Zobrazeno 1 - 10
of 184
pro vyhledávání: '"lara testai"'
Autor:
Eugenia Piragine, Martina De Felice, Lorenzo Germelli, Vanessa Brinkmann, Lorenzo Flori, Claudia Martini, Vincenzo Calderone, Natascia Ventura, Eleonora Da Pozzo, Lara Testai
Publikováno v:
Experimental Gerontology, Vol 194, Iss , Pp 112495- (2024)
Aging is one of the main risk factors for neurodegenerative disorders, which represent a global burden on healthcare systems. Therefore, identifying new strategies to slow the progression of brain aging is a compelling challenge. In this article, we
Externí odkaz:
https://doaj.org/article/2aafe5b68c084df8b5bb4c954508caf7
Autor:
Jacopo Spezzini, Valerio Ciccone, Monica Macaluso, Ylenia Pieracci, Guido Flamini, Sandra Donnini, Vincenzo Calderone, Lara Testai, Angela Zinnai
Publikováno v:
Nutrients, Vol 16, Iss 18, p 3172 (2024)
Recently, there has been significant exploration into the utilization of food by-products as natural reservoirs of bioactive substances, particularly in the creation of functional foods naturally enriched with antioxidants. Citrus peels represent a v
Externí odkaz:
https://doaj.org/article/9fd94c57afc64fda8ab416d667401f21
Autor:
Lorenzo Flori, Giulia Lazzarini, Jacopo Spezzini, Andrea Pirone, Vincenzo Calderone, Lara Testai, Vincenzo Miragliotta
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116534- (2024)
The isoproterenol (ISO)-induced myocardial fibrosis is considered a reliable and repeatable experimental model characterized by a relatively low mortality rate. Although is well-known that ISO stimulates the β1 adrenergic receptors at the myocardial
Externí odkaz:
https://doaj.org/article/2526eba311714480b4ce5dfd4c686f8b
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 543 (2024)
Irisin is a myokine secreted under the influence of physical activity and exposure to low temperatures and through different exogenous stimuli by the cleavage of its precursor, fibronectin type III domain-containing protein 5 (FNDC5). It is mainly kn
Externí odkaz:
https://doaj.org/article/5964e6ba918f44a9bb760d544b28f1b2
Autor:
Giada Benedetti, Lorenzo Flori, Jacopo Spezzini, Vincenzo Miragliotta, Giulia Lazzarini, Andrea Pirone, Cosimo Meneguzzo, Luca Tagliavento, Alma Martelli, Michele Antonelli, Davide Donelli, Cecilia Faraloni, Vincenzo Calderone, Francesco Meneguzzo, Lara Testai
Publikováno v:
Nutrients, Vol 16, Iss 4, p 506 (2024)
The healthy properties of pomegranate fruit, a highly consumed food, have been known for a long time. However, the pomegranate supply chain is still rather inefficient, with the non-edible fraction, whose weight is roughly half the total and is endow
Externí odkaz:
https://doaj.org/article/709cbe948d2f494282dfb408f16ac519
Autor:
Lorenzo Flori, Rosangela Montanaro, Eleonora Pagnotta, Luisa Ugolini, Laura Righetti, Alma Martelli, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Vincenzo Brancaleone, Lara Testai, Vincenzo Calderone
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3281 (2023)
Modulation of mitochondrial K channels represents a pharmacological strategy to promote cardioprotective effects. Isothiocyanates emerge as molecules capable of releasing hydrogen sulfide (H2S), an endogenous pleiotropic gasotransmitter responsible f
Externí odkaz:
https://doaj.org/article/8e567d5631784c1c9c6073e4309f3f89
Autor:
Valentina Citi, Elisabetta Barresi, Eugenia Piragine, Jacopo Spezzini, Lara Testai, Federico Da Settimo, Alma Martelli, Sabrina Taliani, Vincenzo Calderone
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16131 (2023)
Metformin (Met) is the first-line therapy in type 2 diabetes mellitus but, in last few years, it has also been evaluated as anti-cancer agent. Several pathways, such as AMPK or PI3K/Akt/mTOR, are likely to be involved in the anti-cancer Met activity.
Externí odkaz:
https://doaj.org/article/f3e934f39bfe4b418e6212127fc5e1ae
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 11886 (2023)
Hydrogen sulfide (H2S), known for many decades exclusively for its toxicity and the smell of rotten eggs, has been re-discovered for its pleiotropic effects at the cardiovascular and non-cardiovascular level. Therefore, great attention is being paid
Externí odkaz:
https://doaj.org/article/d74131d5887b4e8a846f3ff0e21f26f9
Autor:
Giada Benedetti, Federica Zabini, Luca Tagliavento, Francesco Meneguzzo, Vincenzo Calderone, Lara Testai
Publikováno v:
Antioxidants, Vol 12, Iss 7, p 1351 (2023)
Pomegranate (Punica granatum L.) is a polyphenol-rich edible food and medicinal plant of ancient origin, containing flavonols, anthocyanins, and tannins, with ellagitannins as the most abundant polyphenols. In the last decades, its consumption and sc
Externí odkaz:
https://doaj.org/article/f5466cdf84bf47d5be62c977d512c2b9
Autor:
Valentina Citi, Angela Corvino, Ferdinando Fiorino, Francesco Frecentese, Elisa Magli, Elisa Perissutti, Vincenzo Santagada, Simone Brogi, Lorenzo Flori, Era Gorica, Lara Testai, Alma Martelli, Vincenzo Calderone, Giuseppe Caliendo, Beatrice Severino
Publikováno v:
Journal of Advanced Research, Vol 27, Iss , Pp 41-53 (2021)
Introduction: The gasotransmitter hydrogen sulphide (H2S), an endogenous ubiquitous signalling molecule, is known for its beneficial effects on different mammalian systems. H2S exhibits cardioprotective activity against ischemia/reperfusion (I/R) or
Externí odkaz:
https://doaj.org/article/8fc49f98c59742828951e1c1870ef95a