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Publikováno v:
Molecules
Molecules, Vol 26, Iss 114, p 114 (2021)
Volume 26
Issue 1
Molecules, Vol 26, Iss 114, p 114 (2021)
Volume 26
Issue 1
Sludge water (SW) arising from the dewatering of anaerobic digested sludge causes high back loads of ammonium, leading to high stress (inhibition of the activity of microorganisms by an oversupply of nitrogen compounds (substrate inhibition)) for was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::705d4e5c1478caec1600d552e9b66325
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 622-629 (2021)
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 622-629 (2021)
Chemical modifications have been extensively used for therapeutic oligonucleotides because they strongly enhance the stability against nucleases, binding affinity to the targets, and efficacy. We previously reported that oligonucleotides modified wit
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 688-704 (2021)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
Pyrrolidones are common heterocyclic fragments in various biologically active compounds. Here, a two-step radical-based approach to γ-lactams bearing three to four stereocenters starting from epoxides, N-allylic silylacetamides and TEMPO is reported
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 749-761 (2021)
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 749-761 (2021)
Two phosphate modifications were introduced into the DNA backbone using the Staudinger reaction between the 3’,5’-dinucleoside β-cyanoethyl phosphite triester formed during DNA synthesis and sulfonyl azides, 4-(azidosulfonyl)-N,N,N-trimethylbuta
Autor:
Vladimir I. Musatov, Maryna O Mazur, Eugene M Zviagin, Oleksii S Zhelavskyi, Elena H. Shvets, Maksim A. Kolosov, Svitlana V. Shishkina, Anna Yu Andryushchenko, Valentyn A. Chebanov
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 678-687 (2021)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
A novel catalyst-free synthetic approach to 1,2,3-triazolobenzodiazepinones has been developed and optimized. The Ugi reaction of 2-azidobenzaldehyde, various amines, isocyanides, and acids followed by microwave-assisted intramolecular azide–alkyne
Autor:
Margus Lopp, Arvi Jõers, Marek Kõllo, Marje Kasari, Tõnis Pehk, Tõnis Kanger, Ivar Järving, Villu Kasari
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 581-588 (2021)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
A method for the synthesis of 9,11-secosteroids starting from the natural corticosteroid cortisol is described. There are two key steps in this approach, combining chemistry and synthetic biology. Stereo- and regioselective hydroxylation at C9 (stero
Autor:
Arif Daştan, Ramazan Koçak
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 719-729 (2021)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
The synthesis of novel polycyclic π-conjugated dihydropyridazines, pyridazines, and pyrroles was studied. Dihydropyridazine dyes were synthesized by inverse electron-demand Diels–Alder cycloaddition reactions between a dibenzosuberenone and tetraz
Autor:
Mari Murakami, Daishi Ishii, Erina Hamada, Tominari Choshi, Nanase Choshi, Yuuto Kihara, Noriyuki Hatae, Takashi Nishiyama, Kimiko Taninaka, Natsumi Nakanishi
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 730-736 (2021)
The first total synthesis of the pyrrolo[2,3-c]quinoline alkaloid trigonoine B (1) was accomplished via a six-step sequence involving the construction of an N-substituted 4-aminopyrrolo[2,3-c]quinoline framework via electrocyclization of 2-(pyrrol-3-
Autor:
Raku Irie, Ryuichi Sakai, Kyosuke Mori, Kei Miyako, Masato Oikawa, Kenji Morokuma, Shuntaro Tsukamoto
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 540-550 (2021)
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 540-550 (2021)
Herein, we report the enantiospecific synthesis of two artificial glutamate analogs designed based on IKM-159, an antagonist selective to the AMPA-type ionotropic glutamate receptor. The synthesis features the chiral resolution of the carboxylic acid
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 511-518 (2021)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
Ligand-targeted microbubbles are focusing interest for molecular imaging and delivery of chemotherapeutics. Novel lipid-peptide conjugates (lipopeptides) that feature alternating serine-glycine (SG) n segments rather than the classical poly(oxyethyle