Zobrazeno 1 - 10
of 64
pro vyhledávání: '"kuo Ching Sheng"'
Autor:
Ali Zaid, Kothila Tharmarajah, Helen Mostafavi, Joseph R. Freitas, Kuo-Ching Sheng, Suan-Sin Foo, Weiqiang Chen, Jelena Vider, Xiang Liu, Nicholas P. West, Lara J. Herrero, Adam Taylor, Laura K. Mackay, Daniel R. Getts, Nicholas J. C. King, Suresh Mahalingam
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Arthritogenic alphaviruses such as Ross River and Chikungunya viruses cause debilitating muscle and joint pain and pose significant challenges in the light of recent outbreaks. How host immune responses are orchestrated after alphaviral infe
Externí odkaz:
https://doaj.org/article/f8569b9c0cc8402c8c2be12438a0281e
Autor:
Suan-Sin Foo, Weiqiang Chen, Adam Taylor, Kuo-Ching Sheng, Xing Yu, Terk-Shin Teng, Patrick C Reading, Helen Blanchard, Cecilia Garlanda, Alberto Mantovani, Lisa F P Ng, Lara J Herrero, Suresh Mahalingam
Publikováno v:
PLoS Pathogens, Vol 11, Iss 2, p e1004649 (2015)
The rising prevalence of arthritogenic alphavirus infections, including chikungunya virus (CHIKV) and Ross River virus (RRV), and the lack of antiviral treatments highlight the potential threat of a global alphavirus pandemic. The immune responses un
Externí odkaz:
https://doaj.org/article/6838dd42999d48539a22559e59a65ae3
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95208 (2014)
Unraveling the mechanisms of hematopoiesis regulated by multiple cytokines remains a challenge in hematology. IL-3 is an allergic cytokine with the multilineage potential, while CSF-1 is produced in the steady state with restricted lineage coverage.
Externí odkaz:
https://doaj.org/article/c7d6ec5110504ff19db65bb90cd21132
Autor:
Adam Taylor, Kuo-Ching Sheng, Lara J Herrero, Weiqiang Chen, Nestor E Rulli, Suresh Mahalingam
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71146 (2013)
Part of the Togaviridae family, alphaviruses, including chikungunya virus (CHIKV), Sindbis virus (SINV) and Ross River virus (RRV), are able to cause significant inflammatory pathologies ranging from arthritis to encephalitis. Following symptomatic i
Externí odkaz:
https://doaj.org/article/7386531b31a34745a7c5e75c3fb9801b
Autor:
Brett A. Lidbury, Gerald M. McInerney, Andres Merits, Suresh Mahalingam, Liis Karo-Astover, Kuo-Ching Sheng, Julian V. Melton, Bastian Thaa, Michelle Nelson, Lara J. Herrero, Peter W. Gage, Adam Taylor, Gary Ewart
Publikováno v:
Journal of Virology. 90:4150-4159
The alphaviral 6k gene region encodes the two structural proteins 6K protein and, due to a ribosomal frameshift event, the transframe protein (TF). Here, we characterized the role of the 6k proteins in the arthritogenic alphavirus Ross River virus (R
Autor:
Kuo-Ching Sheng1, Pouniotis, Dodie S.1, Wright, Mark D.2, Choon Kit Tang1, Lazoura, Eliada1, Pietersz, Geoffrey A.3, Apostolopoulos, Vasso1 vasso@burnet.edu.au
Publikováno v:
Immunology. Jul2006, Vol. 118 Issue 3, p372-383. 12p. 8 Graphs.
Publikováno v:
Current Medicinal Chemistry. 18:5507-5518
Cancer has long been considered a disease that is associated with immune tolerance. Its connection with inflammation initially appears paradoxical. During the last decade, it has become increasingly clear that immune infiltrates form an integral part
Autor:
Dodie S. Pouniotis, Vasso Apostolopoulos, Geoffrey A. Pietersz, Nicole Brooks, Kuo Ching Sheng
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1798:2286-2295
Cell penetrating peptides (CPP) represent a novel approach to facilitate cytoplasmic delivery of macromolecules. The DNA binding domain of Drosophila Antennapedia contains 60 amino acids and consists of 3 α-helices, with internalizing activity mappe
Publikováno v:
Expert Review of Vaccines. 9:595-600
A successful vaccine for immunotherapy, particularly for solid tumors or viral infections, requires a suitable target antigen and the production of a cytotoxic T-cell response. In addition, CD4 T cells play an important role in cellular immunity. Her
Autor:
Choon Kit Tang, Vasso Apostolopoulos, Kuo-Ching Sheng, Sandra Esparon, Geoffrey A. Pietersz, Owen Proudfoot
Publikováno v:
Biomaterials. 30:1389-1400
Receptor mediated gene delivery is an attractive non-viral method for targeting genetic material to specific cell types. We have previously utilized oxidized (OMPLL) and reduced mannan poly-L-lysine (RMPLL) to target DNA vaccines to antigen presentin