Zobrazeno 1 - 10
of 1 337
pro vyhledávání: '"kun shi"'
Autor:
Qingya Liu, Yun Yang, Meng Pan, Kun Shi, Dong Mo, Yicong Li, Meng Wang, Linfeng Guo, Zhiyong Qian
Publikováno v:
Bioactive Materials, Vol 41, Iss , Pp 413-426 (2024)
Camptothecin (CPT) exhibits potent antitumor activity; however, its clinical application is limited by significant gastrointestinal adverse effects (GAEs). Although the severity of GAEs associated with CPT derivatives has decreased, the incidence rat
Externí odkaz:
https://doaj.org/article/781146cb3c244788a055150516694bb6
Autor:
Dong Liu, Kun Shi, Peng Chen, Nuoxiao Yan, Lishan Ran, Tiit Kutser, Andrew N. Tyler, Evangelos Spyrakos, R. Iestyn Woolway, Yunlin Zhang, Hongtao Duan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Previous studies typically assumed a constant total organic carbon (OC) storage in the lake water column, neglecting its significant variability within a changing world. Based on extensive field data and satellite monitoring techniques, we d
Externí odkaz:
https://doaj.org/article/fabecef17cc24d18a290bf25f1fe82e7
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110751- (2024)
Summary: Acute lung injury (ALI) is a lung disease characterized by an excessive inflammatory response and damage to lung epithelial cells. Atractylodin (ATL) has good anti-inflammatory activity and protects the integrity of the epithelial cell barri
Externí odkaz:
https://doaj.org/article/6a481e128f534b2085c6c684240b12da
Publikováno v:
Advanced Science, Vol 11, Iss 33, Pp n/a-n/a (2024)
Abstract The treatment of colorectal cancer is always a major challenge in the field of cancer research. The number of estimated new cases of colorectal cancer worldwide in 2020 is 1 148 515, and the estimated number of deaths is 576 858, revealing t
Externí odkaz:
https://doaj.org/article/b88f0ebe3d5a4e789a3f2052a872c4f4
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37483- (2024)
Objective: This study aimed to assess the efficacy of a modified exhaust method in pediatric open-heart surgery involving cardiopulmonary bypass. Method: Data from 303 cases conducted at the Department of Cardiac Surgery, Guizhou Hospital, Shanghai C
Externí odkaz:
https://doaj.org/article/1e2a392bed564d14aae8377a80d8b4fa
Autor:
R. Iestyn Woolway, Yan Tong, Lian Feng, Gang Zhao, Dieu Anh Dinh, Haoran Shi, Yunlin Zhang, Kun Shi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Extreme within-lake conditions have the potential to exert detrimental effects on lakes. Here we use satellite observations to investigate how the occurrence of multiple types of extremes, notably algal blooms, lake heatwaves, and low lake l
Externí odkaz:
https://doaj.org/article/3056e0a378454a94bc1e6a81be97b533
Autor:
Lihui Xu, Guiyang Ge, Dongli Li, Jianming Li, Qinglong Gong, Kun Shi, Fei Liu, Naichao Diao, Zhenzhen Cui, Yingyu Liu, Xue Leng, Rui Du
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-12 (2024)
Abstract Background Infectious bovine rhinotracheitis (IBR), caused by Bovine alphaherpesvirus-1 (BoAHV-1), is an acute, highly contagious disease primarily characterized by respiratory tract lesions in infected cattle. Due to its severe pathological
Externí odkaz:
https://doaj.org/article/b003de6bf4ed4fcf9ea5ca3e4ab36052
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Reprogramming of the serine synthesis pathway (SSP) is intricately linked to the progression of epithelial ovarian cancer (EOC). CBR-5884, a selective small-molecule inhibitor targeting phosphoglycerate dehydrogenase (PHGDH), effectively imp
Externí odkaz:
https://doaj.org/article/33bef547af3c44bc9386ae3324793657
Autor:
Hui-Yang Lei, Gui-Lin Pi, Ting He, Rui Xiong, Jing-Ru Lv, Jia-Le Liu, Dong-Qin Wu, Meng-Zhu Li, Kun Shi, Shi-Hong Li, Na-Na Yu, Yang Gao, Hui-Ling Yu, Lin-Yu Wei, Xin Wang, Qiu-Zhi Zhou, Pei-Lin Zou, Jia-Yang Zhou, Ying-Zhou Liu, Nai-Ting Shen, Jie Yang, Dan Ke, Qun Wang, Gong-Ping Liu, Xi-Fei Yang, Jian-Zhi Wang, Ying Yang
Publikováno v:
Military Medical Research, Vol 11, Iss 1, Pp 1-24 (2024)
Abstract Background Episodic memory loss is a prominent clinical manifestation of Alzheimer’s disease (AD), which is closely related to tau pathology and hippocampal impairment. Due to the heterogeneity of brain neurons, the specific roles of diffe
Externí odkaz:
https://doaj.org/article/df673dbc95c04f9d9dc2c62b7ff993ba
Autor:
Jian Liang, Tingting Wang, Qi Wang, Xiaolin Wang, Xinying Fan, Tingting Hu, Xue Leng, Kun Shi, Jianming Li, Qinglong Gong, Rui Du
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Canine distemper (CD) is a virulent disease caused by the canine distemper virus (CDV) in canines and mustelidaes with high mortality. The incidence of CDV is worldwide distribution and it has caused huge economic losses to multiple industries around
Externí odkaz:
https://doaj.org/article/b84ca2d955d14bc296b26438b8f12c51