Antinociceptive activity of Cnicus benedictus L. leaf extract: a mechanistic evaluation

Autor: Davoud Ahmadimoghaddam, Reihaneh Sadeghian, Akram Ranjbar, Zohreh Izadidastenaei, Saeed Mohammadi

Publikováno v: Research in Pharmaceutical Sciences, Vol 15, Iss 5, Pp 463-472 (2020)

Background and purpose: Cnicus benedictus, a medicinal herb, traditionally had been used for the treatment of stomachache pain. In this study, the possible efficacy of Cnicus benedictus leaf methanolic extract (CBHE) and also cnicin, one of its major

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Involvement of L-arginine/NO/cGMP/K(ATP) channel pathway in the peripheral antinociceptive actions of ellagic acid in the rat formalin test.

Autor: Ghorbanzadeh B; Dept. of Pharmacology and Toxicology, School of Pharmacy, Ahvaz Jundishapur Univ. of Med. Sciences (AJUMS), Ahvaz, Iran., Mansouri MT; Dept. of Pharmacology, Physiology and Atherosclerosis Research Centers, School of Medicine, Ahvaz Jundishapur Univ. of Med. Sciences (AJUMS), Ahvaz, Iran. Electronic address: mansouri_smt@yahoo.com., Hemmati AA; Dept. of Pharmacology and Toxicology, School of Pharmacy, Ahvaz Jundishapur Univ. of Med. Sciences (AJUMS), Ahvaz, Iran., Naghizadeh B; Dept. of Pharmacology, Pain and Physiology Research Centers, School of Medicine, Ahvaz Jundishapur Univ. of Med. Sciences (AJUMS), Ahvaz, Iran., Mard SA; Dept. of Physiology, Physiology Research Center, School of Medicine, Ahvaz Jundishapur Univ. of Med. Sciences (AJUMS), Ahvaz, Iran., Rezaie A; Department of Pathobiology, School of Veterinary Medicine, University of Shahid Chamran, Ahvaz, Iran.

Publikováno v: Pharmacology, biochemistry, and behavior [Pharmacol Biochem Behav] 2014 Nov; Vol. 126, pp. 116-21. Date of Electronic Publication: 2014 Sep 30.