Zobrazeno 1 - 10
of 3 359
pro vyhledávání: '"l-type calcium channel"'
Autor:
Ying Zhang, Hua Chen, Qingmin Ma, Hui Jia, Hongyu Ma, Zishuo Du, Yan Liu, Xiangjian Zhang, Yi Zhang, Yue Guan, Huijie Ma
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 16 (2024)
Background Cardiovascular disease remains one of the leading causes of death globally. Myocardial ischemia and infarction, in particular, frequently cause disturbances in cardiac electrical activity that can trigger ventricular arrhythmias. We aimed
Externí odkaz:
https://doaj.org/article/431e21e28e4249ab87d9477a3742ed6e
Autor:
Taiming Liu, Meijuan Zhang, Shawn Hanson, Rucha Juarez, Sean Wilson, Hobe Schroeder, Qian Li, Lingchao Zhu, Guangyu Zhang, Arlin B. Blood
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract Although the gasotransmitter hydrogen sulfide (H2S) is well known for its vasodilatory effects, H2S also exhibits vasoconstricting properties. Herein, it is demonstrated that administration of H2S as intravenous sodium sulfide (Na2S) increas
Externí odkaz:
https://doaj.org/article/410ed0aeada64958939ca1659544ca8a
Autor:
Varun Kamat, Ian R. Sweet
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionBiphasic insulin secretion is an intrinsic characteristic of the pancreatic islet and has clinical relevance due to the loss of first-phase in patients with Type 2 diabetes. As it has long been shown that first-phase insulin secretion onl
Externí odkaz:
https://doaj.org/article/6fc9e053f75841c9ba246fcaee20d33b
Autor:
Rui YANG, Chang-Li JI, Min ZHANG, Jie ZHANG, Hong-Jie YUAN, Ming-Jiu LUO, Guang-Zhong JIAO, Jing-He TAN
Publikováno v:
The Journal of Reproduction and Development, Vol 69, Iss 4, Pp 185-191 (2023)
The mechanisms underlying postovulatory oocyte aging (POA) remain largely unknown. The expression of the calcium-sensing receptor (CaSR) in mouse oocytes and its role in POA need to be explored. Our objective was to observe CaSR expression and its ro
Externí odkaz:
https://doaj.org/article/5c0f83c100b142778e4ea0a4976467d0
Autor:
Monique Jänsch, Lubomir T. Lubomirov, Maximilian Trum, Tatjana Williams, Joachim Schmitt, Kai Schuh, Fatimunnisa Qadri, Lars S. Maier, Michael Bader, Oliver Ritter
Publikováno v:
FEBS Open Bio, Vol 13, Iss 1, Pp 118-132 (2023)
Recent evidence demonstrated that alterations in the QT interval duration on the ECG are not only determined by mutations in genes for ion channels, but also by modulators of ion channels. Changes in the QT interval duration beyond certain thresholds
Externí odkaz:
https://doaj.org/article/8069512204c84c57aff6a458cf969748
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 11-20 (2023)
Calcium plays a fundamental role in various signaling pathways and cellular processes in the human organism. In the nervous system, voltage-gated calcium channels such as L-type calcium channels (LTCCs) are critical elements in mediating neurotransmi
Externí odkaz:
https://doaj.org/article/5984ac44bc61464398f12a188ea6b136
Akademický článek
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Akademický článek
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Publikováno v:
Physiological Reports, Vol 11, Iss 11, Pp n/a-n/a (2023)
Abstract Ventricular repolarization shows notable sex‐specificity, with female sex being associated with longer QT‐intervals in electrocardiography irrespective of the species studied. From a clinical point of view, women are at a greater risk fo
Externí odkaz:
https://doaj.org/article/dd2c5041ffbc4792a128c46f75d32e9b
Autor:
Yong Qiu, Chiyu Ma, Nan Jiang, Deming Jiang, Zhengyin Yu, Xin Liu, Yuxuan Zhu, Weijie Yu, Fengheng Li, Hao Wan, Ping Wang
Publikováno v:
Biosensors, Vol 14, Iss 1, p 16 (2023)
Calcium ions participate in the regulation of almost all biological functions of the body, especially in cardiac excitation–contraction coupling, acting as vital signaling through ion channels. Various cardiovascular drugs exert their effects via a
Externí odkaz:
https://doaj.org/article/ec48509c2b024a519bc6e68869044561