological health issues. In this regard, the current research work was subjected to finding the best
Externí odkaz:
https://doaj.org/article/735262a9b6254b05bdee712e4977da56