Zobrazeno 1 - 10
of 573
pro vyhledávání: '"lectin microarray"'
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 1145-1155 (2024)
Glycosylation, a crucial posttranslational modification, plays a significant role in numerous physiological and pathological processes. Lectin microarrays, which leverage the high specificity of lectins for sugar binding, are ideally suited for profi
Externí odkaz:
https://doaj.org/article/46025a83340f46178ee1e90ae392d155
Autor:
Shen Luo, Baolin Zhang
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Glycosylation plays a crucial role in determining the quality and efficacy of therapeutic antibodies. This necessitates a thorough analysis and monitoring process to ensure consistent product quality during manufacturing. In this study, we introduce
Externí odkaz:
https://doaj.org/article/2fc45c33d15146f88c04bfa0f7ddf063
Autor:
Yuki Yamaguchi, Kentaro Ishii, Sachiko Koizumi, Hiroaki Sakaue, Takahiro Maruno, Mitsuko Fukuhara, Risa Shibuya, Yasuo Tsunaka, Aoba Matsushita, Karin Bandoh, Tetsuo Torisu, Chie Murata-Kishimoto, Azusa Tomioka, Saho Mizukado, Hiroyuki Kaji, Yuji Kashiwakura, Tsukasa Ohmori, Atsushi Kuno, Susumu Uchiyama
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101256- (2024)
Glycosylation of biopharmaceuticals can affect their safety and efficacy. Glycans can occur on recombinant adeno-associated viruses (rAAVs) that are used for gene therapy; however, the types of glycans that attach to rAAVs are controversial. Here, we
Externí odkaz:
https://doaj.org/article/fced777d496a471c898309e23d2e7a7f
Autor:
Hanjie Yu, Mingxiu Li, Jian Shu, Liuyi Dang, Xin Wu, Yuzi Wang, Xuan Wang, Xin Chang, Xiaojuan Bao, Bojing Zhu, Xiameng Ren, Wentian Chen, Yi Li
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-14 (2023)
Abstract Background Osteoarthritis (OA) is the most common form of arthritis, affecting millions of aging people. Investigation of abnormal glycosylation is essential for the understanding of pathological mechanisms of OA. Methods The total protein w
Externí odkaz:
https://doaj.org/article/3bb440ff5bea4cb1948f6cc57407c712
Autor:
Yoko Itakura, Yasuko Hasegawa, Yurika Kikkawa, Yuina Murakami, Kosuke Sugiura, Chiaki Nagai-Okatani, Norihiko Sasaki, Mariko Umemura, Yuji Takahashi, Tohru Kimura, Atsushi Kuno, Toshiyuki Ishiwata, Masashi Toyoda
Publikováno v:
Regenerative Therapy, Vol 22, Iss , Pp 68-78 (2023)
Introduction: Heart failure is caused by various factors, making the underlying pathogenic mechanisms difficult to identify. Since cardiovascular disease tends to worsen over time, early diagnosis is key for treatment. In addition, understanding the
Externí odkaz:
https://doaj.org/article/b2bed5b042084a44a29c66a2c5018059
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-9 (2023)
Abstract Background Takayasu arteritis (TAK) is an autoimmune inflammatory disorder with an undefined etiology. This study aimed to characterize the glycosylation profiles of serum immunoglobulin G (IgG) in patients with TAK. Methods Lectin microarra
Externí odkaz:
https://doaj.org/article/aa4c3b5829c14af7beae9352b69c47a5
Autor:
Yaozheng Xu, Jiawen Huo, Ruili Nie, Lili Ge, Chonghong Xie, Yuan Meng, Jianhua Liu, Lina Wu, Xiaosong Qin
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectivesHashimoto’s thyroiditis (HT) is one of the most common autoimmune disorders; however, its underlying pathological mechanisms remain unclear. Although aberrant glycosylation has been implicated in the N-glycome of immunoglobulin G (IgG), c
Externí odkaz:
https://doaj.org/article/03ad62e8f3bc43168b21ff2290349d85
Autor:
Siting Li, Xiaoli Zeng, Shiyi Tang, Xi Li, Guoyuan Zhang, Mengtao Li, Xiaofeng Zeng, Chaojun Hu
Publikováno v:
PeerJ, Vol 11, p e14853 (2023)
Background Primary Sjögren’s syndrome (PSS) is a systemic autoimmune disease resulting in significant loss of systemic gland secretory function. IgG glycosylation abnormalities had been found to play important roles in autoimmune diseases. Here, w
Externí odkaz:
https://doaj.org/article/8b266fdb5517445c839632d698950909
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Akademický článek
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